Page last updated: 2024-11-07

pilocarpine and Pregnancy

pilocarpine has been researched along with Pregnancy in 70 studies

Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
" Thereafter, pilocarpine was administered, and significant differences in susceptibility to seizures were detected depending on the degree of brain dysplasia."7.96Changes of EEG spectra in rat brains with different patterns of dysplasia in response to pilocarpine-induced seizures. ( Gzieło, K; Janeczko, K; Kiełbinski, M; Setkowicz, Z; Węglarz, W, 2020)
" We found that rats previously subjected to lithium-pilocarpine (LiPC)-induced neonatal status epilepticus (NeoSE) exhibited enhanced behavioral sensitization to methamphetamine (MA) in adolescence."7.75Neonatal status epilepticus alters prefrontal-striatal circuitry and enhances methamphetamine-induced behavioral sensitization in adolescence. ( Chen, GS; Huang, LT; Huang, YN; Lin, TC; Wang, JY, 2009)
" Here, we investigated the effects of antazoline on NMDA toxicity and current in rat hippocampal neuronal cultures, and on an in vivo model of status epilepticus."7.72Neuroprotective activity of antazoline against neuronal damage induced by limbic status epilepticus. ( Bockaert, J; Lafon-Cazal, M; Lerner-Natoli, M; Milhaud, D; Rondouin, G, 2003)
"To determine whether brains irradiated at different stages of prenatal development also have different postnatal susceptibility to seizures evoked by pilocarpine."7.72Long-term changes in postnatal susceptibility to pilocarpine-induced seizures in rats exposed to gamma radiation at different stages of prenatal development. ( Janeczko, K; Kłak, K; Setkowicz, Z, 2003)
"Motor manifestations of seizure activity were observed continuously for 6 hours and rated."5.33Brains with different degrees of dysplasia show different patterns of neurodegenerative changes following pilocarpine-induced seizures. Histologic evidence of tissue damage correlated with MRI data. ( Janeczko, K; Janicka, D; Jasiński, A; Majcher, K; Setkowicz, Z; Skórka, T; Sułek, Z, 2006)
" Thereafter, pilocarpine was administered, and significant differences in susceptibility to seizures were detected depending on the degree of brain dysplasia."3.96Changes of EEG spectra in rat brains with different patterns of dysplasia in response to pilocarpine-induced seizures. ( Gzieło, K; Janeczko, K; Kiełbinski, M; Setkowicz, Z; Węglarz, W, 2020)
"To elucidate the impact of maternal seizures in the developing rat brain, pregnant Wistar rats were subjected to the pilocarpine-induced seizures and pups from different litters were studied at different ages."3.83Maternal seizures can affect the brain developing of offspring. ( Amado, D; Cossa, AC; da Graça Naffah-Mazzacoratti, M; da Silva Fernandes, MJ; de Alencar Rocha, AK; do Vale, TG; Lima, DC, 2016)
"To evaluate a potential insult in the cerebellum of pups exposed to maternal epileptic seizures during intrauterine life, female rats were subjected to pilocarpine-induced epilepsy."3.77Neuroglobin is up-regulated in the cerebellum of pups exposed to maternal epileptic seizures. ( Amado, D; Cavalheiro, EA; Cossa, AC; da Graça Naffah-Mazzacoratti, M; da Silva Fernandes, MJ; da Silva, IR; da Silva, JA; de Oliveira, EM; Higa, EM; Lima, DC; Perosa, SR, 2011)
" An epilepsy model was induced in female rats by administration of pilocarpine."3.76Behavioral evaluation of adult rats exposed in utero to maternal epileptic seizures. ( Amado, D; Arganãraz, GA; Cavalheiro, EA; Frussa-Filho, R; Lima, DC; Naffah-Mazzacoratti, Mda G; Vale, TG; Varella, PP, 2010)
" We found that rats previously subjected to lithium-pilocarpine (LiPC)-induced neonatal status epilepticus (NeoSE) exhibited enhanced behavioral sensitization to methamphetamine (MA) in adolescence."3.75Neonatal status epilepticus alters prefrontal-striatal circuitry and enhances methamphetamine-induced behavioral sensitization in adolescence. ( Chen, GS; Huang, LT; Huang, YN; Lin, TC; Wang, JY, 2009)
"In the present study, we explored the consequences of epilepsy on the neurobehavioral development of the offspring in a rat model of spontaneous epilepsy, the lithium-pilocarpine model of temporal lobe epilepsy not dependent on genetic factors and in animals not receiving any antiepileptic treatment."3.75Neurobehavioral maturation of offspring from epileptic dams: study in the rat lithium-pilocarpine model. ( Boehrer, A; de Vasconcelos, AP; Desor, D; Nehlig, A; Raffo, E, 2009)
