Page last updated: 2024-11-07

pilocarpine and Myopia

pilocarpine has been researched along with Myopia in 41 studies

Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.

Myopia: A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.

Research Excerpts

ExcerptRelevanceReference
"Pilocarpine 4% gel and pilocarpine 4% solution were compared in young normal subjects for their effects on induced myopia."9.06Reduced cyclic myopia with pilocarpine gel. ( Bruce, LA; Khalifa, MA; Mandell, AI, 1988)
"Eighteen glaucoma patients each received four pilocarpine regimens in random sequence: 1% and 4% eyedrops and 20mug/hr and 40mug/hr ocular therapeutic systems."9.04Visual effects of pilocarpine in glaucoma comparative study of administration by eyedrops or by ocular therapeutic systems. ( Brown, HS; Ferré, C; Fisher, M; Meltzer, G; Merrill, RC; Place, VA, 1976)
"Our research studies transitory myopia induced by Pilocarpine treatment in glaucoma patients."7.70[A myopia study of glaucoma patients following pilocarpine instillation]. ( Ban, C; Hanciu, D; Petroi, C; Pop, I, 2000)
"This special commentary reviews the treatment of presbyopia with a focus on the recently approved medication Vuity (pilocarpine 1."6.82Pilocarpine 1.25% and the changing landscape of presbyopia treatment. ( Ho, AC; Lee, JK; Meghpara, BB; Mian, SI; Rapuano, CJ, 2022)
"Tropicamide was used to induce mydriasis in a group of 12 volunteer student subjects aged 20-26 years (7 males, 5 female; mean 21."6.68Reversal of tropicamide mydriasis with single instillations of pilocarpine can induce substantial pseudo-myopia in young adults. ( Amer, AC; Gilmartin, B; Ingleby, S, 1995)
"Oral pilocarpine (Salagen) was prescribed, which improved salivation, lacrimation, and keratoconjunctivitis sicca."5.32Oral pilocarpine for the treatment of keratoconjunctivitis sicca with central corneal irregularity. ( Bhamra, J; Gohill, J; Wong, J, 2003)
"Pilocarpine 4% gel and pilocarpine 4% solution were compared in young normal subjects for their effects on induced myopia."5.06Reduced cyclic myopia with pilocarpine gel. ( Bruce, LA; Khalifa, MA; Mandell, AI, 1988)
"Eighteen glaucoma patients each received four pilocarpine regimens in random sequence: 1% and 4% eyedrops and 20mug/hr and 40mug/hr ocular therapeutic systems."5.04Visual effects of pilocarpine in glaucoma comparative study of administration by eyedrops or by ocular therapeutic systems. ( Brown, HS; Ferré, C; Fisher, M; Meltzer, G; Merrill, RC; Place, VA, 1976)
"Normal volunteers used 1, 2, and 4% pilocarpine eyedrops, three times daily, or ocular therapeutic systems placed in the conjunctival cul-de-sac to control intraocular pressure."5.04Comparative pharmacologic effects of pilocarpine administered to normal subjects by eyedrops or by ocular therapeutic systems. ( Fisher, M; Gordon, L; Herbst, S; Merrill, R; Place, VA, 1975)
"Eyes treated with pilocarpine developed approximately 6D myopia (p < 0."3.81Effects of muscarinic receptor modulators on ocular biometry of guinea pigs. ( Fang, F; Huang, F; Li, C; Liu, Y; Qu, J; Xie, R; Zhou, X; Zhu, Y, 2015)
"Our research studies transitory myopia induced by Pilocarpine treatment in glaucoma patients."3.70[A myopia study of glaucoma patients following pilocarpine instillation]. ( Ban, C; Hanciu, D; Petroi, C; Pop, I, 2000)
" In a second case report we describe, in a 61-year-old patient suffering from aspirin-sensitive asthma, recurrent ciliary body oedema with a marked spastic component which was triggered by the medications acetazolamide, dipivefrine and pilocarpine."3.69Drug-induced ciliary body oedema: a new theory. ( Krieg, PH; Schipper, I, 1996)
"Thirty-four patients with glaucoma were treated with the Ocusert pilocarpine system, a unique method of providing round-the-clock delivery of pilocarpine in the eye for seven-day periods."3.65The Ocusert pilocarpine system: advantages and disadvantages. ( Harbin, TS; Pollack, IP; Quigley, HA, 1976)
"This special commentary reviews the treatment of presbyopia with a focus on the recently approved medication Vuity (pilocarpine 1."2.82Pilocarpine 1.25% and the changing landscape of presbyopia treatment. ( Ho, AC; Lee, JK; Meghpara, BB; Mian, SI; Rapuano, CJ, 2022)
"Tropicamide was used to induce mydriasis in a group of 12 volunteer student subjects aged 20-26 years (7 males, 5 female; mean 21."2.68Reversal of tropicamide mydriasis with single instillations of pilocarpine can induce substantial pseudo-myopia in young adults. ( Amer, AC; Gilmartin, B; Ingleby, S, 1995)
"Oral pilocarpine (Salagen) was prescribed, which improved salivation, lacrimation, and keratoconjunctivitis sicca."1.32Oral pilocarpine for the treatment of keratoconjunctivitis sicca with central corneal irregularity. ( Bhamra, J; Gohill, J; Wong, J, 2003)
"Pilocarpine 2% was then instilled into the study eye and the field repeated at 30 and 120 minutes."1.27The effect of pilocarpine on the visual field in normals. ( Douglas, JP; Harvey, JS; Ivy, LM; McCluskey, DJ; O'Connor, PS; Story, K, 1986)
"Carbachol has the strongest side effects (maximal change of the anterior chamber 0."1.26Ultrasonographic study of the effect of different miotics on the eye components. ( François, J; Goes, F, 1977)
"Most of the patients with Adie's syndrome had a moderate accomodative paresis, but there was a strong tendency for the ciliary muscle to recover with time."1.26Ciliary muscle dysfunction in Adie's syndrome. ( Bell, RA; Thompson, HS, 1978)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199027 (65.85)18.7374
1990's5 (12.20)18.2507
2000's4 (9.76)29.6817
2010's2 (4.88)24.3611
2020's3 (7.32)2.80

