pilsicainide has been researched along with Atrioventricular Nodal Re-Entrant Tachycardia in 19 studies
pilsicainide: structure given in first source
pilsicainide : A secondary carboxamide resulting from the formal condensation of the amino group of 2,6-dimethylaniline with the carboxy group of (tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetic acid. It is a sodium channel blocker which is used as an antiarrhythmic drug for the management of atrial tachyarrhythmias in Japan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We performed a pilsicainide challenge test in a 38-year-old man who was resuscitated from ventricular fibrillation without apparent baseline electrocardiogram (ECG) abnormality." | 7.73 | Spontaneous polymorphic ventricular tachycardia after administration of pilsicainide in a patient resuscitated from ventricular fibrillation. ( Araki, S; Ogawa, H; Sadanaga, T; Tanaka, Y, 2006) |
| "No evidence of ischemic heart disease was detected." | 5.30 | Class IC antiarrhythmic drugs, flecainide and pilsicainide, produce ST segment elevation simulating inferior myocardial ischemia. ( Ito, H; Nakamura, W; Segawa, K; Tanaka, S; Yoshimoto, N, 1998) |
| "We administered intravenous pilsicainide to 245 consecutive patients with Brugada syndrome (181 patients with spontaneous type 1 ECG, 64 patients with non-type 1 ECG)." | 3.88 | Prognostic Significance of the Sodium Channel Blocker Test in Patients With Brugada Syndrome. ( Ito, H; Kawada, S; Miyamoto, M; Morimoto, Y; Morita, H; Nakagawa, K; Nishii, N; Tachibana, M; Ueoka, A; Watanabe, A, 2018) |
| "We performed a pilsicainide challenge test in a 38-year-old man who was resuscitated from ventricular fibrillation without apparent baseline electrocardiogram (ECG) abnormality." | 3.73 | Spontaneous polymorphic ventricular tachycardia after administration of pilsicainide in a patient resuscitated from ventricular fibrillation. ( Araki, S; Ogawa, H; Sadanaga, T; Tanaka, Y, 2006) |
| "We treated an 88-year-old man with aortic valvular stenosis/insufficiency and paroxysmal atrial fibrillation, who developed ventricular tachycardia due to pilsicainide toxicity." | 3.72 | A case of the toxicity of pilsicainide hydrochloride with comparison of the serial serum pilsicainide levels and electrocardiographic findings. ( Funada, A; Horita, Y; Kaku, B; Kanaya, H; Kitajima, S; Matsumura, M; Satoh, T; Uno, Y; Yamazaki, T, 2004) |
| " During hospitalization, atrial fibrillation developed, and oral pilsicainide was administered." | 3.71 | Class I antiarrhythmic drug and coronary vasospasm-induced T wave alternans and ventricular tachyarrhythmia in a patient with Brugada syndrome and vasospastic angina. ( Aizawa, Y; Chinushi, M; Chinushi, Y; Toida, T, 2002) |
| "As electrocardiography (ECG) revealed ventricular tachycardia (VT), cardioversion was administered but was unsuccessful." | 1.33 | [Case in which magnesium sulfate effectively treated ventricular tachycardia due to overdose of pilsicainide hydrochloride]. ( Mato, T; Moriwaki, R; Nakata, K; Takenouchi, S; Tsutsumi, H; Yamaguchi, A, 2006) |