" Proneurotrophins, which are potent apoptosis-inducing ligands for p75(NTR), were increased in the hippocampus, particularly in astrocytes, by pilocarpine-induced seizures; and infusion of anti-pro-NGF dramatically attenuated neuronal loss after seizures."3.74Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures. ( Carter, BD; Cragnolini, A; Friedman, WJ; Hempstead, BL; Kenchappa, RS; Light, M; Trotter, C; Volosin, M, 2008)
" Here, we investigated the effects of antazoline on NMDA toxicity and current in rat hippocampal neuronal cultures, and on an in vivo model of status epilepticus."3.72Neuroprotective activity of antazoline against neuronal damage induced by limbic status epilepticus. ( Bockaert, J; Lafon-Cazal, M; Lerner-Natoli, M; Milhaud, D; Rondouin, G, 2003)
"To determine whether brains irradiated at different stages of prenatal development also have different postnatal susceptibility to seizures evoked by pilocarpine."3.72Long-term changes in postnatal susceptibility to pilocarpine-induced seizures in rats exposed to gamma radiation at different stages of prenatal development. ( Janeczko, K; Kłak, K; Setkowicz, Z, 2003)
" In a second case report we describe, in a 61-year-old patient suffering from aspirin-sensitive asthma, recurrent ciliary body oedema with a marked spastic component which was triggered by the medications acetazolamide, dipivefrine and pilocarpine."3.69Drug-induced ciliary body oedema: a new theory. ( Krieg, PH; Schipper, I, 1996)
"Cortical dysplasia is the most common etiology of intractable epilepsy."1.48Axon Initial Segment Structural Plasticity is Involved in Seizure Susceptibility in a Rat Model of Cortical Dysplasia. ( Feng, L; Wang, YL; Xiao, B; Yue, ZW, 2018)
"At postnatal day 45, seizure susceptibility was assessed in response to lithium-pilocarpine (LiPC) in adult offspring."1.39Prenatal immune challenge in rats increases susceptibility to seizure-induced brain injury in adulthood. ( Huang, SY; Li, BM; Li, Z; Liu, J; Qiao, NN; Sun, RP; Wang, YY; Yin, P, 2013)
"Animals exposed to seizures in utero showed impaired social behavior with no signs of anxiety-like behavior."1.38Social behavior impairment in offspring exposed to maternal seizures in utero. ( Amado, D; Cysneiros, RM; Novaes, GF; Scorza, FA, 2012)
"Pilocarpine was administered on postnatal day 25 and mortality rates were measured after 2 and 24h."1.37Prenatal exposure to restraint or predator stresses attenuates field excitatory postsynaptic potentials in infant rats. ( Ahmadzadeh, R; Roshan-Milani, S; Saboory, E, 2011)
"We investigated the effect of epileptic seizures during pregnancy on hippocampal expression of calcium-binding proteins in the offspring."1.36Seizures during pregnancy modify the development of hippocampal interneurons of the offspring. ( Amado, D; Cabral, FR; Cavalheiro, EA; Cossa, AC; da Silva, AV; de Lima, E; de Oliveira, EM; do Vale, TG; Lima, DC; Naffah-Mazzacoratti, Mda G; Torres, LB, 2010)
"Motor manifestations of seizure activity were observed continuously for 6 hours and rated."1.33Brains with different degrees of dysplasia show different patterns of neurodegenerative changes following pilocarpine-induced seizures. Histologic evidence of tissue damage correlated with MRI data. ( Janeczko, K; Janicka, D; Jasiński, A; Majcher, K; Setkowicz, Z; Skórka, T; Sułek, Z, 2006)
" Over the oral dosage range studied, i."1.32Absorption, distribution and excretion of 14C-pilocarpine following oral administration to rats. ( Chasseaud, LF; Endo, T; Hara, Y; John, AJ; John, BA; McBurney, A; Midgley, I; Nishiyama, M; Omori, Y; Smart, CI, 2004)
"Choline is an essential nutrient for rats and humans, and its availability during fetal development has long-lasting cognitive effects (Blusztajn, 1998)."1.31Protective effects of prenatal choline supplementation on seizure-induced memory impairment. ( Blusztajn, JK; Cermak, JM; Holmes, GL; Liu, Z; Neill, JC; Sarkisian, MR; Stafstrom, CE; Tandon, P; Yang, Y, 2000)
"Acute angle closure glaucoma generally occurs in older hypermetropic individuals, precipitated by pupillary dilation."1.28Angle closure glaucoma precipitated by labour. ( Dhillon, BJ; Kearns, PP, 1990)
"Pilocarpine is a muscarinic agonist that readily crosses the blood-brain barrier and was therefore employed to examine both central and peripheral muscarinic mechanisms in modulating fetal cardiovascular function."1.28Central muscarinic modulation of fetal blood pressure and heart rate. ( Hinman, DJ; Szeto, HH, 1990)
"Hemorrhagic atelectasis was successfully produced in newborn rabbits by pharmacologically narrowing airways leading to alveoli ventilated with oxygen-enriched gas."1.25A new model for neonatal pulmonary hemorrhage research. ( Kotas, RV; Mims, LC; Trainor, EJ; Wells, TJ; Wiles, CL, 1975)

