pilocarpine has been researched along with Recrudescence in 45 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, the PPARγ agonist rosiglitazone inhibited increases in BDNF and TrkB after status epilepticus (SE), and also prevented hippocampal neuronal loss." | 7.79 | The PPARγ agonist rosiglitazone prevents neuronal loss and attenuates development of spontaneous recurrent seizures through BDNF/TrkB signaling following pilocarpine-induced status epilepticus. ( GuiLian, Z; HaiQin, W; Hong, S; HuQing, W; Li, Y; Ning, B; Ru, Z; ShuQin, Z; Xin, Y; YongNan, L, 2013) |
| "The effects of repetitive pilocarpine-induced status epilepticus (SE) in the hippocampal Na(+)/K(+)ATPase activity were studied in developing rat." | 7.74 | The Na+/K+ATPase activity is increased in the hippocampus after multiple status epilepticus induced by pilocarpine in developing rats. ( Arida, RM; da Silva Fernandes, MJ; Mara de Oliveira, D; Reime Kinjo, E, 2007) |
| "Pilocarpine administration to rats results in status epilepticus (SE) and after a latency period to the occurrence of spontaneous seizures." | 7.74 | Cyclicity of spontaneous recurrent seizures in pilocarpine model of temporal lobe epilepsy in rat. ( Goffin, K; Nissinen, J; Pitkänen, A; Van Laere, K, 2007) |
| "Pilocarpine-induced seizures are mediated by the M(1) subtype of muscarinic acetylcholine receptor (mAChR), but little is known about the signaling mechanisms linking the receptor to seizures." | 7.71 | The role of muscarinic acetylcholine receptor-mediated activation of extracellular signal-regulated kinase 1/2 in pilocarpine-induced seizures. ( Berkeley, JL; Decker, MJ; Levey, AI, 2002) |
| " To address this issue further, we asked whether the new hilar granule cells were active during spontaneous limbic seizures that follow status epilepticus induced by pilocarpine injection." | 7.71 | Spontaneous recurrent seizures after pilocarpine-induced status epilepticus activate calbindin-immunoreactive hilar cells of the rat dentate gyrus. ( Goodman, JH; Scharfman, HE; Sollas, AL, 2002) |
| "Structural brain damage promoted by pilocarpine-induced status epilepticus may underlie or be associated with recurrent spontaneous seizures in mice." | 7.69 | The pilocarpine model of epilepsy in mice. ( Cavalheiro, EA; Priel, MR; Santos, NF, 1996) |
| "Pilocarpine (PILO) administered to rats acutely induces status epilepticus (acute period), which is followed by a transient seizure-free period (silent period), and finally by a chronic phase of spontaneous recurrent seizures (chronic period, SRS) that lasts for the rest of animal's life." | 7.69 | Profile of prostaglandin levels in the rat hippocampus in pilocarpine model of epilepsy. ( Bellíssimo, MI; Cavalheiro, EA; Naffah-Mazzacoratti, MG, 1995) |
| "Bromodeoxyuridine (BrdU) was intraperitoneally administered 36h before the rats were sacrificed." | 5.34 | Consequences of pilocarpine-induced recurrent seizures in neonatal rats. ( Ji-Wen, W; Ruo-Peng, S; Xiu-Yu, S, 2007) |
| " Among post-status epilepticus models, induction of systemic kainic acid or pilocarpine-induced epilepsy is less labor-intensive than electrical-stimulation models and these models mirror the clinicopathologic features of MTLE more closely than do kindling, tetanus toxin, hyperthermia, post-traumatic, and perinatal hypoxia/ischemia models." | 4.84 | Mesial temporal lobe epilepsy: pathogenesis, induced rodent models and lesions. ( Jordan, WH; Miller, MA; Reams, RY; Sharma, AK; Snyder, PW; Thacker, HL, 2007) |
