pilsicainide has been researched along with Anterior Fascicular Block in 15 studies
pilsicainide: structure given in first source
pilsicainide : A secondary carboxamide resulting from the formal condensation of the amino group of 2,6-dimethylaniline with the carboxy group of (tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetic acid. It is a sodium channel blocker which is used as an antiarrhythmic drug for the management of atrial tachyarrhythmias in Japan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Population pharmacokinetics (PK) of a sodium channel-blocking antiarrhythmic, pilsicainide, was studied using the nonlinear mixed-effects modeling technique in 91 patients with cardiac arrhythmias (80 suspected Brugada syndrome [BrS] and 11 with atrial fibrillation) who received an intravenous infusion of 10 mg of the drug." | 9.12 | Population pharmacokinetic and pharmacodynamic analysis of a class IC antiarrhythmic, pilsicainide, in patients with cardiac arrhythmias. ( Echizen, H; Kishi, R; Kobayashi, S; Masuhara, K; Matsumoto, N; Mihara, K; Miyake, F; Nakazawa, K; Ogawa, R; Takagi, A; Takahashi, H, 2006) |
| "Population pharmacokinetics (PK) of a sodium channel-blocking antiarrhythmic, pilsicainide, was studied using the nonlinear mixed-effects modeling technique in 91 patients with cardiac arrhythmias (80 suspected Brugada syndrome [BrS] and 11 with atrial fibrillation) who received an intravenous infusion of 10 mg of the drug." | 5.12 | Population pharmacokinetic and pharmacodynamic analysis of a class IC antiarrhythmic, pilsicainide, in patients with cardiac arrhythmias. ( Echizen, H; Kishi, R; Kobayashi, S; Masuhara, K; Matsumoto, N; Mihara, K; Miyake, F; Nakazawa, K; Ogawa, R; Takagi, A; Takahashi, H, 2006) |
| "We administered pilsicainide chloride, a class Ic pure sodium channel blocker, to patients with Brugada syndrome (BS) and evaluated the occurrence of ventricular arrhythmia (VA) and T-wave alternans (TWA)." | 3.72 | Ventricular arrhythmia induced by sodium channel blocker in patients with Brugada syndrome. ( Banba, K; Emori, T; Hina, K; Kita, T; Kusano, KF; Matsubara, H; Morita, H; Morita, ST; Nagase, S; Nakamura, K; Nishii, N; Ohe, T; Tani, Y; Watanabe, A, 2003) |
| " This case report describes a patient in whom a typical Brugada ECG pattern developed during fever and could be reproduced at normal body temperature by administration of pilsicainide." | 3.72 | Brugada-like electrocardiographic pattern unmasked by fever. ( Kanmatsuse, K; Kofune, T; Masaki, R; Okubo, K; Okumura, Y; Oshikawa, N; Ozawa, Y; Saito, S; Sugimura, H; Takagi, Y; Wakita, R; Watanabe, I; Yamada, T, 2004) |
| " During hospitalization, atrial fibrillation developed, and oral pilsicainide was administered." | 3.71 | Class I antiarrhythmic drug and coronary vasospasm-induced T wave alternans and ventricular tachyarrhythmia in a patient with Brugada syndrome and vasospastic angina. ( Aizawa, Y; Chinushi, M; Chinushi, Y; Toida, T, 2002) |
| "Amiodarone (200 mg/day) was administered for 6 months and programmed ventricular stimulation was repeated." | 1.32 | Intravenous administration of class I antiarrhythmic drug induced T wave alternans in an asymptomatic Brugada syndrome patient. ( Kanmatsuse, K; Kasamaki, Y; Kofune, T; Masaki, R; Ohkubo, K; Okumura, Y; Oshikawa, N; Ozawa, Y; Saito, S; Watanabe, I; Yamada, T, 2003) |
| "Ventricular fibrillation was induced with double extrastimuli applied to the right ventricular outflow tract." | 1.31 | [Brugada syndrome occurring in an identical twin: a case report]. ( Fujiki, A; Inoue, H; Mizumaki, K; Nishida, K; Sakabe, M; Sugao, M; Tsuneda, T, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 13 (86.67) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Omichi, C | 1 |
| Fujimoto, N | 1 |
| Kawasaki, A | 1 |
| Kasai, A | 1 |
| Ohkubo, K | 2 |
| Watanabe, I | 3 |
| Okumura, Y | 3 |
| Ashino, S | 1 |
| Kofune, M | 1 |
| Nagashima, K | 1 |
| Nakai, T | 1 |
| Kunimoto, S | 1 |
| Kasamaki, Y | 2 |
| Hirayama, A | 1 |
| Takagi, M | 1 |
| Doi, A | 1 |
| Takeuchi, K | 1 |
| Yoshikawa, J | 1 |
| Sakabe, M | 1 |
| Fujiki, A | 1 |
| Tsuneda, T | 1 |
| Nishida, K | 1 |
| Sugao, M | 1 |
| Mizumaki, K | 1 |
| Inoue, H | 1 |
| Morita, H | 3 |
| Takenaka-Morita, S | 1 |
| Fukushima-Kusano, K | 1 |
| Kobayashi, M | 1 |
| Nagase, S | 3 |
| Kakishita, M | 1 |
| Nakamura, K | 3 |
| Emori, T | 3 |
| Matsubara, H | 3 |
| Ohe, T | 3 |
| Nogami, A | 1 |
| Nakao, M | 1 |
| Kubota, S | 1 |
| Sugiyasu, A | 1 |
| Doi, H | 1 |
| Yokoyama, K | 1 |
| Yumoto, K | 1 |