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-199030 (42.86)18.7374
1990's7 (10.00)18.2507
2000's16 (22.86)29.6817
2010's15 (21.43)24.3611
2020's2 (2.86)2.80

Authors

AuthorsStudies
Setkowicz, Z4
Kiełbinski, M1
Gzieło, K1
Węglarz, W1
Janeczko, K4
Pacheco, ALD1
de Melo, IS1
de Souza, FMA1
Nicácio, DCSP1
Freitas-Santos, J1
Oliveira Dos Santos, YM1
Costa, MA1
Cavalcante, CMB1
Gomes Dos Santos Neto, J1
Gitaí, DLG1
Sabino-Silva, R1
Torres de Miranda, C1
Borbely, AU1
Duzzioni, M1
Shetty, AK1
de Castro, OW1
Yue, ZW1
Wang, YL1
Xiao, B1
Feng, L1
Nejatbakhsh, M1
Saboory, E4
Bagheri, M1
Colciaghi, F1
Nobili, P1
Cipelletti, B1
Cagnoli, C1
Zambon, S1
Locatelli, D1
de Curtis, M1
Battaglia, GS1
Yin, P1
Liu, J1
Li, Z1
Wang, YY1
Qiao, NN1
Huang, SY1
Li, BM1
Sun, RP1
Pourmotabbed, A1
Mahmoodi, G1
Mahmoodi, S1
Mohammadi-Farani, A1
Nedaei, SE1
Pourmotabbed, T2
Fu, Y1
Yang, MS1
Jiang, J1
Ganesh, T1
Joe, E1
Dingledine, R1
Cossa, AC3
Lima, DC4
do Vale, TG2
de Alencar Rocha, AK1
da Graça Naffah-Mazzacoratti, M2
da Silva Fernandes, MJ2
Amado, D6
Volosin, M1
Trotter, C1
Cragnolini, A1
Kenchappa, RS1
Light, M1
Hempstead, BL1
Carter, BD1
Friedman, WJ1
Lin, TC1
Huang, LT1
Huang, YN1
Chen, GS1
Wang, JY1
Raffo, E2
de Vasconcelos, AP1
Boehrer, A1
Desor, D1
Nehlig, A4
Vale, TG1
Arganãraz, GA1
Varella, PP1
Frussa-Filho, R1
Cavalheiro, EA4
Naffah-Mazzacoratti, Mda G2
Sadaghiani, MM1
da Silva, AV1
de Lima, E1
Torres, LB1
de Oliveira, EM2
Cabral, FR1
Ahmadzadeh, R2
Roshan-Milani, S2
Pilehvarian, AA1
Perosa, SR1
da Silva, JA1
da Silva, IR1
Higa, EM1
Novaes, GF1
Scorza, FA1
Cysneiros, RM1
Peixoto, RT1
Kunz, PA1
Kwon, H1
Mabb, AM1
Sabatini, BL1
Philpot, BD1
Ehlers, MD1
Milhaud, D1
Rondouin, G1
Lerner-Natoli, M1
Bockaert, J1
Lafon-Cazal, M1
DZOLJIC, M1
HUNTER, RL1
ROCHA, JT1
PFRENDER, AR1
DEJONG, DC1
KULLANDER, S1
SONESSON, B1
Kłak, K1
Omori, Y1
Endo, T1
Hara, Y1
Nishiyama, M1
Midgley, I1
Smart, CI1
John, AJ1
Chasseaud, LF1
McBurney, A1
John, BA1
Koning, E1
Guvendag Guven, ES1
Guven, S1
Coskun, F1
Ayhan, A1
Sener, C1
Choi, IS1
Cho, JH1
Lee, MG1
Choi, BJ1
Janicka, D2
Kowalczyk, A1
Turlej, A1
Leung, DY1
Fok, AC1
Lam, DS1
Ding, C1
Chang, N1
Fong, YC1
Wang, Y1
Trousdale, MD1
Mircheff, AK1
Schechter, JE1
Majcher, K1
Sułek, Z1
Skórka, T1
Jasiński, A1
St-Pierre, LS1
Parker, GH1
Bubenik, GA1
Persinger, MA1
Jansen, AH1
Ioffe, S1
Chernick, V1
Smith, DM3
Shelley, SA3
Balis, JU3
Brus, R1
Kostrzewa, RM2
Perry, KW1
Fuller, RW1
Neely, D1
Krieg, PH1
Schipper, I1
Dubé, C2
André, V1
Covolan, L1
Ferrandon, A1
Marescaux, C2
Boyet, S1
Yang, Y1
Liu, Z1
Cermak, JM1
Tandon, P1
Sarkisian, MR1
Stafstrom, CE1
Neill, JC1
Blusztajn, JK1
Holmes, GL1
Konstantinov, P2
Radoslavov, V1
Clemett, RS1
Corbet, AJ2
Flax, P2
Rudolph, AJ2
Kotas, RV1
Wells, TJ1
Mims, LC1
Trainor, EJ1
Wiles, CL1
Kearns, PP1
Dhillon, BJ1
Szeto, HH2
Hinman, DJ2
Blackshaw, JK1
Blackshaw, AW1
Oettling, G1
Schmidt, H1
Drews, U1
Castellano, C1
Moreno, M1
Raggi, LA1
Martinez de Victoria, E1
Mataix, FJ1
Watanabe, T1
Matsuhashi, K1
Takayama, S1
Lindstrom, LH3
Meyerson, BJ2
Carrer, H1
Eliasson, M1
Kuga, T1
Naito, J1
Kawahara, Y1
Yamada, S1
Pauerstein, CJ1
Woodruff, JD1
Zachary, AS1
Cseh, S1
Niebrój, T1
Gierek, A1
Samochowiec, E1
Birks, DA1
Prior, VJ1
Silk, E1
Whittaker, M1
Rosenow, EC1
Lee, RA1
Gebala, A1
Zytkiewicz, A1