| " In this study, we ablated the hippocampal neurogenesis by methylazoxymethanol acetate (MAM) treatment both before and after pilocarpine induced status epilepticus (SE)." | 3.85 | Reduced abnormal integration of adult-generated granule cells does not attenuate spontaneous recurrent seizures in mice. ( Feng, GF; Hu, M; Liu, JX; Liu, Y; Yuan, B; Zhu, K, 2017) |
| " In the present study, the PPARγ agonist rosiglitazone inhibited increases in BDNF and TrkB after status epilepticus (SE), and also prevented hippocampal neuronal loss." | 3.79 | The PPARγ agonist rosiglitazone prevents neuronal loss and attenuates development of spontaneous recurrent seizures through BDNF/TrkB signaling following pilocarpine-induced status epilepticus. ( GuiLian, Z; HaiQin, W; Hong, S; HuQing, W; Li, Y; Ning, B; Ru, Z; ShuQin, Z; Xin, Y; YongNan, L, 2013) |
| " Using pimonidazole, which probes hypoxic insults, we found that by increasing the duration of pilocarpine-induced status epilepticus (SE) from 30 to 120 min, counts of pimonidazole-immunoreactive neurons also increased (P < 0." | 3.79 | Hypoxia markers are expressed in interneurons exposed to recurrent seizures. ( Biagini, G; Gualtieri, F; Longo, D; Marinelli, C; Meletti, S; Nichelli, PF; Pugnaghi, M, 2013) |
| "Both proconvulsive and anticonvulsive roles of leptin have been reported, suggesting cell-specific actions of leptin in different models of seizure and epilepsy." | 3.79 | Protective role of astrocytic leptin signaling against excitotoxicity. ( Hsuchou, H; Jayaram, B; Kastin, AJ; Khan, RS; Pan, W; Wu, X, 2013) |
| " We sought to determine which cells express P450cc and whether neurosteroids play a role in the regulation of epileptogenesis following pilocarpine-induced status epilepticus (SE)." | 3.75 | Neurosteroids and epileptogenesis in the pilocarpine model: evidence for a relationship between P450scc induction and length of the latent period. ( Avoli, M; Baldelli, E; Bertazzoni, G; Biagini, G; Longo, D; Rogawski, MA; Zoli, M, 2009) |
| "The effects of repetitive pilocarpine-induced status epilepticus (SE) in the hippocampal Na(+)/K(+)ATPase activity were studied in developing rat." | 3.74 | The Na+/K+ATPase activity is increased in the hippocampus after multiple status epilepticus induced by pilocarpine in developing rats. ( Arida, RM; da Silva Fernandes, MJ; Mara de Oliveira, D; Reime Kinjo, E, 2007) |
| "Pilocarpine administration to rats results in status epilepticus (SE) and after a latency period to the occurrence of spontaneous seizures." | 3.74 | Cyclicity of spontaneous recurrent seizures in pilocarpine model of temporal lobe epilepsy in rat. ( Goffin, K; Nissinen, J; Pitkänen, A; Van Laere, K, 2007) |
| " In this study, immature rats were exposed to status epilepticus (SE) followed by a series of 25 flurothyl-induced seizures, SE alone, 25 flurothyl-induced seizures alone, or no seizures." | 3.72 | Cognitive impairment following status epilepticus and recurrent seizures during early development: support for the "two-hit hypothesis". ( Hoffmann, AF; Holmes, GL; Zhao, Q, 2004) |
| "A pilocarpine-induced SRS model of epilepsy affords a reliable model of epileptogenesis suitable for evaluating new chemical entities as putative antiepileptogenics." | 3.72 | Implementing a bioassay to screen molecules for antiepileptogenic activity: chronic pilocarpine versus subdudral haematoma models. ( Lyon, A; Marone, S; Wainman, D; Weaver, DF, 2004) |
