pilsicainide has been researched along with Atrial Flutter in 8 studies
pilsicainide: structure given in first source
pilsicainide : A secondary carboxamide resulting from the formal condensation of the amino group of 2,6-dimethylaniline with the carboxy group of (tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetic acid. It is a sodium channel blocker which is used as an antiarrhythmic drug for the management of atrial tachyarrhythmias in Japan.
Atrial Flutter: Rapid, irregular atrial contractions caused by a block of electrical impulse conduction in the right atrium and a reentrant wave front traveling up the inter-atrial septum and down the right atrial free wall or vice versa. Unlike ATRIAL FIBRILLATION which is caused by abnormal impulse generation, typical atrial flutter is caused by abnormal impulse conduction. As in atrial fibrillation, patients with atrial flutter cannot effectively pump blood into the lower chambers of the heart (HEART VENTRICLES).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Administration of pilsicainide, a class IC antiarrhythmic agent, caused Brugada- type ST elevation in a 66-year-old Japanese male who presented with paroxysmal atrial fibrillation (PAF), type I atrial flutter and inducible ventricular fibrillation (VF) during electrophysiological study." | 3.83 | A Novel SCN5A Mutation Associated with Drug Induced Brugada Type ECG. ( Ai, T; Horie, M; Itoh, H; Makiyama, T; Shimizu, A; Turker, I; Ueyama, T; Vatta, M, 2016) |
| "Syncope was abolished after successful radiofrequency catheter ablation of the AFL." | 1.31 | Syncope in patients with atrial flutter during treatment with class Ic antiarrhythmic drugs. ( Azegami, K; Hiejima, K; Hirao, K; Horikawa, T; Kawabata, M; Motokawa, K; Suzuki, F; Suzuki, K, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Turker, I | 1 |
| Makiyama, T | 1 |
| Vatta, M | 1 |
| Itoh, H | 1 |
| Ueyama, T | 2 |
| Shimizu, A | 2 |
| Ai, T | 1 |
| Horie, M | 1 |
| Takami, M | 1 |
| Yoshida, A | 1 |
| Fukuzawa, K | 1 |
| Takei, A | 1 |
| Kanda, G | 1 |
| Takami, K | 1 |
| Kumagai, H | 1 |
| Tanaka, S | 1 |
| Itoh, M | 1 |
| Imamura, K | 1 |
| Fujiwara, R | 1 |
| Suzuki, A | 1 |
| Hirata, K | 1 |
| Kanemoto, M | 1 |
| Yamagata, T | 1 |
| Esato, M | 1 |
| Yoshiga, Y | 1 |
| Kakugawa, H | 1 |
| Kametani, R | 1 |
| Inoue, N | 1 |
| Sawa, A | 1 |
| Matsuzaki, M | 1 |
| Hirao, K | 3 |
| Okishige, K | 1 |
| Yamamoto, N | 1 |
| Otomo, K | 1 |
| Azegami, K | 2 |
| Isobe, M | 2 |
| Chinushi, M | 1 |
| Izumi, D | 1 |
| Furushima, H | 1 |
| Watanabe, H | 1 |
| Aizawa, Y | 1 |
| Kawabata, M | 2 |
| Higuchi, K | 1 |
| Sasaki, T | 1 |
| Furukawa, T | 1 |
| Okada, H | 1 |
| Hachiya, H | 1 |
| Yamashita, T | 1 |
| Oikawa, N | 1 |
| Inoue, H | 1 |
| Murakawa, Y | 1 |
| Nakajima, T | 1 |
| Usui, M | 1 |
| Ajiki, K | 1 |
| Ohkawa, S | 1 |
| Sugimoto, T | 1 |
| Horikawa, T | 1 |
| Suzuki, K | 1 |
| Motokawa, K | 1 |
| Suzuki, F | 1 |
| Hiejima, K | 1 |
8 other studies available for pilsicainide and Atrial Flutter
| Article | Year |
|---|---|
A Novel SCN5A Mutation Associated with Drug Induced Brugada Type ECG.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Base Sequence; Brugada Syndrome; | 2016 |
Rate-dependent and site-specific conduction block at the posterior right atrium and drug effects evaluated using a noncontact mapping system in patients with typical atrial flutter.
Topics: Action Potentials; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Flutter; Cardiac P | 2012 |
Differentiation of the electrophysiological effects on the atrial myocardium between the pure Na channel blocker, pilsicainide, and flecainide.
Topics: Adult; Anti-Arrhythmia Agents; Atrial Flutter; Electrocardiography; Electrophysiologic Techniques, C | 2004 |
Long-term efficacy of hybrid pharmacologic and ablation therapy in patients with pilsicainide-induced atrial flutter.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cardiac Pacing, Artificial; Cathe | 2005 |
Multiple premature beats triggered ventricular arrhythmias during pilsicainide infusion in a patient with inferior ST-segment elevation.
Topics: Adolescent; Anti-Arrhythmia Agents; Atrial Flutter; Electrocardiography; Humans; Infusions, Intraven | 2006 |
Clinical and electrophysiological characteristics of patients having atrial flutter with 1:1 atrioventricular conduction.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Case | 2008 |
Slow abnormal conduction in the low right atrium: its anatomic basis and relevance to atrial reentry.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Flutter; Atrial Function, Right; Dogs; Electric Stimulation; | 1994 |
Syncope in patients with atrial flutter during treatment with class Ic antiarrhythmic drugs.
Topics: Adult; Anti-Arrhythmia Agents; Atrial Flutter; Catheter Ablation; Electrocardiography; Electrophysio | 2001 |