pilocarpine has been researched along with Weight Gain in 9 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Weight Gain: Increase in BODY WEIGHT over existing weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We investigated the effects of ketogenic diets (KDs) containing coconut oil, triheptanoin, or soybean oil on pilocarpine-induced status epilepticus (SE) in rats." | 7.81 | Effects of ketogenic diets on the occurrence of pilocarpine-induced status epilepticus of rats. ( Barros, EM; Bueno, NB; Cabral-Junior, CR; da Rocha Ataide, T; Domingos, BR; Ferreira, RC; Galvão, JA; Gama, IR; Melo, IT; Oliveira, SL; Pereira, WS; Trindade-Filho, EM, 2015) |
| "Seizures were induced in female Wistar albino rats at either 35 or 55 days of age with a single systemic injection of lithium (3 mEq/kg) and pilocarpine (30 mg/kg); the rats were then treated with the atypical neuroleptic acepromazine (25 mg/kg)." | 7.73 | Extreme obesity in female rats following prepuberal induction of lithium-pilocarpine seizures and a single injection of acepromazine. ( Persinger, MA; St-Pierre, LS, 2005) |
| " To determine if mTOR activation is necessary for abnormal granule cell development, transgenic mice that harbored fluorescently-labeled adult-born granule cells were treated with rapamycin following pilocarpine-induced status epilepticus." | 3.83 | Impact of rapamycin on status epilepticus induced hippocampal pathology and weight gain. ( Danzer, SC; Garcia-Cairasco, N; Hester, MS; Hosford, BE; LaSarge, CL; Liska, JP; Rolle, IJ; Santos, VR; Singh, SP, 2016) |
| " We investigated the effects of ketogenic diets (KDs) containing coconut oil, triheptanoin, or soybean oil on pilocarpine-induced status epilepticus (SE) in rats." | 3.81 | Effects of ketogenic diets on the occurrence of pilocarpine-induced status epilepticus of rats. ( Barros, EM; Bueno, NB; Cabral-Junior, CR; da Rocha Ataide, T; Domingos, BR; Ferreira, RC; Galvão, JA; Gama, IR; Melo, IT; Oliveira, SL; Pereira, WS; Trindade-Filho, EM, 2015) |
| "Extreme obesity slowly develops in female rats over the months following seizures induced by a single systemic injection of lithium and pilocarpine if the resulting limbic seizures are treated with the atypical neuroleptic acepromazine (but not with ketamine)." | 3.75 | Insidious weight gain in prepubertal seized rats treated with an atypical neuroleptic: the role of food consumption, fluid consumption, and spontaneous ambulatory activity. ( Bubenik, GA; Parker, GH; Persinger, MA; St-Pierre, LS, 2009) |
| "Seizures were induced in female Wistar albino rats at either 35 or 55 days of age with a single systemic injection of lithium (3 mEq/kg) and pilocarpine (30 mg/kg); the rats were then treated with the atypical neuroleptic acepromazine (25 mg/kg)." | 3.73 | Extreme obesity in female rats following prepuberal induction of lithium-pilocarpine seizures and a single injection of acepromazine. ( Persinger, MA; St-Pierre, LS, 2005) |
| "We investigated the influence of the streptozocin (STZ)-diabetic state on the dose-response curves for salivary flow and protein content in saliva stimulated by pilocarpine and noradrenaline in mice." | 1.29 | The streptozocin-diabetic state depresses saliva secretion stimulated by pilocarpine and noradrenaline in mice. ( Chen, FJ; Kimura, I; Kimura, M; Miyamoto, H, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gama, IR | 1 |
| Trindade-Filho, EM | 1 |
| Oliveira, SL | 1 |
| Bueno, NB | 1 |
| Melo, IT | 1 |
| Cabral-Junior, CR | 1 |
| Barros, EM | 1 |
| Galvão, JA | 1 |
| Pereira, WS | 1 |
| Ferreira, RC | 1 |
| Domingos, BR | 1 |
| da Rocha Ataide, T | 1 |
| Pessoa, D | 1 |
| Cruz, R | 1 |
| Machado, B | 1 |
| Tenorio, B | 1 |
| Nogueira, R | 1 |
| Hester, MS | 1 |
| Hosford, BE | 1 |
| Santos, VR | 1 |
| Singh, SP | 1 |
| Rolle, IJ | 1 |
| LaSarge, CL | 1 |
| Liska, JP | 1 |
| Garcia-Cairasco, N | 1 |
| Danzer, SC | 1 |
| St-Pierre, LS | 2 |
| Bubenik, GA | 1 |
| Parker, GH | 1 |
| Persinger, MA | 3 |
| Sung, JM | 1 |
| Kuo, SC | 1 |
| Guo, HR | 1 |
| Chuang, SF | 1 |
| Lee, SY | 1 |
| Huang, JJ | 1 |
| Kimura, I | 1 |
| Miyamoto, H | 1 |
| Chen, FJ | 1 |
| Kimura, M | 1 |
| Jedrzejko, C | 1 |
| Peters, JP | 1 |
| Hibbard, B | 1 |
| Shen, RY | 1 |
| Chester, ST | 1 |
| Kroger, AM | 1 |
1 trial available for pilocarpine and Weight Gain
| Article | Year |
|---|---|
Decreased salivary flow rate as a dipsogenic factor in hemodialysis patients: evidence from an observational study and a pilocarpine clinical trial.
Topics: Body Weight; Cross-Over Studies; Humans; Kinetics; Muscarinic Agonists; Pilocarpine; Pilot Projects; | 2005 |
8 other studies available for pilocarpine and Weight Gain
| Article | Year |
|---|---|
Effects of ketogenic diets on the occurrence of pilocarpine-induced status epilepticus of rats.
Topics: Animals; Coconut Oil; Convulsants; Diet, Ketogenic; Dietary Fats; Energy Intake; Male; Neuroprotecti | 2015 |
Analysis of electrocorticographic patterns in rats fed standard or hyperlipidic diets in a normal state or during status epilepticus.
Topics: Algorithms; Alpha Rhythm; Animals; Beta Rhythm; Brain Waves; Computational Biology; Cortical Excitab | 2016 |
Impact of rapamycin on status epilepticus induced hippocampal pathology and weight gain.
Topics: Animals; Carrier Proteins; Cation Transport Proteins; Cell Movement; Disease Models, Animal; Gene Ex | 2016 |
Insidious weight gain in prepubertal seized rats treated with an atypical neuroleptic: the role of food consumption, fluid consumption, and spontaneous ambulatory activity.
Topics: Acepromazine; Analysis of Variance; Animals; Antipsychotic Agents; Body Weight; Disease Models, Anim | 2009 |
Extreme obesity in female rats following prepuberal induction of lithium-pilocarpine seizures and a single injection of acepromazine.
Topics: Acepromazine; Animals; Body Weight; Chlorpromazine; Convulsants; Dopamine Antagonists; Female; Lithi | 2005 |
The streptozocin-diabetic state depresses saliva secretion stimulated by pilocarpine and noradrenaline in mice.
Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred | 1996 |
Weight gain in post-seized rats is facilitated by adding aspirin, glucose, or glucose-taurine-acetaminophen to food mush.
Topics: Acepromazine; Acetaminophen; Animals; Aspirin; Glucose; Hypothalamic Area, Lateral; Injections, Subc | 2001 |
Pilocarpine and digestive efficiency in beef cattle fed a high-concentrate diet.
Topics: Administration, Oral; Animal Feed; Animals; Cattle; Digestion; Dose-Response Relationship, Drug; Eat | 1991 |