Reviews

1 review available for pilocarpine and Pregnancy

ArticleYear
Factors influencing physiologic activities in the fallopian tube; the anatomy, physiology, and pharmacology of tubal transport.
    Obstetrical & gynecological survey, 1968, Volume: 23, Issue:3

    Topics: Acetylcholine; Contracture; Epinephrine; Ergot Alkaloids; Estrogens; Fallopian Tubes; Female; Humans

1968

Other Studies

69 other studies available for pilocarpine and Pregnancy

ArticleYear
Changes of EEG spectra in rat brains with different patterns of dysplasia in response to pilocarpine-induced seizures.
    Epilepsy & behavior : E&B, 2020, Volume: 111

    Topics: Animals; Brain; Electroencephalography; Female; Gamma Rays; Male; Malformations of Cortical Developm

2020
Maternal crack cocaine use in rats leads to depressive- and anxiety-like behavior, memory impairment, and increased seizure susceptibility in the offspring.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2021, Volume: 44

    Topics: Animals; Anxiety; Cocaine-Related Disorders; Crack Cocaine; Epilepsy; Female; Male; Memory Disorders

2021
Axon Initial Segment Structural Plasticity is Involved in Seizure Susceptibility in a Rat Model of Cortical Dysplasia.
    Neurochemical research, 2018, Volume: 43, Issue:4

    Topics: Animals; Axon Initial Segment; Axons; Disease Models, Animal; Disease Susceptibility; Electroencepha

2018
Effect of prenatal stress on ɑ5 GABA
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2018, Volume: 68

    Topics: Animals; Animals, Newborn; Disease Models, Animal; Female; Gene Expression Regulation, Developmental

2018
Targeting PSD95-nNOS interaction by Tat-N-dimer peptide during status epilepticus is neuroprotective in MAM-pilocarpine rat model.
    Neuropharmacology, 2019, 07-15, Volume: 153

    Topics: Animals; Disease Models, Animal; Disks Large Homolog 4 Protein; Female; Methylazoxymethanol Acetate;

2019
Prenatal immune challenge in rats increases susceptibility to seizure-induced brain injury in adulthood.
    Brain research, 2013, Jun-26, Volume: 1519

    Topics: Age Factors; Animals; Animals, Newborn; Brain Injuries; Disease Models, Animal; Disease Susceptibili

2013
Effect of central muscarinic receptors on passive-avoidance learning deficits induced by prenatal pentylenetetrazol kindling in male offspring.
    Neuroscience, 2014, Oct-24, Volume: 279

