pilsicainide has been researched along with Tachycardia, Ventricular in 19 studies
pilsicainide: structure given in first source
pilsicainide : A secondary carboxamide resulting from the formal condensation of the amino group of 2,6-dimethylaniline with the carboxy group of (tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetic acid. It is a sodium channel blocker which is used as an antiarrhythmic drug for the management of atrial tachyarrhythmias in Japan.
Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We performed a pilsicainide challenge test in a 38-year-old man who was resuscitated from ventricular fibrillation without apparent baseline electrocardiogram (ECG) abnormality." | 7.73 | Spontaneous polymorphic ventricular tachycardia after administration of pilsicainide in a patient resuscitated from ventricular fibrillation. ( Araki, S; Ogawa, H; Sadanaga, T; Tanaka, Y, 2006) |
| "No evidence of ischemic heart disease was detected." | 5.30 | Class IC antiarrhythmic drugs, flecainide and pilsicainide, produce ST segment elevation simulating inferior myocardial ischemia. ( Ito, H; Nakamura, W; Segawa, K; Tanaka, S; Yoshimoto, N, 1998) |
| "We administered intravenous pilsicainide to 245 consecutive patients with Brugada syndrome (181 patients with spontaneous type 1 ECG, 64 patients with non-type 1 ECG)." | 3.88 | Prognostic Significance of the Sodium Channel Blocker Test in Patients With Brugada Syndrome. ( Ito, H; Kawada, S; Miyamoto, M; Morimoto, Y; Morita, H; Nakagawa, K; Nishii, N; Tachibana, M; Ueoka, A; Watanabe, A, 2018) |
| "We performed a pilsicainide challenge test in a 38-year-old man who was resuscitated from ventricular fibrillation without apparent baseline electrocardiogram (ECG) abnormality." | 3.73 | Spontaneous polymorphic ventricular tachycardia after administration of pilsicainide in a patient resuscitated from ventricular fibrillation. ( Araki, S; Ogawa, H; Sadanaga, T; Tanaka, Y, 2006) |
| "We treated an 88-year-old man with aortic valvular stenosis/insufficiency and paroxysmal atrial fibrillation, who developed ventricular tachycardia due to pilsicainide toxicity." | 3.72 | A case of the toxicity of pilsicainide hydrochloride with comparison of the serial serum pilsicainide levels and electrocardiographic findings. ( Funada, A; Horita, Y; Kaku, B; Kanaya, H; Kitajima, S; Matsumura, M; Satoh, T; Uno, Y; Yamazaki, T, 2004) |
| " During hospitalization, atrial fibrillation developed, and oral pilsicainide was administered." | 3.71 | Class I antiarrhythmic drug and coronary vasospasm-induced T wave alternans and ventricular tachyarrhythmia in a patient with Brugada syndrome and vasospastic angina. ( Aizawa, Y; Chinushi, M; Chinushi, Y; Toida, T, 2002) |
| "As electrocardiography (ECG) revealed ventricular tachycardia (VT), cardioversion was administered but was unsuccessful." | 1.33 | [Case in which magnesium sulfate effectively treated ventricular tachycardia due to overdose of pilsicainide hydrochloride]. ( Mato, T; Moriwaki, R; Nakata, K; Takenouchi, S; Tsutsumi, H; Yamaguchi, A, 2006) |
