pilocarpine has been researched along with Neurodegenerative Diseases in 3 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The reduction on seizure burden was associated with a limited reduction on the generation of SBDPs but was correlated with a reduction in astrocytosis, microglia activation and cell sprouting." | 1.46 | A calpain inhibitor ameliorates seizure burden in an experimental model of temporal lobe epilepsy. ( Carlsen, J; González, MI; Lam, PM, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, T | 1 |
| Ido, K | 1 |
| Osada, Y | 1 |
| Kotani, S | 1 |
| Tamaoka, A | 1 |
| Hanada, T | 1 |
| Reddy, DS | 1 |
| Kuruba, R | 1 |
| Lam, PM | 1 |
| Carlsen, J | 1 |
| González, MI | 1 |
1 review available for pilocarpine and Neurodegenerative Diseases
| Article | Year |
|---|---|
Experimental models of status epilepticus and neuronal injury for evaluation of therapeutic interventions.
Topics: Animals; Convulsants; Electric Stimulation Therapy; Flurothyl; Humans; Kainic Acid; Neurodegenerativ | 2013 |
2 other studies available for pilocarpine and Neurodegenerative Diseases
| Article | Year |
|---|---|
The neuroprotective effect of perampanel in lithium-pilocarpine rat seizure model.
Topics: Animals; Anticonvulsants; Antigens, Nuclear; Brain; Cell Death; Diazepam; Dose-Response Relationship | 2017 |
A calpain inhibitor ameliorates seizure burden in an experimental model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Calpain; Cerebral Cortex; Dipeptides; Disease Models, Animal; Dose-Respons | 2017 |