| " To address this issue further, we asked whether the new hilar granule cells were active during spontaneous limbic seizures that follow status epilepticus induced by pilocarpine injection." | 3.71 | Spontaneous recurrent seizures after pilocarpine-induced status epilepticus activate calbindin-immunoreactive hilar cells of the rat dentate gyrus. ( Goodman, JH; Scharfman, HE; Sollas, AL, 2002) |
| "Pilocarpine-induced seizures are mediated by the M(1) subtype of muscarinic acetylcholine receptor (mAChR), but little is known about the signaling mechanisms linking the receptor to seizures." | 3.71 | The role of muscarinic acetylcholine receptor-mediated activation of extracellular signal-regulated kinase 1/2 in pilocarpine-induced seizures. ( Berkeley, JL; Decker, MJ; Levey, AI, 2002) |
| " The pilocarpine model of limbic epilepsy involves inducing status epilepticus (SE) with the subsequent development of spontaneous recurrent seizures (SRSs) and is widely accepted as a model of limbic epilepsy in humans." | 3.70 | NMDA receptor activation during status epilepticus is required for the development of epilepsy. ( DeLorenzo, RJ; Rice, AC, 1998) |
| "Pilocarpine (PILO) induces in rats limbic seizures that become secondarily generalized and evolve to status epilepticus (SE)." | 3.69 | Effects of conventional antiepileptic drugs in a model of spontaneous recurrent seizures in rats. ( Cavalheiro, EA; Leite, JP, 1995) |
| "Pilocarpine (PILO) administered to rats acutely induces status epilepticus (acute period), which is followed by a transient seizure-free period (silent period), and finally by a chronic phase of spontaneous recurrent seizures (chronic period, SRS) that lasts for the rest of animal's life." | 3.69 | Profile of prostaglandin levels in the rat hippocampus in pilocarpine model of epilepsy. ( Bellíssimo, MI; Cavalheiro, EA; Naffah-Mazzacoratti, MG, 1995) |
| "Structural brain damage promoted by pilocarpine-induced status epilepticus may underlie or be associated with recurrent spontaneous seizures in mice." | 3.69 | The pilocarpine model of epilepsy in mice. ( Cavalheiro, EA; Priel, MR; Santos, NF, 1996) |
| "In the present study glutamate decarboxylase immunoreactivity (GAD-IR) was used to quantify GABAergic neurons in the hippocampus of rats exhibiting spontaneous recurrent seizures following pilocarpine-induced status epilepticus." | 3.68 | GAD-immunoreactive neurons are preserved in the hippocampus of rats with spontaneous recurrent seizures. ( Cavalheiro, EA, 1990) |
| "Seizures induced by pilocarpine (PILO) have proven to be a useful procedure for investigating the basic mechanisms essential for generation, spread and motor expression of seizures in rodents." | 3.68 | Spontaneous recurrent seizures in rats: an experimental model of partial epilepsy. ( Bortolotto, ZA; Cavalheiro, EA; Leite, JP, 1990) |
| " Pilocarpine was administered by a ramp-up dosing protocol that allows determining interindividual differences in susceptibility to the convulsant." | 1.43 | The pilocarpine model of temporal lobe epilepsy: Marked intrastrain differences in female Sprague-Dawley rats and the effect of estrous cycle. ( Bankstahl, M; Brandt, C; Klee, R; Löscher, W; Töllner, K, 2016) |
| "Bromodeoxyuridine (BrdU) was intraperitoneally administered 36h before the rats were sacrificed." | 1.34 | Consequences of pilocarpine-induced recurrent seizures in neonatal rats. ( Ji-Wen, W; Ruo-Peng, S; Xiu-Yu, S, 2007) |