| "No evidence of ischemic heart disease was detected." | 1.30 | Class IC antiarrhythmic drugs, flecainide and pilsicainide, produce ST segment elevation simulating inferior myocardial ischemia. ( Ito, H; Nakamura, W; Segawa, K; Tanaka, S; Yoshimoto, N, 1998) |
| "Patient 1 had frequent episodes of paroxysmal atrial fibrillation resistant to Class IA drugs." | 1.30 | ST segment elevation in the right precordial leads induced with class IC antiarrhythmic drugs: insight into the mechanism of Brugada syndrome. ( Fujiki, A; Hayashi, H; Inoue, H; Mizumaki, K; Nagasawa, H; Usui, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 13 (68.42) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, CM | 1 |
| Lin, FZ | 1 |
| Chen, YC | 1 |
| Lin, YK | 1 |
| Lu, YY | 1 |
| Wu, CI | 1 |
| Higa, S | 1 |
| Chen, SA | 1 |
| Chen, YJ | 1 |
| Ueoka, A | 1 |
| Morita, H | 1 |
| Watanabe, A | 1 |
| Morimoto, Y | 1 |
| Kawada, S | 1 |
| Tachibana, M | 1 |
| Miyamoto, M | 1 |
| Nakagawa, K | 1 |
| Nishii, N | 1 |
| Ito, H | 2 |
| Dosdall, DJ | 1 |
| Hisada, T | 1 |
| Miyagawa, T | 1 |
| Yakushiji, T | 1 |
| Tsujimoto, T | 1 |
| Sakai, M | 1 |
| Adachi, T | 1 |
| Ikewaki, K | 1 |
| Ogata, K | 1 |
| Ohsuzu, F | 1 |
| Sakurai, Y | 1 |
| Kaneko, Y | 1 |
| Nakajima, T | 1 |
| Kato, T | 1 |
| Kurabayashi, M | 1 |
| Kimura, M | 1 |
| Kobayashi, T | 1 |
| Owada, S | 1 |
| Ashikaga, K | 1 |
| Higuma, T | 1 |
| Sasaki, S | 1 |
| Iwasa, A | 1 |
| Motomura, S | 1 |
| Okumura, K | 1 |
| Takada, Y | 1 |
| Isobe, S | 1 |
| Okada, M | 1 |
| Ando, A | 1 |
| Nonokawa, M | 1 |
| Inden, Y | 1 |
| Tomita, Y | 1 |
| Suzuki, A | 1 |
| Hirai, M | 1 |
| Murohara, T | 1 |
| Kanemoto, M | 1 |
| Shimizu, A | 2 |
| Yamagata, T | 1 |
| Esato, M | 2 |
| Ueyama, T | 2 |
| Yoshiga, Y | 2 |
| Kakugawa, H | 1 |
| Kametani, R | 1 |
| Inoue, N | 1 |
| Sawa, A | 2 |
| Matsuzaki, M | 2 |
| Horita, Y | 1 |
| Kanaya, H | 1 |
| Uno, Y | 1 |
| Yamazaki, T | 1 |
| Kaku, B | 1 |
| Funada, A | 1 |
| Kitajima, S | 1 |
| Matsumura, M | 1 |
| Satoh, T | 1 |
| Nakata, K | 1 |
| Moriwaki, R | 1 |
| Yamaguchi, A | 1 |
| Takenouchi, S | 1 |
| Mato, T | 1 |
| Tsutsumi, H | 1 |
| Nagai, T | 1 |
| Suyama, K | 1 |
| Shimizu, W | 2 |
| Noda, T | 2 |
| Satomi, K | 1 |
| Kurita, T | 1 |
| Aihara, N | 1 |
| Kamakura, S | 1 |
| Aiba, T | 1 |
| Hidaka, I | 1 |
| Uemura, K | 1 |
| Zheng, C | 1 |
| Kamiya, A | 1 |
| Inagaki, M | 1 |
| Sugimachi, M | 1 |
| Sunagawa, K | 1 |
| Sadanaga, T | 1 |
| Araki, S | 1 |
| Tanaka, Y | 1 |
| Ogawa, H | 1 |
| Shinohara, T | 1 |
| Takahashi, N | 1 |
| Saikawa, T | 1 |
| Yoshimatsu, H | 1 |
| Suzuki, S | 1 |
| Sugi, N | 1 |
| Nakamura, W | 1 |
| Segawa, K | 1 |
| Tanaka, S | 1 |
| Yoshimoto, N | 1 |
| Fujiki, A | 1 |
| Usui, M | 1 |
| Nagasawa, H | 1 |
| Mizumaki, K | 1 |
| Hayashi, H | 1 |
| Inoue, H | 1 |
| Chinushi, Y | 1 |
| Chinushi, M | 1 |
| Toida, T | 1 |
| Aizawa, Y | 1 |
| Sahara, M | 1 |
| Sagara, K | 1 |
| Yamashita, T | 1 |
| Abe, T | 1 |
| Kirigaya, H | 1 |
| Nakada, M | 1 |
| Iinuma, H | 1 |
| Fu, LT | 1 |
| Watanabe, H | 1 |
1 trial available for pilsicainide and Tachycardia, Ventricular
| Article | Year |
|---|---|
Effects of antiarrhythmic agents on left ventricular function during exercise in patients with chronic left ventricular dysfunction.
