pilocarpine has been researched along with Mental Disorders in 7 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pilocarpine model of TLE has been widely used to study characteristics of human TLE, including behavioral comorbidities." | 5.42 | Evaluation of potential gender-related differences in behavioral and cognitive alterations following pilocarpine-induced status epilepticus in C57BL/6 mice. ( Fighera, MR; Funck, VR; Furian, AF; Grigoletto, J; Oliveira, CV; Oliveira, MS; Ribeiro, LR; Royes, LF, 2015) |
| "The pilocarpine model of TLE has been widely used to study characteristics of human TLE, including behavioral comorbidities." | 1.42 | Evaluation of potential gender-related differences in behavioral and cognitive alterations following pilocarpine-induced status epilepticus in C57BL/6 mice. ( Fighera, MR; Funck, VR; Furian, AF; Grigoletto, J; Oliveira, CV; Oliveira, MS; Ribeiro, LR; Royes, LF, 2015) |
| "The pilocarpine-treated rats (n =21) exhibited (a) a decreased exploratory activity in comparison with control rats (n = 20) in the open field (OP) test and (b) a slower extinction of exploratory behavior in repeated OP tests." | 1.42 | Impairment of exploratory behavior and spatial memory in adolescent rats in lithium-pilocarpine model of temporal lobe epilepsy. ( Frolova, EV; Kalemenev, SV; Kim, KKh; Lavrentyeva, VV; Lukomskaya, NY; Magazanik, LG; Sizov, VV; Zaitsev, AV; Zubareva, OE, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Di Liberto, V | 1 |
| van Dijk, RM | 1 |
| Brendel, M | 1 |
| Waldron, AM | 1 |
| Möller, C | 1 |
| Koska, I | 1 |
| Seiffert, I | 1 |
| Gualtieri, F | 1 |
| Gildehaus, FJ | 1 |
| von Ungern-Sternberg, B | 1 |
| Lindner, M | 1 |
| Ziegler, S | 1 |
| Palme, R | 1 |
| Hellweg, R | 1 |
| Gass, P | 1 |
| Bartenstein, P | 1 |
| Potschka, H | 1 |
| Oliveira, CV | 1 |
| Grigoletto, J | 1 |
| Funck, VR | 1 |
| Ribeiro, LR | 1 |
| Royes, LF | 1 |
| Fighera, MR | 1 |
| Furian, AF | 1 |
| Oliveira, MS | 1 |
| Kalemenev, SV | 1 |
| Zubareva, OE | 1 |
| Frolova, EV | 1 |
| Sizov, VV | 1 |
| Lavrentyeva, VV | 1 |
| Lukomskaya, NY | 1 |
| Kim, KKh | 1 |
| Zaitsev, AV | 1 |
| Magazanik, LG | 1 |
| BONETTI, U | 1 |
| STOLIAROV, GV | 1 |
| Masters, KJ | 1 |
| Loeber, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Xerostomy Treatment in Patients With Sjogren's Syndrome in Chile :A Double Blind Control Trial Comparing Orally Pilocarpine Drops and Artificial Saliva[NCT00438048] | Phase 4 | 76 participants (Actual) | Interventional | 2006-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for pilocarpine and Mental Disorders
| Article | Year |
|---|---|
Imaging correlates of behavioral impairments: An experimental PET study in the rat pilocarpine epilepsy model.
Topics: Animals; Disease Models, Animal; Epilepsy; Female; Interpersonal Relations; Mental Disorders; Piloca | 2018 |
Evaluation of potential gender-related differences in behavioral and cognitive alterations following pilocarpine-induced status epilepticus in C57BL/6 mice.
Topics: Age Factors; Analysis of Variance; Animals; Anticonvulsants; Cognition Disorders; Diazepam; Disease | 2015 |
Impairment of exploratory behavior and spatial memory in adolescent rats in lithium-pilocarpine model of temporal lobe epilepsy.
Topics: Adolescent; Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Exploratory Behavior; Humans; | 2015 |
[Neurological changes in psychotics explorated with potentiating substances (scopolamine, pilocarpine & somnifene)].
Topics: Barbiturates; Humans; Mental Disorders; Pilocarpine; Psychotic Disorders; Scopolamine | 1957 |
[ON ATROPINE PSYCHOSES].
Topics: Atropine; Humans; Mental Disorders; Morphine; Physostigmine; Pilocarpine; Psychoses, Substance-Induc | 1963 |
Pilocarpine treatment of xerostomia induced by psychoactive medications.
Topics: Adult; Aged; Humans; Mental Disorders; Middle Aged; Muscarinic Agonists; Pilocarpine; Psychotropic D | 2005 |
Care of psychiatric patients.
Topics: Cholinergic Antagonists; Humans; Mental Disorders; Parasympathomimetics; Pilocarpine; Xerostomia | 1998 |