| "The rats of seizure group were subjected to three times of pilocarpine injections intraperitonealy at postnatal day 1 (P1), 4 (P4) and 7 (P7)." | 1.33 | [Effects and consequence of recurrent seizures of neonatal rat on the hippocampal neurogenesis]. ( Shi, XY; Sun, RP; Wang, JW, 2006) |
| "Cycloheximide-treated animals differed from Pilo animals in the extent of hilar loss and supragranular mossy fiber sprouting as well as tissue shrinkage in the dorsal hippocampus." | 1.33 | Behavioral changes resulting from the administration of cycloheximide in the pilocarpine model of epilepsy. ( Blanco, MM; Dos Santos, JG; Longo, BM; Mello, LE; Menezes de Oliveira, MG, 2005) |
| "Drug design in epilepsy is now tackling a new target--epileptogenesis." | 1.33 | A spontaneous recurrent seizure bioassay for anti-epileptogenic molecules. ( Lyon, AP; Marone, S; Wainman, D; Weaver, DF, 2005) |
| "It is known that evoked seizures can increase neurogenesis in the dentate gyrus in adult rats." | 1.32 | Spontaneous recurrent seizure following status epilepticus enhances dentate gyrus neurogenesis. ( Akman, C; Cha, BH; Holmes, GL; Liu, X; Silveira, DC, 2004) |
| " In addition, long-term administration of high-dose topiramate in the normal developing rat brain does not appear to impair cognitive performance." | 1.31 | Effect of topiramate following recurrent and prolonged seizures during early development. ( Cha, BH; Holmes, GL; Hu, Y; Liu, X; Silveira, DC, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (15.56) | 18.7374 |
| 1990's | 7 (15.56) | 18.2507 |
| 2000's | 22 (48.89) | 29.6817 |
| 2010's | 9 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, X | 1 |
| Shangguan, Y | 1 |
| Lu, S | 1 |
| Wang, W | 1 |
| Du, C | 1 |
| Xiao, F | 1 |
| Hu, Y | 2 |
| Luo, J | 1 |
| Wang, L | 1 |
| He, C | 1 |
| Yang, Y | 1 |
| Zhang, Y | 1 |
| Lu, X | 1 |
| Yang, Q | 1 |
| Wang, X | 1 |
| Zhu, K | 1 |
| Yuan, B | 1 |
| Hu, M | 1 |
| Feng, GF | 1 |
| Liu, Y | 1 |
| Liu, JX | 1 |
| Liu, TT | 1 |
| Feng, L | 1 |
| Liu, HF | 1 |
| Shu, Y | 1 |
| Xiao, B | 1 |
| Hong, S | 1 |
| Xin, Y | 1 |
| HaiQin, W | 1 |
| GuiLian, Z | 1 |
| Ru, Z | 1 |
| ShuQin, Z | 1 |
| HuQing, W | 1 |
| Li, Y | 1 |
| Ning, B | 1 |
| YongNan, L | 1 |
| Orban, BO | 1 |
| Routh, VH | 1 |
| Levin, BE | 1 |
| Berlin, JR | 1 |
| Brandt, C | 1 |
| Bankstahl, M | 1 |
| Töllner, K | 1 |
| Klee, R | 1 |
| Löscher, W | 1 |
| Trindade-Filho, EM | 1 |
| de Castro-Neto, EF | 1 |
| de A Carvalho, R | 1 |
| Lima, E | 1 |
| Scorza, FA | 2 |
| Amado, D | 1 |
| Naffah-Mazzacoratti, Mda G | 1 |
| Cavalheiro, EA | 8 |
| Biagini, G | 2 |
| Longo, D | 2 |
| Baldelli, E | 1 |
| Zoli, M | 1 |
| Rogawski, MA | 1 |
| Bertazzoni, G | 1 |
| Avoli, M | 1 |
| Prasad, S | 1 |
| Baccon, J | 1 |
| Galetta, SL | 1 |
| Furtado, MA | 1 |
| Castro, OW | 1 |
| Del Vecchio, F | 1 |
| de Oliveira, JA | 1 |
| Garcia-Cairasco, N | 1 |
| Gualtieri, F | 1 |
| Marinelli, C | 1 |
| Pugnaghi, M | 1 |
| Nichelli, PF | 1 |
| Meletti, S | 1 |
| Jayaram, B | 1 |
| Khan, RS | 1 |
| Kastin, AJ | 1 |
| Hsuchou, H | 1 |
| Wu, X | 1 |
| Pan, W | 1 |
| Zhang, X | 1 |
| Cui, SS | 1 |
| Wallace, AE | 1 |
| Hannesson, DK | 1 |
| Schmued, LC | 1 |
| Saucier, DM | 1 |
| Honer, WG | 1 |
| Corcoran, ME | 1 |
| Arida, RM | 3 |
| Priel, M | 1 |
| Calderazzo, L | 1 |
| Cha, BH | 2 |
| Silveira, DC | 2 |
| Liu, X | 2 |
| Holmes, GL | 3 |
| Gowda, V | 1 |
| Roberts, M | 1 |