    Topics: Animals; Avoidance Learning; Brain; Female; Kindling, Neurologic; Learning Disabilities; Male; Musca

2014
EP2 Receptor Signaling Regulates Microglia Death.
    Molecular pharmacology, 2015, Volume: 88, Issue:1

    Topics: Alprostadil; Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Female; Gene Expression Re

2015
Maternal seizures can affect the brain developing of offspring.
    Metabolic brain disease, 2016, Volume: 31, Issue:4

    Topics: Animals; bcl-2-Associated X Protein; Blood Glucose; Female; Hippocampus; Male; Pilocarpine; Poly (AD

2016
Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Sep-24, Volume: 28, Issue:39

    Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Disease Models, Animal; DNA-Binding Proteins; El

2008
Neonatal status epilepticus alters prefrontal-striatal circuitry and enhances methamphetamine-induced behavioral sensitization in adolescence.
    Epilepsy & behavior : E&B, 2009, Volume: 14, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Corpus Striatum; Disease Models, Animal; D

2009
Neurobehavioral maturation of offspring from epileptic dams: study in the rat lithium-pilocarpine model.
    Experimental neurology, 2009, Volume: 219, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Antipsychotic Agents; Behavior, Animal; Body Weight; Chi-Squ

2009
Behavioral evaluation of adult rats exposed in utero to maternal epileptic seizures.
    Epilepsy & behavior : E&B, 2010, Volume: 18, Issue:1-2

    Topics: Animals; Anxiety; Behavior, Animal; Depression; Epilepsy; Female; Male; Motor Activity; Pilocarpine;

2010
Prenatal stress potentiates pilocarpine-induced epileptic behaviors in infant rats both time and sex dependently.
    Epilepsy & behavior : E&B, 2010, Volume: 18, Issue:3

    Topics: Analysis of Variance; Animals; Animals, Newborn; Corticosterone; Disease Models, Animal; Epilepsy; F

2010
Seizures during pregnancy modify the development of hippocampal interneurons of the offspring.
    Epilepsy & behavior : E&B, 2010, Volume: 19, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Calcium-Binding Proteins; Cell Count; Disease Models, Animal

2010
Predator and restraint stress during gestation facilitates pilocarpine-induced seizures in prepubertal rats.
    Developmental psychobiology, 2011, Volume: 53, Issue:8

    Topics: Animals; Animals, Newborn; Cats; Cholinergic Agents; Corticosterone; Female; Male; Pilocarpine; Pred

2011
Neuroglobin is up-regulated in the cerebellum of pups exposed to maternal epileptic seizures.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2011, Volume: 29, Issue:8

    Topics: Animals; Animals, Newborn; Cerebellum; Epilepsy; Female; Glial Fibrillary Acidic Protein; Globins; H

2011
Prenatal exposure to restraint or predator stresses attenuates field excitatory postsynaptic potentials in infant rats.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2011, Volume: 29, Issue:8

    Topics: Animals; Corticosterone; Electrophysiology; Excitatory Postsynaptic Potentials; Female; Gestational

2011
Social behavior impairment in offspring exposed to maternal seizures in utero.
    Journal of neural transmission (Vienna, Austria : 1996), 2012, Volume: 119, Issue:6

    Topics: Animals; Anxiety; Convulsants; Epilepsy, Tonic-Clonic; Female; Male; Pilocarpine; Pregnancy; Pregnan

2012
Transsynaptic signaling by activity-dependent cleavage of neuroligin-1.
    Neuron, 2012, Oct-18, Volume: 76, Issue:2

    Topics: Animals; Animals, Newborn; Biotinylation; Calcium-Binding Proteins; Cell Adhesion Molecules, Neurona

2012
Neuroprotective activity of antazoline against neuronal damage induced by limbic status epilepticus.
    Neuroscience, 2003, Volume: 120, Issue:2

    Topics: Animals; Animals, Newborn; Antazoline; Cell Count; Cells, Cultured; Cerebral Cortex; Disease Models,

2003
ACTION OF GUANETHIDINE ON SMOOTH MUSCLE OF GUINEA PIG, RAT, RABBIT, AND LEECH DORSAL MUSCLE.
    Archives internationales de pharmacodynamie et de therapie, 1964, Oct-01, Volume: 151

    Topics: Acetylcholine; Animals; Barium; Bradykinin; Carbachol; Epinephrine; Female; Guanethidine; Guinea Pig

1964
THE IMPACT OF GEL ELECTROPHORESIS UPON OUR UNDERSTANDING OF THE ESTERASES.
    Annals of the New York Academy of Sciences, 1964, Dec-28, Volume: 121