| Tamaki, T | 1 |
| Kato, K | 1 |
| Hosokawa, N | 1 |
| Sagai, H | 1 |
| Nakamura, H | 1 |
| Nitta, J | 1 |
| Yamauchi, Y | 1 |
| Aonuma, K | 1 |
| Yamada, T | 2 |
| Masaki, R | 2 |
| Kofune, T | 2 |
| Oshikawa, N | 2 |
| Saito, S | 2 |
| Ozawa, Y | 2 |
| Kanmatsuse, K | 2 |
| Furuhashi, M | 1 |
| Uno, K | 1 |
| Satoh, S | 1 |
| Hoshikawa, K | 1 |
| Sakai, E | 1 |
| Tsuchihashi, K | 1 |
| Shimamoto, K | 1 |
| Morita, ST | 1 |
| Banba, K | 1 |
| Nishii, N | 1 |
| Tani, Y | 1 |
| Watanabe, A | 1 |
| Kusano, KF | 2 |
| Hina, K | 1 |
| Kita, T | 1 |
| Wakita, R | 1 |
| Takagi, Y | 1 |
| Okubo, K | 1 |
| Sugimura, H | 1 |
| Ogawa, R | 1 |
| Kishi, R | 1 |
| Mihara, K | 1 |
| Takahashi, H | 1 |
| Takagi, A | 1 |
| Matsumoto, N | 1 |
| Masuhara, K | 1 |
| Nakazawa, K | 1 |
| Miyake, F | 1 |
| Kobayashi, S | 1 |
| Echizen, H | 1 |
| Takenaka, S | 1 |
| Hisamatsu, K | 1 |
| Shimizu, W | 1 |
| Aiba, T | 1 |
| Kurita, T | 1 |
| Kamakura, S | 1 |
| Chinushi, Y | 1 |
| Chinushi, M | 1 |
| Toida, T | 1 |
| Aizawa, Y | 1 |
| Sahara, M | 1 |
| Sagara, K | 1 |
| Yamashita, T | 1 |
| Abe, T | 1 |
| Kirigaya, H | 1 |
| Nakada, M | 1 |
| Iinuma, H | 1 |
| Fu, LT | 1 |
| Watanabe, H | 1 |
1 trial available for pilsicainide and Anterior Fascicular Block
| Article | Year |
|---|---|
Population pharmacokinetic and pharmacodynamic analysis of a class IC antiarrhythmic, pilsicainide, in patients with cardiac arrhythmias.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Bundle-Branch Block; | 2006 |
14 other studies available for pilsicainide and Anterior Fascicular Block
| Article | Year |
|---|---|
Ischemia-induced Brugada-type ST-segment alternans and Brugada syndrome.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Brugada Syndrome; Bundle-Branch Block; Coronary Artery | 2010 |
A new criteria differentiating type 2 and 3 Brugada patterns from ordinary incomplete right bundle branch block.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Bundle-Branch Block; Diagnosis, Differential; Elect | 2011 |
Pilsicanide-induced marked T wave alternans and ventricular fibrillation in a patient with Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Humans; Lidocaine; Long QT | 2002 |
[Brugada syndrome occurring in an identical twin: a case report].
Topics: Anti-Arrhythmia Agents; Bundle-Branch Block; Diseases in Twins; Electrocardiography; Humans; Lidocai | 2002 |
Risk stratification for asymptomatic patients with Brugada syndrome.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Bundle-Branch Block; Cardiac Pacing, Artificial; Electrocardiog | 2003 |
Enhancement of J-ST-segment elevation by the glucose and insulin test in Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Glucose; Heart Arrest; Huma | 2003 |
Intravenous administration of class I antiarrhythmic drug induced T wave alternans in an asymptomatic Brugada syndrome patient.
Topics: Amiodarone; Anti-Arrhythmia Agents; Bundle-Branch Block; Cardiac Pacing, Artificial; Electrocardiogr | 2003 |
Right bundle branch block and coved-type ST-segment elevation mimicked by acute cholecystitis.
Topics: Aged; Bundle-Branch Block; Cholecystitis, Acute; Diagnosis, Differential; Electrocardiography; Femal | 2003 |
Ventricular arrhythmia induced by sodium channel blocker in patients with Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bundle-Branch Block; Electrocardiography; Femal | 2003 |
Brugada-like electrocardiographic pattern unmasked by fever.
Topics: Adult; Body Temperature; Bundle-Branch Block; Electrocardiography; Fever; Humans; Lidocaine; Male; S | 2004 |
Relatively benign clinical course in asymptomatic patients with brugada-type electrocardiogram without family history of sudden death.
Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Death, Sudden, Cardiac; Electrocardiography; Ele | 2001 |
Paradoxic abbreviation of repolarization in epicardium of the right ventricular outflow tract during augmentation of Brugada-type ST segment elevation.
Topics: Anti-Arrhythmia Agents; Bundle-Branch Block; Cardiotonic Agents; Electrocardiography; Heart Ventricl | 2001 |
Class I antiarrhythmic drug and coronary vasospasm-induced T wave alternans and ventricular tachyarrhythmia in a patient with Brugada syndrome and vasospastic angina.
Topics: Acetylcholine; Angina Pectoris, Variant; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibril | 2002 |
J wave and ST segment elevation in the inferior leads: a latent type of variant Brugada syndrome?
Topics: Adult; Bundle-Branch Block; Diagnosis, Differential; Electrocardiography; Humans; Lidocaine; Male; S | 2002 |