| Wolfe, R | 1 |
| Klaustermeyer, WB | 1 |
| Lyon, A | 1 |
| Marone, S | 2 |
| Wainman, D | 2 |
| Weaver, DF | 2 |
| Akman, C | 1 |
| Hoffmann, AF | 1 |
| Zhao, Q | 1 |
| Lyon, AP | 1 |
| Peng, Z | 1 |
| Houser, CR | 1 |
| Dos Santos, JG | 1 |
| Longo, BM | 1 |
| Blanco, MM | 1 |
| Menezes de Oliveira, MG | 1 |
| Mello, LE | 1 |
| Shi, XY | 1 |
| Wang, JW | 1 |
| Sun, RP | 1 |
| Xiu-Yu, S | 1 |
| Ruo-Peng, S | 1 |
| Ji-Wen, W | 1 |
| Reime Kinjo, E | 1 |
| Mara de Oliveira, D | 1 |
| da Silva Fernandes, MJ | 1 |
| Goffin, K | 1 |
| Nissinen, J | 1 |
| Van Laere, K | 1 |
| Pitkänen, A | 1 |
| Sharma, AK | 1 |
| Reams, RY | 1 |
| Jordan, WH | 1 |
| Miller, MA | 1 |
| Thacker, HL | 1 |
| Snyder, PW | 1 |
| Schipper, I | 1 |
| Leite, JP | 2 |
| Naffah-Mazzacoratti, MG | 1 |
| Bellíssimo, MI | 1 |
| Santos, NF | 1 |
| Priel, MR | 2 |
| Wasterlain, CG | 1 |
| Rice, AC | 1 |
| DeLorenzo, RJ | 1 |
| dos Santos, NF | 1 |
| Filho, EM | 1 |
| André, V | 1 |
| Marescaux, C | 1 |
| Nehlig, A | 1 |
| Fritschy, JM | 1 |
| Scharfman, HE | 1 |
| Sollas, AL | 1 |
| Goodman, JH | 1 |
| Berkeley, JL | 1 |
| Decker, MJ | 1 |
| Levey, AI | 1 |
| Huismans, H | 1 |
| Bortolotto, ZA | 1 |
| Gray, RH | 1 |
| Nairne, JH | 1 |
| Ayliffe, WH | 1 |
| Melamed, S | 1 |
| Wagoner, MD | 1 |
| Lowe, RF | 1 |
| Kennedy, RE | 1 |
| Roca, PD | 1 |
| Platt, DS | 1 |
| Bedrossian, RH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Dual Frequency, Dual Region Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease[NCT04650932] | 10 participants (Anticipated) | Interventional | 2022-10-22 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for pilocarpine and Recrudescence
| Article | Year |
|---|---|
Mesial temporal lobe epilepsy: pathogenesis, induced rodent models and lesions.
Topics: Animals; Disease Models, Animal; Electric Stimulation; Epilepsy, Temporal Lobe; Fever; Hippocampus; | 2007 |
Recurrent seizures in the developing brain are harmful.
Topics: Adult; Animals; Brain; Brain Injuries; Child; Disease Models, Animal; Entorhinal Cortex; Epilepsy; H | 1997 |
43 other studies available for pilocarpine and Recrudescence
| Article | Year |
|---|---|
Tubulin β-III modulates seizure activity in epilepsy.
Topics: Adolescent; Adult; Animals; Child; Down-Regulation; Electroencephalography; Female; Hippocampus; Hum | 2017 |
Reduced abnormal integration of adult-generated granule cells does not attenuate spontaneous recurrent seizures in mice.
Topics: Animals; Bromodeoxyuridine; Cell Count; Disease Models, Animal; Doublecortin Domain Proteins; Female | 2017 |
Altered axon initial segment in hippocampal newborn neurons, associated with recurrence of temporal lobe epilepsy in rats.
Topics: Animals; Axon Initial Segment; Behavior, Animal; Cell Proliferation; Chronic Disease; Dendrites; Den | 2017 |
The PPARγ agonist rosiglitazone prevents neuronal loss and attenuates development of spontaneous recurrent seizures through BDNF/TrkB signaling following pilocarpine-induced status epilepticus.
Topics: Animals; Anticonvulsants; Brain-Derived Neurotrophic Factor; Electroencephalography; Enzyme-Linked I | 2013 |
Direct effects of recurrent hypoglycaemia on adrenal catecholamine release.
Topics: Acetylcholine; Adrenal Glands; Animals; Blood Glucose; Cholinergic Agonists; Disease Models, Animal; | 2015 |
The pilocarpine model of temporal lobe epilepsy: Marked intrastrain differences in female Sprague-Dawley rats and the effect of estrous cycle.