Authors

AuthorsStudies
Meghpara, BB1
Lee, JK1
Rapuano, CJ1
Mian, SI1
Ho, AC1
Ozulken, K1
Yuksel, E1
Uzel, MM1
Tong, L1
Cui, D1
Zeng, J1
Fang, F1
Huang, F1
Xie, R1
Li, C1
Liu, Y1
Zhu, Y1
Qu, J1
Zhou, X1
Titiyal, JS1
Sharma, N1
Mannan, R1
Pruthi, A1
Vajpayee, RB1
Bhamra, J1
Wong, J1
Gohill, J1
Petternel, V1
Köppl, CM1
Dejaco-Ruhswurm, I1
Findl, O1
Skorpik, C1
Drexler, W1
Jones, RF1
McCracken, JS1
Bell, GR1
Gilmartin, B1
Amer, AC1
Ingleby, S1
Krieg, PH1
Schipper, I1
Charles, KC1
Pop, I1
Ban, C1
Hanciu, D1
Petroi, C1
François, J1
Goes, F1
Hillman, JS1
Walker, A1
Davies, EM1
Bell, RA1
Thompson, HS1
Heilmann, K1
Lienert, F1
Busse, H1
Kaufman, PL1
Brown, HS1
Meltzer, G1
Merrill, RC1
Fisher, M2
Ferré, C1
Place, VA2
Pollack, IP1
Quigley, HA1
Harbin, TS1
Mehta, HK1
Herbst, S1
Gordon, L1
Merrill, R1
Fechner, PU1
Teichmann, KD1
Weyrauch, W1
Bárány, EH1
Birkenfeld-Tierie, DA1
Brandt, HP1
Köhler, U1
Mandell, AI1
Bruce, LA1
Khalifa, MA1
McCluskey, DJ1
Douglas, JP1
O'Connor, PS1
Story, K1
Ivy, LM1
Harvey, JS1
Duffey, RJ1
Ferguson, JG1
Ourgaud, AG1
Tassy, A1
Rouanet, G1
Pouliquen, Y1
Heinrich, P1
Dausch, D1
Meythaler, H2
Braun, H1
Ruppert, W1
Aust, W1
Morlang, JL1
Tokoro, T1
Kanski, JJ1
Kerger, H1
Paul, W1
Wild, H1