    Topics: Aging; Animals; Blood; Blood Proteins; Duodenum; Electrophoresis; Esterases; Female; Hepatectomy; Li

1964
STUDIES ON SALIVA IN MENSTRUATING, PREGNANT AND POST-MENOPAUSAL WOMEN.
    Acta endocrinologica, 1965, Volume: 48

    Topics: Crystallization; Female; Histamine; Humans; Menopause; Menstruation; Pharmacology; Pilocarpine; Preg

1965
Long-term changes in postnatal susceptibility to pilocarpine-induced seizures in rats exposed to gamma radiation at different stages of prenatal development.
    Epilepsia, 2003, Volume: 44, Issue:10

    Topics: Animals; Animals, Newborn; Brain; Female; Gamma Rays; Male; Pilocarpine; Pregnancy; Prenatal Exposur

2003
Absorption, distribution and excretion of 14C-pilocarpine following oral administration to rats.
    Arzneimittel-Forschung, 2004, Volume: 54, Issue:3

    Topics: Administration, Oral; Animals; Bile; Female; Injections, Intravenous; Intestinal Absorption; Male; M

2004
Postnatal maturation of cytochrome oxidase and lactate dehydrogenase activity and age-dependent consequences of lithium-pilocarpine status epilepticus in the rat: a regional histoenzymology study.
    Pediatric research, 2004, Volume: 56, Issue:4

    Topics: Age Factors; Animals; Animals, Newborn; Brain; Electron Transport Complex IV; Female; Glucose; L-Lac

2004
Angle closure glaucoma induced by ritodrine.
    Acta obstetricia et gynecologica Scandinavica, 2005, Volume: 84, Issue:5

    Topics: Adult; Back Pain; Diagnosis, Differential; Diagnostic Techniques, Ophthalmological; Female; Glaucoma

2005
Pilocarpine-induced seizure susceptibility in rats following prenatal methylazoxymethanol treatment.
    Biological & pharmaceutical bulletin, 2005, Volume: 28, Issue:8

    Topics: Animals; Disease Susceptibility; Female; Immunohistochemistry; Maternal Exposure; Methylazoxymethano

2005
Congenital brain dysplasias of different genesis can differently affect susceptibility to pilocarpine- or kainic acid-induced seizures in the rat.
    Epilepsy research, 2005, Volume: 67, Issue:3

    Topics: Animals; Behavior, Animal; Brain Diseases; Convulsants; Dose-Response Relationship, Drug; Electroenc

2005
Angle closure glaucoma induced by ritodrine.
    Acta obstetricia et gynecologica Scandinavica, 2006, Volume: 85, Issue:2

    Topics: Adult; Back Pain; Diagnosis, Differential; Diagnostic Techniques, Ophthalmological; Female; Glaucoma

2006
Interacting influences of pregnancy and corneal injury on rabbit lacrimal gland immunoarchitecture and function.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:4

    Topics: Animals; Blotting, Western; Cornea; Corneal Injuries; Electrophoresis, Polyacrylamide Gel; Epidermal

2006
Brains with different degrees of dysplasia show different patterns of neurodegenerative changes following pilocarpine-induced seizures. Histologic evidence of tissue damage correlated with MRI data.
    Neurological research, 2006, Volume: 28, Issue:4

    Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Brain; Female; Gestational Age; Magnetic R

2006
Enhanced mortality of rat pups following inductions of epileptic seizures after perinatal exposures to 5 nT, 7 Hz magnetic fields.
    Life sciences, 2007, Nov-10, Volume: 81, Issue:21-22

    Topics: Animals; Convulsants; Death, Sudden; Electromagnetic Fields; Female; Hippocampus; Lithium; Nitric Ox

2007
Drug-induced changes in fetal breathing activity and sleep state.
    Canadian journal of physiology and pharmacology, 1983, Volume: 61, Issue:4

    Topics: Animals; Caffeine; Doxapram; Female; Fetus; Indomethacin; Pilocarpine; Pregnancy; Respiration; Sheep

1983
Ultrastructural stereologic analysis of fetal rabbit type II alveolar epithelial cells following maternal pilocarpine treatment or fasting.
    The Anatomical record, 1982, Volume: 202, Issue:1

    Topics: Animals; Cell Count; Epithelial Cells; Epithelium; Fasting; Female; Fetal Organ Maturity; Fetus; Gly

1982
Supersensitization of the oral response to SKF 38393 in neonatal 6-hydroxydopamine-lesioned rats is eliminated by neonatal 5,7-dihydroxytryptamine treatment.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 5,7-Dihydroxytryptamine; Animals; Corpus

1994
Enhanced pilocarpine-induced oral activity responses in neonatal 6-OHDA treated rats.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Behavior, Ani