Topics: Aged; Anti-Asthmatic Agents; Chronic Disease; Disopyramide; Exercise; Exercise Test; Female; Heart V | 2004 |
18 other studies available for pilsicainide and Tachycardia, Ventricular
| Article | Year |
|---|---|
Concurrent increases in post-pacing action potential duration and contractility predict occurrence of ventricular arrhythmia.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Heart; Heart Rate; Lidocaine; Male; Myocardial C | 2020 |
Prognostic Significance of the Sodium Channel Blocker Test in Patients With Brugada Syndrome.
Topics: Administration, Intravenous; Adult; Aged; Brugada Syndrome; Death, Sudden, Cardiac; Electrocardiogra | 2018 |
Mapping ventricular fibrillation: a simplified experimental model leads to a complicated result.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Disease Models, Animal; Electrophysiolo | 2009 |
Ventricular fibrillation diagnosed during electrophysiological study for non-sustained tachycardia.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Humans; Japan; Lidocaine; Male | 2010 |
Pilsicainide-induced polymorphic ventricular tachycardia.
Topics: Aged, 80 and over; Anti-Arrhythmia Agents; Electrocardiography; Female; Humans; Lidocaine; Tachycard | 2012 |
Mechanism of ST elevation and ventricular arrhythmias in an experimental Brugada syndrome model.
Topics: Animals; Disease Models, Animal; Dogs; Electrocardiography; Female; In Vitro Techniques; Lidocaine; | 2004 |
Differentiation of the electrophysiological effects on the atrial myocardium between the pure Na channel blocker, pilsicainide, and flecainide.
Topics: Adult; Anti-Arrhythmia Agents; Atrial Flutter; Electrocardiography; Electrophysiologic Techniques, C | 2004 |
A case of the toxicity of pilsicainide hydrochloride with comparison of the serial serum pilsicainide levels and electrocardiographic findings.
Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Creatinine; Drug Overdose; Ele | 2004 |
[Case in which magnesium sulfate effectively treated ventricular tachycardia due to overdose of pilsicainide hydrochloride].
Topics: Adult; Anti-Asthmatic Agents; Drug Overdose; Hemoperfusion; Humans; Infusions, Intravenous; Lidocain | 2006 |
Pilsicainide-induced verapamil sensitive idiopathic left ventricular tachycardia.
Topics: Adult; Anti-Arrhythmia Agents; Drug Combinations; Electrocardiography; Humans; Lidocaine; Male; Tach | 2006 |
Cellular basis for trigger and maintenance of ventricular fibrillation in the Brugada syndrome model: high-resolution optical mapping study.
Topics: Action Potentials; Animals; Cardiovascular Agents; Disease Models, Animal; Dogs; Electrocardiography | 2006 |
Spontaneous polymorphic ventricular tachycardia after administration of pilsicainide in a patient resuscitated from ventricular fibrillation.
Topics: Adult; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Electric Countershock; Humans; Lidocai | 2006 |
Pilsicainide-induced ventricular tachycardia originating from right ventricular outflow tract.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Lidocaine; Middle Aged; Tachycardia, Ve | 2007 |
Pilsicainide-induced Brugada-type ECG and ventricular arrhythmias originating from the left posterior fascicle in a case with Brugada syndrome associated with idiopathic left ventricular tachycardia.
Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Catheter Ablation; Electrocardiography; Electrophysiologic | 2008 |
Class IC antiarrhythmic drugs, flecainide and pilsicainide, produce ST segment elevation simulating inferior myocardial ischemia.
Topics: Anti-Arrhythmia Agents; Diagnosis, Differential; Drug Therapy, Combination; Electrocardiography; Fle | 1998 |
ST segment elevation in the right precordial leads induced with class IC antiarrhythmic drugs: insight into the mechanism of Brugada syndrome.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Flecainide; Follow-Up Studies; Hea | 1999 |
Class I antiarrhythmic drug and coronary vasospasm-induced T wave alternans and ventricular tachyarrhythmia in a patient with Brugada syndrome and vasospastic angina.
Topics: Acetylcholine; Angina Pectoris, Variant; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibril | 2002 |
J wave and ST segment elevation in the inferior leads: a latent type of variant Brugada syndrome?
Topics: Adult; Bundle-Branch Block; Diagnosis, Differential; Electrocardiography; Humans; Lidocaine; Male; S | 2002 |