pilocarpine has been researched along with Schizophrenia in 2 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Behaviors of calcium/calmodulin-dependent protein kinase II alpha (α-CaMKII) heterozygous knock-out (KO) mice, which are a representative bipolar disorder/schizophrenia model displaying iDG, and pilocarpine-treated mice, which are a representative epilepsy model, were tested followed by quantitative polymerase chain reaction (qPCR)/immunohistochemistry for mRNA/protein expression associated with an iDG phenotype." | 3.79 | The immature dentate gyrus represents a shared phenotype of mouse models of epilepsy and psychiatric disease. ( Chen, Q; Gross, AK; Hagihara, H; Heusner, CL; Kobayashi, K; Kogan, JH; Matsumoto, M; Miyakawa, T; Miyake, S; Shin, R; Tajinda, K; Tamura, K; Walton, NM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L | 1 |
| Xu, J | 1 |
| Zhu, L | 1 |
| Xu, P | 1 |
| Chang, L | 1 |
| Han, Y | 1 |
| Wu, Q | 1 |
| Shin, R | 1 |
| Kobayashi, K | 1 |
| Hagihara, H | 1 |
| Kogan, JH | 1 |
| Miyake, S | 1 |
| Tajinda, K | 1 |
| Walton, NM | 1 |
| Gross, AK | 1 |
| Heusner, CL | 1 |
| Chen, Q | 1 |
| Tamura, K | 1 |
| Miyakawa, T | 1 |
| Matsumoto, M | 1 |
2 other studies available for pilocarpine and Schizophrenia
| Article | Year |
|---|---|
Disrupted in Schizophrenia 1 Reverse Ectopic Migration of Neural Precursors in Mouse Hilus After Pilocarpine-Induced Status Epilepticus.
Topics: Animals; Mice; Neurogenesis; Pilocarpine; Schizophrenia; Seizures; Status Epilepticus | 2023 |
The immature dentate gyrus represents a shared phenotype of mouse models of epilepsy and psychiatric disease.
Topics: Animals; Behavioral Symptoms; Biomarkers; Bipolar Disorder; Calbindin 2; Dentate Gyrus; Disease Mode | 2013 |