pilocarpine has been researched along with Sialorrhea in 7 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Sialorrhea: Increased salivary flow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate and compare the efficacy of pilocarpine and artificial saliva as symptomatic treatments for xerostomia and xerophthalmia in patients with SS." | 9.27 | Pilocarpine and artificial saliva for the treatment of xerostomia and xerophthalmia in Sjögren syndrome: a double-blind randomized controlled trial. ( Cifuentes, M; Del Barrio-Díaz, P; Vera-Kellet, C, 2018) |
| "To investigate and compare the efficacy of pilocarpine and artificial saliva as symptomatic treatments for xerostomia and xerophthalmia in patients with SS." | 5.27 | Pilocarpine and artificial saliva for the treatment of xerostomia and xerophthalmia in Sjögren syndrome: a double-blind randomized controlled trial. ( Cifuentes, M; Del Barrio-Díaz, P; Vera-Kellet, C, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cifuentes, M | 1 |
| Del Barrio-Díaz, P | 1 |
| Vera-Kellet, C | 1 |
| YOSHIMURA, H | 1 |
| INOUE, T | 1 |
| IMAI, Y | 1 |
| YOSHIMURA, F | 1 |
| YAMAWAKI, T | 1 |
| JUNQUEIRA, LC | 1 |
| TOLEDO, AM | 1 |
| SAAD, A | 1 |
| EMMELIN, N | 1 |
| SCHNEYER, LH | 1 |
| SCHNEYER, CA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Oral Pilocarpine in the Treatment of the Dry Eye of Patients With Sjogrens Syndrome[NCT04470479] | Phase 3 | 32 participants (Actual) | Interventional | 2005-03-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pilocarpine and Sialorrhea
| Article | Year |
|---|---|
SECRETORY NERVES OF THE SALIVARY GLANDS.
Topics: Acetylcholine; Carbachol; Cats; Electric Stimulation; Guanethidine; Parasympathetic Nervous System; | 1964 |
1 trial available for pilocarpine and Sialorrhea
| Article | Year |
|---|---|
Pilocarpine and artificial saliva for the treatment of xerostomia and xerophthalmia in Sjögren syndrome: a double-blind randomized controlled trial.
Topics: Administration, Oral; Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Muscarini | 2018 |
5 other studies available for pilocarpine and Sialorrhea
| Article | Year |
|---|---|
Drug-induced sialorrhoea and excessive saliva accumulation.
Topics: Antipsychotic Agents; Benzodiazepines; Cholinesterase Inhibitors; Clozapine; Deglutition Disorders; | 2009 |
Studies on mechanism of salivary secretion.
Topics: Amylases; Bicarbonates; Electrophysiological Phenomena; Electrophysiology; Humans; Parotid Gland; Pi | 1962 |
THE MODE OF ACTION OF RESERPINE ON THE SALIVARY SECRETION OF THE SUBMAXILLARY GLAND IN DOG.
Topics: Carotid Arteries; Dogs; Injections; Injections, Intravenous; Pilocarpine; Research; Reserpine; Saliv | 1963 |
STUDIES ON THE PHYSIOLOGY OF RAT AND MOUSE SUBMAXILLARY GLANDS. I. AMYLASE AND PROTEASE ACTIVITIES IN SERUM, SUBMAXILLARY GLAND, AND SUBMAXILLARY SALIVA OF RAT AND MOUSE.
Topics: Amylases; Animals; Blood; Carbachol; Epinephrine; Histocytochemistry; Kidney; Mice; Parasympathomime | 1964 |
ELECTROLYTE SECRETION BY RAT SALIVARY GLANDS IN VIVO AND IN VITRO.
Topics: Electrolytes; In Vitro Techniques; Inulin; Oxygen; Pancreas; Parotid Gland; Pharmacology; Pilocarpin | 1964 |