| "No evidence of ischemic heart disease was detected." | 1.30 | Class IC antiarrhythmic drugs, flecainide and pilsicainide, produce ST segment elevation simulating inferior myocardial ischemia. ( Ito, H; Nakamura, W; Segawa, K; Tanaka, S; Yoshimoto, N, 1998) |
| "Patient 1 had frequent episodes of paroxysmal atrial fibrillation resistant to Class IA drugs." | 1.30 | ST segment elevation in the right precordial leads induced with class IC antiarrhythmic drugs: insight into the mechanism of Brugada syndrome. ( Fujiki, A; Hayashi, H; Inoue, H; Mizumaki, K; Nagasawa, H; Usui, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 13 (68.42) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, CM | 1 |
| Lin, FZ | 1 |
| Chen, YC | 1 |
| Lin, YK | 1 |
| Lu, YY | 1 |
| Wu, CI | 1 |
| Higa, S | 1 |
| Chen, SA | 1 |
| Chen, YJ | 1 |
| Ueoka, A | 1 |
| Morita, H | 1 |
| Watanabe, A | 1 |
| Morimoto, Y | 1 |
| Kawada, S | 1 |
| Tachibana, M | 1 |
| Miyamoto, M | 1 |
| Nakagawa, K | 1 |
| Nishii, N | 1 |
| Ito, H | 2 |
| Dosdall, DJ | 1 |
| Hisada, T | 1 |
| Miyagawa, T | 1 |
| Yakushiji, T | 1 |
| Tsujimoto, T | 1 |
| Sakai, M | 1 |
| Adachi, T | 1 |
| Ikewaki, K | 1 |
| Ogata, K | 1 |
| Ohsuzu, F | 1 |
| Sakurai, Y | 1 |
| Kaneko, Y | 1 |
| Nakajima, T | 1 |
| Kato, T | 1 |
| Kurabayashi, M | 1 |
| Kimura, M | 1 |
| Kobayashi, T | 1 |
| Owada, S | 1 |
| Ashikaga, K | 1 |
| Higuma, T | 1 |
| Sasaki, S | 1 |
| Iwasa, A | 1 |
| Motomura, S | 1 |
| Okumura, K | 1 |
| Takada, Y | 1 |
| Isobe, S | 1 |
| Okada, M | 1 |
| Ando, A | 1 |
| Nonokawa, M | 1 |
| Inden, Y | 1 |
| Tomita, Y | 1 |
| Suzuki, A | 1 |
| Hirai, M | 1 |
| Murohara, T | 1 |
| Kanemoto, M | 1 |
| Shimizu, A | 2 |
| Yamagata, T | 1 |
| Esato, M | 2 |
| Ueyama, T | 2 |
| Yoshiga, Y | 2 |
| Kakugawa, H | 1 |
| Kametani, R | 1 |
| Inoue, N | 1 |
| Sawa, A | 2 |
| Matsuzaki, M | 2 |
| Horita, Y | 1 |
| Kanaya, H | 1 |
| Uno, Y | 1 |
| Yamazaki, T | 1 |
| Kaku, B | 1 |
| Funada, A | 1 |
| Kitajima, S | 1 |
| Matsumura, M | 1 |
| Satoh, T | 1 |
| Nakata, K | 1 |
| Moriwaki, R | 1 |
| Yamaguchi, A | 1 |
| Takenouchi, S | 1 |
| Mato, T | 1 |
| Tsutsumi, H | 1 |
| Nagai, T | 1 |
| Suyama, K | 1 |
| Shimizu, W | 2 |
| Noda, T | 2 |
| Satomi, K | 1 |
| Kurita, T | 1 |
| Aihara, N | 1 |
| Kamakura, S | 1 |
| Aiba, T | 1 |
| Hidaka, I | 1 |
| Uemura, K | 1 |
| Zheng, C | 1 |
| Kamiya, A | 1 |
| Inagaki, M | 1 |
| Sugimachi, M | 1 |
| Sunagawa, K | 1 |
| Sadanaga, T | 1 |
| Araki, S | 1 |
| Tanaka, Y | 1 |
| Ogawa, H | 1 |
| Shinohara, T | 1 |
| Takahashi, N | 1 |
| Saikawa, T | 1 |
| Yoshimatsu, H | 1 |
| Suzuki, S | 1 |
| Sugi, N | 1 |
| Nakamura, W | 1 |
| Segawa, K | 1 |
| Tanaka, S | 1 |
| Yoshimoto, N | 1 |
| Fujiki, A | 1 |
| Usui, M | 1 |
| Nagasawa, H | 1 |
| Mizumaki, K | 1 |
| Hayashi, H | 1 |
| Inoue, H | 1 |
| Chinushi, Y | 1 |
| Chinushi, M | 1 |
| Toida, T | 1 |
| Aizawa, Y | 1 |
| Sahara, M | 1 |
| Sagara, K | 1 |
| Yamashita, T | 1 |
| Abe, T | 1 |
| Kirigaya, H | 1 |
| Nakada, M | 1 |
| Iinuma, H | 1 |
| Fu, LT | 1 |
| Watanabe, H | 1 |
1 trial available for pilsicainide and Atrioventricular Nodal Re-Entrant Tachycardia
| Article | Year |
|---|---|
Effects of antiarrhythmic agents on left ventricular function during exercise in patients with chronic left ventricular dysfunction.
