pilsicainide has been researched along with Electrocardiogram QT Prolonged in 3 studies
pilsicainide: structure given in first source
pilsicainide : A secondary carboxamide resulting from the formal condensation of the amino group of 2,6-dimethylaniline with the carboxy group of (tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetic acid. It is a sodium channel blocker which is used as an antiarrhythmic drug for the management of atrial tachyarrhythmias in Japan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The congenital long QT syndrome is an inherited disorder characterized by a delay in cardiac repolarization, leading to lethal cardiac arrhythmias such as torsade de pointes." | 1.31 | Selective block of late currents in the DeltaKPQ Na(+) channel mutant by pilsicainide and lidocaine with distinct mechanisms. ( Arita, M; Kaku, T; Kitabatake, A; Makita, N; Ono, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hasebe, H | 1 |
| Yokoya, T | 1 |
| Murakoshi, N | 1 |
| Kurebayashi, N | 1 |
| Takagi, M | 1 |
| Doi, A | 1 |
| Takeuchi, K | 1 |
| Yoshikawa, J | 1 |
| Ono, K | 1 |
| Kaku, T | 1 |
| Makita, N | 1 |
| Kitabatake, A | 1 |
| Arita, M | 1 |
3 other studies available for pilsicainide and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Pilsicainide Administration Unmasks a Phenotype of Brugada Syndrome in a Patient with Overlap Syndrome due to the E1784K SCN5A Mutation.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Humans; Lidocaine; Long QT Syn | 2020 |
Pilsicanide-induced marked T wave alternans and ventricular fibrillation in a patient with Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Humans; Lidocaine; Long QT | 2002 |
Selective block of late currents in the DeltaKPQ Na(+) channel mutant by pilsicainide and lidocaine with distinct mechanisms.
Topics: Animals; Anti-Arrhythmia Agents; Cells, Cultured; Cricetinae; Electrophysiology; Humans; Lidocaine; | 2000 |