Reviews

1 review available for pilocarpine and Myopia

ArticleYear
Pilocarpine 1.25% and the changing landscape of presbyopia treatment.
    Current opinion in ophthalmology, 2022, Jul-01, Volume: 33, Issue:4

    Topics: Humans; Myopia; Pilocarpine; Presbyopia; Vision, Ocular

2022

Trials

7 trials available for pilocarpine and Myopia

ArticleYear
Reversal of tropicamide mydriasis with single instillations of pilocarpine can induce substantial pseudo-myopia in young adults.
    Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 1995, Volume: 15, Issue:5

    Topics: Accommodation, Ocular; Adult; Double-Blind Method; Female; Humans; Male; Moxisylyte; Myopia; Pilocar

1995
Management of chronic glaucoma with pilocarpine Ocuserts.
    Transactions of the ophthalmological societies of the United Kingdom, 1977, Volume: 97, Issue:1

    Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Delayed-Action Preparations; Female; Glaucom

1977
[One year's experience with pilocarpin-ocusert in the therapy of glaucoma (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1975, Volume: 167, Issue:6

    Topics: Clinical Trials as Topic; Glaucoma; Humans; Myopia; Ophthalmic Solutions; Pharmaceutical Vehicles; P

1975
Visual effects of pilocarpine in glaucoma comparative study of administration by eyedrops or by ocular therapeutic systems.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1976, Volume: 94, Issue:10

    Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Female; Glaucoma; Humans; Intraocular Pre

1976
Comparative pharmacologic effects of pilocarpine administered to normal subjects by eyedrops or by ocular therapeutic systems.
    American journal of ophthalmology, 1975, Volume: 80, Issue:4

    Topics: Adult; Clinical Trials as Topic; Female; Humans; Intraocular Pressure; Male; Miotics; Myopia; Ophtha

1975
Reduced cyclic myopia with pilocarpine gel.
    Annals of ophthalmology, 1988, Volume: 20, Issue:4

    Topics: Adult; Female; Gels; Humans; Male; Myopia; Pilocarpine; Solutions; Time Factors

1988
[The myopic and miotic effect of pilocarpin and glaucostat].
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1971, Volume: 181, Issue:3

    Topics: Accommodation, Ocular; Adolescent; Adult; Child; Cocaine; Color; Eye; Humans; Hyperemia; Iris; Mioti

1971

Other Studies

33 other studies available for pilocarpine and Myopia

ArticleYear
Effect of topical pilocarpine on refractive surgery outcomes.
    International ophthalmology, 2020, Volume: 40, Issue:3

    Topics: Adolescent; Adult; Corneal Topography; Female; Humans; Keratomileusis, Laser In Situ; Lasers, Excime

2020
Effects of topical pilocarpine on ocular growth and refractive development in rabbits.
    European journal of ophthalmology, 2021, Volume: 31, Issue:4

    Topics: Animals; Cornea; Eye; Humans; Hyperopia; Myopia; Pilocarpine; Rabbits; Refraction, Ocular

2021
Effects of muscarinic receptor modulators on ocular biometry of guinea pigs.
    Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2015, Volume: 35, Issue:1

    Topics: Accommodation, Ocular; Administration, Topical; Analysis of Variance; Animals; Anterior Chamber; Cyc

2015
Outcomes of reenclavation of subluxated iris-fixated phakic intraocular lenses: comparison with primary surgery outcomes.
    Journal of cataract and refractive surgery, 2010, Volume: 36, Issue:4

    Topics: Adolescent; Adult; Cell Count; Corneal Endothelial Cell Loss; Endothelium, Corneal; Female; Follow-U

