pilocarpine has been researched along with Obesity in 4 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seizures were induced in female Wistar albino rats at either 35 or 55 days of age with a single systemic injection of lithium (3 mEq/kg) and pilocarpine (30 mg/kg); the rats were then treated with the atypical neuroleptic acepromazine (25 mg/kg)." | 7.73 | Extreme obesity in female rats following prepuberal induction of lithium-pilocarpine seizures and a single injection of acepromazine. ( Persinger, MA; St-Pierre, LS, 2005) |
| "Chronically epileptic male adult rats in the pilocarpine model of temporal lobe epilepsy (TLE), exhibited gross expansion of abdominal fat mass and significant weight gain several months after induction of status epilepticus (SE) when compared to control rats." | 3.77 | Metabolic gene expression changes in the hippocampus of obese epileptic male rats in the pilocarpine model of temporal lobe epilepsy. ( Cox, CB; Ermolinsky, BS; Farrell, B; Garrido-Sanabria, ER; Nair, S; Pacheco, LF; Ruiz, N, 2011) |
| "Extreme obesity slowly develops in female rats over the months following seizures induced by a single systemic injection of lithium and pilocarpine if the resulting limbic seizures are treated with the atypical neuroleptic acepromazine (but not with ketamine)." | 3.75 | Insidious weight gain in prepubertal seized rats treated with an atypical neuroleptic: the role of food consumption, fluid consumption, and spontaneous ambulatory activity. ( Bubenik, GA; Parker, GH; Persinger, MA; St-Pierre, LS, 2009) |
| "Seizures were induced in female Wistar albino rats at either 35 or 55 days of age with a single systemic injection of lithium (3 mEq/kg) and pilocarpine (30 mg/kg); the rats were then treated with the atypical neuroleptic acepromazine (25 mg/kg)." | 3.73 | Extreme obesity in female rats following prepuberal induction of lithium-pilocarpine seizures and a single injection of acepromazine. ( Persinger, MA; St-Pierre, LS, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| St-Pierre, LS | 2 |
| Bubenik, GA | 1 |
| Parker, GH | 1 |
| Persinger, MA | 2 |
| Ruiz, N | 1 |
| Pacheco, LF | 1 |
| Farrell, B | 1 |
| Cox, CB | 1 |
| Ermolinsky, BS | 1 |
| Garrido-Sanabria, ER | 1 |
| Nair, S | 1 |
| Hart, CT | 1 |
| Haworth, S | 1 |
4 other studies available for pilocarpine and Obesity
| Article | Year |
|---|---|
Insidious weight gain in prepubertal seized rats treated with an atypical neuroleptic: the role of food consumption, fluid consumption, and spontaneous ambulatory activity.
Topics: Acepromazine; Analysis of Variance; Animals; Antipsychotic Agents; Body Weight; Disease Models, Anim | 2009 |
Metabolic gene expression changes in the hippocampus of obese epileptic male rats in the pilocarpine model of temporal lobe epilepsy.
Topics: Abdominal Fat; Analysis of Variance; Animals; Chronic Disease; Disease Models, Animal; Energy Metabo | 2011 |
Extreme obesity in female rats following prepuberal induction of lithium-pilocarpine seizures and a single injection of acepromazine.
Topics: Acepromazine; Animals; Body Weight; Chlorpromazine; Convulsants; Dopamine Antagonists; Female; Lithi | 2005 |
Bilateral common carotid occlusion with hypoxic ocular sequelae.
Topics: Adult; Aortography; Blood Pressure; Blood Proteins; Carotid Arteries; Carotid Artery Diseases; Eye D | 1971 |