pilsicainide has been researched along with Heart Disease, Ischemic in 5 studies
pilsicainide: structure given in first source
pilsicainide : A secondary carboxamide resulting from the formal condensation of the amino group of 2,6-dimethylaniline with the carboxy group of (tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetic acid. It is a sodium channel blocker which is used as an antiarrhythmic drug for the management of atrial tachyarrhythmias in Japan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "No evidence of ischemic heart disease was detected." | 5.30 | Class IC antiarrhythmic drugs, flecainide and pilsicainide, produce ST segment elevation simulating inferior myocardial ischemia. ( Ito, H; Nakamura, W; Segawa, K; Tanaka, S; Yoshimoto, N, 1998) |
| "The aim of this study was to elucidate whether the electrophysiologic properties of pilsicainide, a novel class IC drug with slow kinetic properties, could be altered in the presence of acute myocardial ischemia." | 3.69 | Ischemia enhances use-dependent sodium channel blockade by pilsicainide, a class IC antiarrhythmic agent. ( Ogawa, S; Sadanaga, T, 1994) |
| "No evidence of ischemic heart disease was detected." | 1.30 | Class IC antiarrhythmic drugs, flecainide and pilsicainide, produce ST segment elevation simulating inferior myocardial ischemia. ( Ito, H; Nakamura, W; Segawa, K; Tanaka, S; Yoshimoto, N, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Omichi, C | 1 |
| Fujimoto, N | 1 |
| Kawasaki, A | 1 |
| Kasai, A | 1 |
| Niwano, S | 1 |
| Inuo, K | 1 |
| Morohoshi, Y | 1 |
| Nakayama, S | 1 |
| Yuge, M | 1 |
| Imaki, R | 1 |
| Izumi, T | 1 |
| Sadanaga, T | 1 |
| Ogawa, S | 1 |
| Liu, JX | 1 |
| Tanonaka, K | 1 |
| Ohtsuka, Y | 1 |
| Sakai, Y | 1 |
| Takeo, S | 1 |
| Nakamura, W | 1 |
| Segawa, K | 1 |
| Ito, H | 1 |
| Tanaka, S | 1 |
| Yoshimoto, N | 1 |
5 other studies available for pilsicainide and Heart Disease, Ischemic
| Article | Year |
|---|---|
Ischemia-induced Brugada-type ST-segment alternans and Brugada syndrome.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Brugada Syndrome; Bundle-Branch Block; Coronary Artery | 2010 |
Mexiletine protects myocardium during acute ischemia by opening sarcolemmal K-ATP channel: studies in closed-chest acute ischemia model in rabbits.
Topics: Acute Disease; Animals; Anti-Arrhythmia Agents; ATP-Binding Cassette Transporters; Disease Models, A | 2004 |
Ischemia enhances use-dependent sodium channel blockade by pilsicainide, a class IC antiarrhythmic agent.
Topics: Acute Disease; Aged; Analysis of Variance; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chi-Square | 1994 |
Improvement of ischemia/reperfusion-induced contractile dysfunction of perfused hearts by class Ic antiarrhythmic agents.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Creatine Kinase; Flecainide; Heart; Lidocai | 1993 |
Class IC antiarrhythmic drugs, flecainide and pilsicainide, produce ST segment elevation simulating inferior myocardial ischemia.
Topics: Anti-Arrhythmia Agents; Diagnosis, Differential; Drug Therapy, Combination; Electrocardiography; Fle | 1998 |