2010
Consultation section. Refractive surgical problem: 3 issues to be discussed: the clinical indications, the surgical procedure, the postoperative findings.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:1

    Topics: Adult; Brimonidine Tartrate; Contact Lenses; Corneal Topography; Diplopia; Drug Administration Sched

2003
Oral pilocarpine for the treatment of keratoconjunctivitis sicca with central corneal irregularity.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:11

    Topics: Administration, Oral; Adult; Corneal Topography; Female; Humans; Keratoconjunctivitis Sicca; Keratom

2003
Effect of accommodation and pupil size on the movement of a posterior chamber lens in the phakic eye.
    Ophthalmology, 2004, Volume: 111, Issue:2

    Topics: Accommodation, Ocular; Adult; Biometry; Ciliary Body; Female; Humans; Hyperopia; Interferometry; Iri

2004
THE SYNDROME OF MARCHESANI.
    The British journal of ophthalmology, 1961, Volume: 45, Issue:5

    Topics: Abnormalities, Multiple; Child; Child, Preschool; Ciliary Body; Consanguinity; Craniofacial Abnormal

1961
Silent night, blurry night.
    North Carolina medical journal, 1994, Volume: 55, Issue:12

    Topics: Adult; Emergencies; Eye Injuries; Humans; Male; Myopia; Pilocarpine; Visual Acuity

1994
High myopia trilogy.
    Journal of the American Optometric Association, 1995, Volume: 66, Issue:1

    Topics: Accommodation, Ocular; Animals; Humans; Intraocular Pressure; Macaca fascicularis; Myopia; Pilocarpi

1995
Drug-induced ciliary body oedema: a new theory.
    Eye (London, England), 1996, Volume: 10 ( Pt 1)

    Topics: Acetazolamide; Adult; Asthma; Chlorthalidone; Ciliary Body; Diuretics; Edema; Epinephrine; Female; H

1996
Screening for pupil size in prospective refractive surgery patients.
    Journal of cataract and refractive surgery, 1998, Volume: 24, Issue:3

    Topics: Corneal Transplantation; Humans; Laser Therapy; Myopia; Ophthalmic Solutions; Pilocarpine; Pupil; Vi

1998
[A myopia study of glaucoma patients following pilocarpine instillation].
    Oftalmologia (Bucharest, Romania : 1990), 2000, Volume: 52, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Female; Glaucoma, Open-Angle; Humans; Male; Middle

2000
Ultrasonographic study of the effect of different miotics on the eye components.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1977, Volume: 175, Issue:6

    Topics: Administration, Topical; Adult; Anterior Chamber; Carbachol; Epinephrine; Eye; Humans; Lens, Crystal

1977
Ciliary muscle dysfunction in Adie's syndrome.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1978, Volume: 96, Issue:4

    Topics: Accommodation, Ocular; Adie Syndrome; Adolescent; Adult; Astigmatism; Child; Ciliary Body; Female; H

1978
[Therapeutic systems: Ocusert. Progress in the treatment of chronic glaucoma by means of membrane-controlled drug administration].
    Fortschritte der Medizin, 1978, May-25, Volume: 96, Issue:20

    Topics: Administration, Topical; Alginates; Glaucoma; Humans; Intraocular Pressure; Membranes, Artificial; M

1978
Proceedings: Maintenance of maximal cholinergic response in primate ciliary muscle despite continuous cholinergic stimulation.
    Experimental eye research, 1975, Volume: 20, Issue:2

    Topics: Accommodation, Ocular; Animals; Ciliary Body; Echothiophate Iodide; Haplorhini; Myopia; Pilocarpine

1975
The Ocusert pilocarpine system: advantages and disadvantages.
    Southern medical journal, 1976, Volume: 69, Issue:10

    Topics: Drug Evaluation; Drug Implants; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; M

1976
Subconjunctival injection of pilocarpine.
    Transactions of the ophthalmological societies of the United Kingdom, 1976, Volume: 96, Issue:1