1993
Drug-induced ciliary body oedema: a new theory.
    Eye (London, England), 1996, Volume: 10 ( Pt 1)

    Topics: Acetazolamide; Adult; Asthma; Chlorthalidone; Ciliary Body; Diuretics; Edema; Epinephrine; Female; H

1996
Hormonal and gestational parameters in female rats submitted to the pilocarpine model of epilepsy.
    Epilepsy research, 1998, Volume: 32, Issue:1-2

    Topics: Animals; Epilepsy; Estradiol; Estrus; Female; Fertility; Follicle Stimulating Hormone; Humans; Lutei

1998
C-Fos, Jun D and HSP72 immunoreactivity, and neuronal injury following lithium-pilocarpine induced status epilepticus in immature and adult rats.
    Brain research. Molecular brain research, 1998, Dec-10, Volume: 63, Issue:1

    Topics: Age Factors; Animals; Brain Stem; Cerebral Cortex; Female; Heat-Shock Proteins; Hippocampus; HSP72 H

1998
Progressive metabolic changes underlying the chronic reorganization of brain circuits during the silent phase of the lithium-pilocarpine model of epilepsy in the immature and adult Rat.
    Experimental neurology, 2000, Volume: 162, Issue:1

    Topics: Age Factors; Animals; Behavior, Animal; Benzoxazines; Brain Stem; Carbon Radioisotopes; Cell Death;

2000
Protective effects of prenatal choline supplementation on seizure-induced memory impairment.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Animals; Behavior, Animal; Brain; Cell Count; Choline; Choline O-Acetyltransfe

2000
[Effect of several drugs and nonspecific substances on the uterine microflora of cows during the puerperal period and at the time of impregnation].
    Veterinarno-meditsinski nauki, 1978, Volume: 15, Issue:3

    Topics: Animals; Cattle; Chloramphenicol; Cholecalciferol; Citrates; Drug Interactions; Female; Hexestrol; P

1978
The maturation of the rabbit fetal lung following maternal administration of pilocarpine.
    The American journal of anatomy, 1979, Volume: 154, Issue:2

    Topics: Animals; Female; Fetus; Glycogen; Histocytochemistry; Inclusion Bodies; Liver Glycogen; Lung; Piloca

1979
Contact lenses.
    The New Zealand medical journal, 1978, Jun-14, Volume: 87, Issue:613

    Topics: Child; Contact Lenses; Contact Lenses, Hydrophilic; Counseling; Female; Glaucoma; Humans; Ophthalmic

1978
Reduced cell proliferation in fetal lung after maternal administration of pilocarpine: a scintillation autoradiographic study.
    The American journal of anatomy, 1979, Volume: 155, Issue:1

    Topics: Animals; Autoradiography; Cell Division; Female; Fetus; Lung; Maternal-Fetal Exchange; Pilocarpine;

1979
Role of autonomic nervous system controlling surface tension in fetal rabbit lungs.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1977, Volume: 43, Issue:6

    Topics: Animals; Autonomic Nervous System; Female; Isoxsuprine; Lung; Muscarine; Phenylephrine; Pilocarpine;

1977
Reduced surface tension in lungs of fetal rabbits injected with pilocarpine.
    Journal of applied physiology, 1976, Volume: 41, Issue:1

    Topics: Animals; Animals, Newborn; Depression, Chemical; Female; Fetus; Gestational Age; Lung; Pilocarpine;

1976
A new model for neonatal pulmonary hemorrhage research.
    Pediatric research, 1975, Volume: 9, Issue:4

    Topics: Animals; Animals, Newborn; Disease Models, Animal; Female; Hemorrhage; Humans; Infant, Newborn; Infa

1975
[Influence of the biological activity of substances on the puerperal period and fertility of cows].
    Veterinarno-meditsinski nauki, 1975, Volume: 12, Issue:9

    Topics: Animals; Cattle; Chloramphenicol; Citrates; Endometritis; Estrogens; Female; Fertility; Pilocarpine;

1975
Angle closure glaucoma precipitated by labour.
    Acta ophthalmologica, 1990, Volume: 68, Issue:2

    Topics: Acute Disease; Adult; Female; Glaucoma, Angle-Closure; Humans; Obstetric Labor Complications; Piloca

1990
Central muscarinic modulation of fetal blood pressure and heart rate.
    Journal of developmental physiology, 1990, Volume: 13, Issue:1

    Topics: Animals; Atropine; Atropine Derivatives; Blood Pressure; Female; Fetus; Heart Rate, Fetal; Pilocarpi