Topics: Animals; Behavior, Animal; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; El | 2016 |
Serotonin depletion effects on the pilocarpine model of epilepsy.
Topics: 5,7-Dihydroxytryptamine; Acute Disease; Animals; Behavior, Animal; Chronic Disease; Disease Models, | 2008 |
Neurosteroids and epileptogenesis in the pilocarpine model: evidence for a relationship between P450scc induction and length of the latent period.
Topics: Animals; Cholesterol Side-Chain Cleavage Enzyme; Disease Models, Animal; Enzyme Induction; Male; Neu | 2009 |
Mydriatic pupil in giant cell arteritis.
Topics: Aged, 80 and over; Amaurosis Fugax; Anisocoria; Dermatomyositis; Diabetes Complications; Ganglia, Pa | 2009 |
Study of spontaneous recurrent seizures and morphological alterations after status epilepticus induced by intrahippocampal injection of pilocarpine.
Topics: Animals; Axons; Behavior, Animal; Brain; Chi-Square Distribution; Disease Models, Animal; Fluorescei | 2011 |
Hypoxia markers are expressed in interneurons exposed to recurrent seizures.
Topics: Animals; Anticonvulsants; Biomarkers; Cell Hypoxia; Cerebral Cortex; Convulsants; Diazepam; Disease | 2013 |
Protective role of astrocytic leptin signaling against excitotoxicity.
Topics: Animals; Astrocytes; Astrocytoma; Cell Line, Tumor; Convulsants; Epilepsy; Female; Gene Expression R | 2013 |
Relations between brain pathology and temporal lobe epilepsy.
Topics: Animals; Brain; Cell Death; Cell Survival; Chronic Disease; Disease Models, Animal; Disease Progress | 2002 |
The contribution of the lateral posterior and anteroventral thalamic nuclei on spontaneous recurrent seizures in the pilocarpine model of epilepsy.
Topics: Animals; Anterior Thalamic Nuclei; Behavior, Animal; Disease Models, Animal; Male; Muscarinic Agonis | 2002 |
Effect of topiramate following recurrent and prolonged seizures during early development.
Topics: Animals; Animals, Newborn; Anticonvulsants; Body Weight; Cell Death; Cognition; Convulsants; Disease | 2002 |
Recurrent cough and normal sweat chloride test.
Topics: Adolescent; Bronchiectasis; Cough; Cystic Fibrosis; Diagnosis, Differential; Forced Expiratory Volum | 2003 |
Implementing a bioassay to screen molecules for antiepileptogenic activity: chronic pilocarpine versus subdudral haematoma models.
Topics: Animals; Chronic Disease; Disease Models, Animal; Electroencephalography; Epilepsy; Hematoma, Subdur | 2004 |
Spontaneous recurrent seizure following status epilepticus enhances dentate gyrus neurogenesis.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Division; Dentate Gyrus; Disease Models, Anim | 2004 |
Cognitive impairment following status epilepticus and recurrent seizures during early development: support for the "two-hit hypothesis".
Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Cell Death; Cognition Disorders; | 2004 |
A spontaneous recurrent seizure bioassay for anti-epileptogenic molecules.
Topics: Animals; Anticonvulsants; Biological Assay; Disease Models, Animal; Drug Evaluation, Preclinical; Ep | 2005 |
Temporal patterns of fos expression in the dentate gyrus after spontaneous seizures in a mouse model of temporal lobe epilepsy.
Topics: Animals; Dentate Gyrus; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hi | 2005 |
Behavioral changes resulting from the administration of cycloheximide in the pilocarpine model of epilepsy.
Topics: Acoustic Stimulation; Animals; Anxiety; Behavior, Animal; Cell Count; Conditioning, Psychological; C | 2005 |
[Effects and consequence of recurrent seizures of neonatal rat on the hippocampal neurogenesis].
Topics: Age Factors; Animals; Animals, Newborn; Bromodeoxyuridine; Hippocampus; Neurogenesis; Pilocarpine; R | 2006 |
Consequences of pilocarpine-induced recurrent seizures in neonatal rats.
Topics: Animals; Animals, Newborn; Antimetabolites; Benzoxazines; Brain; Bromodeoxyuridine; Cell Proliferati | 2007 |
The Na+/K+ATPase activity is increased in the hippocampus after multiple status epilepticus induced by pilocarpine in developing rats.