    Topics: Conjunctiva; Glaucoma; Humans; Injections; Intraocular Pressure; Lenses; Miotics; Myopia; Pilocarpin

1976
Accommodative effects of aceclidine in the treatment of glaucoma.
    American journal of ophthalmology, 1975, Volume: 79, Issue:1

    Topics: Accommodation, Ocular; Adult; Age Factors; Amides; Glaucoma; Humans; Intraocular Pressure; Middle Ag

1975
Subsensitivity to pilocarpine in primate ciliary muscle following topical anticholinesterase treatment.
    Investigative ophthalmology, 1975, Volume: 14, Issue:4

    Topics: Accommodation, Ocular; Animals; Atropine; Chlorocebus aethiops; Ciliary Body; Echothiophate Iodide;

1975
Severe myopia after pilocarpine in combination with phenylephrine eye drops.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1975, Volume: 171, Issue:1

    Topics: Adult; Drug Therapy, Combination; Glaucoma; Humans; Male; Myopia; Ophthalmic Solutions; Phenylephrin

1975
[Practical experiences with the pilocarpine-test for the early diagnosis of glaucoma (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1975, Volume: 166, Issue:4

    Topics: Age Factors; Aged; Glaucoma; Humans; Myopia; Pilocarpine; Time Factors

1975
The effect of pilocarpine on the visual field in normals.
    Ophthalmology, 1986, Volume: 93, Issue:6

    Topics: Adult; Humans; Middle Aged; Miotics; Myopia; Pilocarpine; Pupil; Visual Fields

1986
Interaction of dipivefrin and epinephrine with the pilocarpine ocular therapeutic system (Ocusert)
    Archives of ophthalmology (Chicago, Ill. : 1960), 1986, Volume: 104, Issue:8

    Topics: Adult; Delayed-Action Preparations; Drug Interactions; Drug Therapy, Combination; Epinephrine; Glauc

1986
[Carbaminoyl choline in the treatment of chronic open-angle glaucoma. Comparison with pilocarpin].
    Bulletin des societes d'ophtalmologie de France, 1973, Volume: 73, Issue:1

    Topics: Aqueous Humor; Benzalkonium Compounds; Carbachol; Drug Therapy, Combination; Glaucoma; Humans; Hyper

1973
[Hydrophilous contact lenses].
    Archives d'ophtalmologie et revue generale d'ophtalmologie, 1971, Volume: 31, Issue:4

    Topics: Astigmatism; Contact Lenses; Humans; Keratitis; Myopia; Pilocarpine

1971
[Miotics and retinal detachment (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1973, Volume: 163, Issue:4

    Topics: Adult; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Myopia; Pilocarpi

1973
[Tonographical examination on the effect of glaucadrine in the treatment of open-angle glaucoma (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1973, Volume: 163, Issue:6

    Topics: Aqueous Humor; Drug Combinations; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Myopia; Piloc

1973
[Pilocarpine induced myopia].
    Klinische Monatsblatter fur Augenheilkunde, 1970, Volume: 156, Issue:1

    Topics: Accommodation, Ocular; Adolescent; Adult; Age Factors; Child; Humans; Middle Aged; Myopia; Pilocarpi

1970
Experimental myopia in rabbits.
    Investigative ophthalmology, 1970, Volume: 9, Issue:12

    Topics: Animals; Atropine; Body Temperature; Disease Models, Animal; Epinephrine; Eye; Female; Intraocular P

1970
Miotics.
    The British journal of ophthalmology, 1968, Volume: 52, Issue:12

    Topics: Acetylcholine; Anterior Chamber; Carbachol; Cataract; Cholinesterase Inhibitors; Cysts; Echothiophat

1968
[On the myopic effect of Pilocarpin (1 per cent)-, Jestryl (Doryl) (1 per cent)- and Neoserin (Prostigmin) (3 per cent)-eyedrops].
    Acta ophthalmologica, 1969, Volume: 47, Issue:1

    Topics: Adolescent; Adult; Glaucoma; Humans; Middle Aged; Myopia; Neostigmine; Parasympathomimetics; Pilocar

1969