1990
Limitations of salivary and blood cortisol determinations in pigs.
    Veterinary research communications, 1989, Volume: 13, Issue:4

    Topics: Animals; Female; Hydrocortisone; Male; Pilocarpine; Pregnancy; Saliva; Specific Pathogen-Free Organi

1989
An embryonic Ca++ mobilizing muscarinic system in the chick embryo heart.
    Journal of developmental physiology, 1989, Volume: 12, Issue:2

    Topics: Animals; Benzofurans; Bethanechol; Bethanechol Compounds; Calcium; Carbachol; Chick Embryo; Chlortet

1989
A comparative study of salivary secretion by parotid and mandibular glands of anaesthetized Capra hircus: effect of pilocarpine.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1986, Volume: 85, Issue:2

    Topics: Animals; Female; Goats; Kinetics; Lactation; Organ Specificity; Parotid Gland; Pilocarpine; Pregnanc

1986
Cholinergic influences on sleep-wake patterns and breathing movements in the fetus.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:1

    Topics: Animals; Atropine; Atropine Derivatives; Dose-Response Relationship, Drug; Female; Fetus; Pilocarpin

1988
[Study on the postnatal neuro-behavioral development in rats treated prenatally with drugs acting on the autonomic nervous systems].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 85, Issue:2

    Topics: Animals; Atropine; Autonomic Agents; Central Nervous System Diseases; Chlorpromazine; Epinephrine; F

1985
The effect of pilocarpine and oxotremorine on oestrous behaviour in female rats after treatment with monoamine depletors or monoamine synthesis inhibitors.
    European journal of pharmacology, 1971, Volume: 15, Issue:1

    Topics: Amines; Animals; Castration; Estradiol; Estrus; Female; Fenclonine; Humans; Methyltyrosines; Pilocar

1971
5-Hydroxytryptamine and sexual behavior in the female rat.
    Advances in biochemical psychopharmacology, 1974, Volume: 11, Issue:0

    Topics: Amino Acids; Animals; Apomorphine; Castration; Circadian Rhythm; Electroshock; Estrus; Exploratory B

1974
[Pharmacological action of 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolinone hydrochloride (doxapram). 2. Peripheral action].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:2

    Topics: Animals; Autonomic Nervous System; Diaphragm; Doxapram; Female; Gastrointestinal Motility; Guinea Pi

1974
[Pharmacological studies on the vascular system of the human placenta].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:2

    Topics: Acetylcholine; Atropine; Blood Vessels; Caffeine; Carbon Dioxide; Ephedrine; Epinephrine; Ergotamine

1974
Experiments to stimulate ovarian function and uterine involution in cows after calving.
    Acta veterinaria Academiae Scientiarum Hungaricae, 1971, Volume: 21, Issue:2

    Topics: Animals; Cattle; Chloramphenicol; Citrates; Estradiol; Female; Fertilization; Muscle Contraction; Ov

1971
Urinary excretion of luteinizing hormone in women with glaucoma.
    Polish medical journal, 1970, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Age Factors; Female; Glaucoma; Humans; Luteinizing Hormone; Menopause; Ovary; Pil

1970
The effect of pilocarpine in combination with monoamine oxidase inhibitors, imipramine or desmethylimipramine on oestrous behaviour in female rats.
    Psychopharmacologia, 1970, Volume: 17, Issue:2

    Topics: Amines; Animals; Body Temperature; Castration; Central Nervous System; Desipramine; Drug Synergism;

1970
The effect of pilocarpine, oxotremorine and arecoline in combination with methyl-atropine or atropine on hormone activated oestrous behaviour in ovariectomized rats.
    Psychopharmacologia, 1967, Oct-06, Volume: 11, Issue:5

    Topics: Animals; Atropa belladonna; Atropine; Castration; Depression, Chemical; Drug Synergism; Estradiol; E

1967
Echothiophate iodide treatment of glaucoma in pregnancy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1968, Volume: 79, Issue:3

    Topics: Acetazolamide; Adult; Betamethasone; Bicarbonates; Cholinesterase Inhibitors; Cholinesterases; Echot

1968
Cystic fibrosis and pregnancy.
    JAMA, 1968, Jan-15, Volume: 203, Issue:3

    Topics: Adult; Cystic Fibrosis; Diagnosis, Differential; Female; Humans; Infant, Newborn; Iontophoresis; Pil

1968
Sweat electrolytes in mature and premature neonates after normal and pathological gestations and births.
    Polish medical science and history bulletin, 1968, Volume: 11, Issue:1

    Topics: Calcium; Cystic Fibrosis; Female; Humans; Infant, Newborn; Infant, Premature; Iontophoresis; Pilocar

1968