pilsicainide has been researched along with Long QT Syndrome in 3 studies
pilsicainide: structure given in first source
pilsicainide : A secondary carboxamide resulting from the formal condensation of the amino group of 2,6-dimethylaniline with the carboxy group of (tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetic acid. It is a sodium channel blocker which is used as an antiarrhythmic drug for the management of atrial tachyarrhythmias in Japan.
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The congenital long QT syndrome is an inherited disorder characterized by a delay in cardiac repolarization, leading to lethal cardiac arrhythmias such as torsade de pointes." | 1.31 | Selective block of late currents in the DeltaKPQ Na(+) channel mutant by pilsicainide and lidocaine with distinct mechanisms. ( Arita, M; Kaku, T; Kitabatake, A; Makita, N; Ono, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hasebe, H | 1 |
| Yokoya, T | 1 |
| Murakoshi, N | 1 |
| Kurebayashi, N | 1 |
| Takagi, M | 1 |
| Doi, A | 1 |
| Takeuchi, K | 1 |
| Yoshikawa, J | 1 |
| Ono, K | 1 |
| Kaku, T | 1 |
| Makita, N | 1 |
| Kitabatake, A | 1 |
| Arita, M | 1 |
3 other studies available for pilsicainide and Long QT Syndrome
| Article | Year |
|---|---|
Pilsicainide Administration Unmasks a Phenotype of Brugada Syndrome in a Patient with Overlap Syndrome due to the E1784K SCN5A Mutation.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Humans; Lidocaine; Long QT Syn | 2020 |
Pilsicanide-induced marked T wave alternans and ventricular fibrillation in a patient with Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Humans; Lidocaine; Long QT | 2002 |
Selective block of late currents in the DeltaKPQ Na(+) channel mutant by pilsicainide and lidocaine with distinct mechanisms.
Topics: Animals; Anti-Arrhythmia Agents; Cells, Cultured; Cricetinae; Electrophysiology; Humans; Lidocaine; | 2000 |