Topics: Aging; Animals; Animals, Newborn; Hippocampus; Pilocarpine; Rats; Rats, Wistar; Recurrence; Sodium-P | 2007 |
Cyclicity of spontaneous recurrent seizures in pilocarpine model of temporal lobe epilepsy in rat.
Topics: Animals; Behavior, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Male; Muscarinic Agonist | 2007 |
[A case of recurrent hyphema in pseudophakia].
Topics: Aged; Humans; Hyphema; Lenses, Intraocular; Male; Pilocarpine; Postoperative Complications; Recurren | 1984 |
Effects of conventional antiepileptic drugs in a model of spontaneous recurrent seizures in rats.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Complex Partial; | 1995 |
Profile of prostaglandin levels in the rat hippocampus in pilocarpine model of epilepsy.
Topics: Animals; Dinoprost; Dinoprostone; Disease Models, Animal; Epilepsy; Hippocampus; Male; Muscarinic Ag | 1995 |
The pilocarpine model of epilepsy in mice.
Topics: Animals; Coloring Agents; Dentate Gyrus; Disease Models, Animal; Electroencephalography; Epilepsy; E | 1996 |
NMDA receptor activation during status epilepticus is required for the development of epilepsy.
Topics: Animals; Cell Count; Dizocilpine Maleate; Electroencephalography; Epilepsy; Excitatory Amino Acid An | 1998 |
Epileptogenesis in immature rats following recurrent status epilepticus.
Topics: Age Factors; Animals; Anxiety; Avoidance Learning; Brain; Electroencephalography; Exploratory Behavi | 2000 |
Alterations of hippocampal GAbaergic system contribute to development of spontaneous recurrent seizures in the rat lithium-pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Lithium; Neuro | 2001 |
Spontaneous recurrent seizures after pilocarpine-induced status epilepticus activate calbindin-immunoreactive hilar cells of the rat dentate gyrus.
Topics: Animals; Calbindins; Cell Count; Dentate Gyrus; Male; Neurons; Neuropeptide Y; Parvalbumins; Pilocar | 2002 |
The role of muscarinic acetylcholine receptor-mediated activation of extracellular signal-regulated kinase 1/2 in pilocarpine-induced seizures.
Topics: Aminoacetonitrile; Animals; Blotting, Western; Cell Death; Disease Models, Animal; Enzyme Activation | 2002 |
[The treatment of posner-schlossmann's syndrome. (acute glaucomatocyclitic crises) (author's transl)].
Topics: Acetazolamide; Adult; Cortisone; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pr | 1975 |
GAD-immunoreactive neurons are preserved in the hippocampus of rats with spontaneous recurrent seizures.
Topics: Animals; Epilepsies, Partial; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Male; N | 1990 |
Spontaneous recurrent seizures in rats: an experimental model of partial epilepsy.
Topics: Aggression; Amygdala; Animals; Behavior, Animal; Cerebral Cortex; Disease Models, Animal; Electroenc | 1990 |
Efficacy of Nd-YAG laser iridotomies in acute angle closure glaucoma.
Topics: Glaucoma; Humans; Iris; Laser Therapy; Phenylephrine; Pilocarpine; Postoperative Complications; Recu | 1989 |
Recurrent closure of neodymium: YAG laser iridotomies requiring multiple treatments in pseudophakic pupillary block.
Topics: Cataract Extraction; Dexamethasone; Humans; Iris; Iris Diseases; Laser Therapy; Male; Middle Aged; P | 1988 |
Persistent symptoms after peripheral iridectomy for angle-closure glaucoma.
Topics: Acute Disease; Adult; Aged; Female; Glaucoma; Humans; Intraocular Pressure; Iris; Middle Aged; Pain; | 1987 |
Further observations on atypical band keratopathy in glaucoma patients.
Topics: Aged; Calcium; Cornea; Corneal Opacity; Edetic Acid; Glaucoma; Histocytochemistry; Humans; Iron; Mem | 1974 |
The management of traumatic hyphema.
Topics: Atropine; Bandages; Eye Injuries; Humans; Hyphema; Iris; Methods; Miotics; Mydriatics; Ointments; Pi | 1974 |