Topics: Aged; Anti-Asthmatic Agents; Chronic Disease; Disopyramide; Exercise; Exercise Test; Female; Heart V | 2004 |
18 other studies available for pilsicainide and Atrioventricular Nodal Re-Entrant Tachycardia
| Article | Year |
|---|---|
Concurrent increases in post-pacing action potential duration and contractility predict occurrence of ventricular arrhythmia.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Heart; Heart Rate; Lidocaine; Male; Myocardial C | 2020 |
Prognostic Significance of the Sodium Channel Blocker Test in Patients With Brugada Syndrome.
Topics: Administration, Intravenous; Adult; Aged; Brugada Syndrome; Death, Sudden, Cardiac; Electrocardiogra | 2018 |
Mapping ventricular fibrillation: a simplified experimental model leads to a complicated result.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Disease Models, Animal; Electrophysiolo | 2009 |
Ventricular fibrillation diagnosed during electrophysiological study for non-sustained tachycardia.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Humans; Japan; Lidocaine; Male | 2010 |
Pilsicainide-induced polymorphic ventricular tachycardia.
Topics: Aged, 80 and over; Anti-Arrhythmia Agents; Electrocardiography; Female; Humans; Lidocaine; Tachycard | 2012 |
Mechanism of ST elevation and ventricular arrhythmias in an experimental Brugada syndrome model.
Topics: Animals; Disease Models, Animal; Dogs; Electrocardiography; Female; In Vitro Techniques; Lidocaine; | 2004 |
Differentiation of the electrophysiological effects on the atrial myocardium between the pure Na channel blocker, pilsicainide, and flecainide.
Topics: Adult; Anti-Arrhythmia Agents; Atrial Flutter; Electrocardiography; Electrophysiologic Techniques, C | 2004 |
A case of the toxicity of pilsicainide hydrochloride with comparison of the serial serum pilsicainide levels and electrocardiographic findings.
Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Creatinine; Drug Overdose; Ele | 2004 |
[Case in which magnesium sulfate effectively treated ventricular tachycardia due to overdose of pilsicainide hydrochloride].
Topics: Adult; Anti-Asthmatic Agents; Drug Overdose; Hemoperfusion; Humans; Infusions, Intravenous; Lidocain | 2006 |
Pilsicainide-induced verapamil sensitive idiopathic left ventricular tachycardia.
Topics: Adult; Anti-Arrhythmia Agents; Drug Combinations; Electrocardiography; Humans; Lidocaine; Male; Tach | 2006 |
Cellular basis for trigger and maintenance of ventricular fibrillation in the Brugada syndrome model: high-resolution optical mapping study.
Topics: Action Potentials; Animals; Cardiovascular Agents; Disease Models, Animal; Dogs; Electrocardiography | 2006 |
Spontaneous polymorphic ventricular tachycardia after administration of pilsicainide in a patient resuscitated from ventricular fibrillation.
Topics: Adult; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Electric Countershock; Humans; Lidocai | 2006 |
Pilsicainide-induced ventricular tachycardia originating from right ventricular outflow tract.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Lidocaine; Middle Aged; Tachycardia, Ve | 2007 |
Pilsicainide-induced Brugada-type ECG and ventricular arrhythmias originating from the left posterior fascicle in a case with Brugada syndrome associated with idiopathic left ventricular tachycardia.
Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Catheter Ablation; Electrocardiography; Electrophysiologic | 2008 |
Class IC antiarrhythmic drugs, flecainide and pilsicainide, produce ST segment elevation simulating inferior myocardial ischemia.
Topics: Anti-Arrhythmia Agents; Diagnosis, Differential; Drug Therapy, Combination; Electrocardiography; Fle | 1998 |
ST segment elevation in the right precordial leads induced with class IC antiarrhythmic drugs: insight into the mechanism of Brugada syndrome.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Flecainide; Follow-Up Studies; Hea | 1999 |
Class I antiarrhythmic drug and coronary vasospasm-induced T wave alternans and ventricular tachyarrhythmia in a patient with Brugada syndrome and vasospastic angina.
Topics: Acetylcholine; Angina Pectoris, Variant; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibril | 2002 |
J wave and ST segment elevation in the inferior leads: a latent type of variant Brugada syndrome?
Topics: Adult; Bundle-Branch Block; Diagnosis, Differential; Electrocardiography; Humans; Lidocaine; Male; S | 2002 |