pilocarpine has been researched along with Memory Disorders in 41 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Status epilepticus (SE) was induced via systemic injection of pilocarpine." | 7.91 | Over-expression of 5-HT6 Receptor and Activated Jab-1/p-c-Jun Play Important Roles in Pilocarpine-Induced Seizures and Learning-Memory Impairment. ( Huang, H; Huang, M; Lin, R; Lin, W; Liu, C; Ma, Y; Wen, Y, 2019) |
| "Rat pups age of 14 postnatal day (P14) were subjected to lithium-pilocarpine (Li-PC) model of status epilepticus (SE)." | 7.71 | Lithium-pilocarpine-induced status epilepticus in immature rats result in long-term deficits in spatial learning and hippocampal cell loss. ( Hsu, HY; Huang, LT; Lai, MC; Liou, CW; Tung, YR; Wang, TJ; Wu, CL, 2001) |
| "The effects of cathodal tDCS on convulsions and spatial memory after status epilepticus (SE) in immature animals were investigated." | 5.37 | Transcranial direct current stimulation decreases convulsions and spatial memory deficits following pilocarpine-induced status epilepticus in immature rats. ( Abe, T; Eshima, N; Fujiki, M; Kamida, T; Kobayashi, H; Kong, S, 2011) |
| " For this study, we used the same pilocarpine ramping-up dosing protocol and behavioral test battery than in a previous study in NMRI mice, thus allowing direct comparison between these two mouse strains." | 5.35 | Behavioral and cognitive alterations, spontaneous seizures, and neuropathology developing after a pilocarpine-induced status epilepticus in C57BL/6 mice. ( Bankstahl, M; Gröticke, I; Löscher, W; Müller, CJ, 2009) |
| " Status epilepticus (SE) was induced via systemic injection of pilocarpine." | 3.91 | Over-expression of 5-HT6 Receptor and Activated Jab-1/p-c-Jun Play Important Roles in Pilocarpine-Induced Seizures and Learning-Memory Impairment. ( Huang, H; Huang, M; Lin, R; Lin, W; Liu, C; Ma, Y; Wen, Y, 2019) |
| "Morris water maze test was used to evaluate learning and memory deficits in pilocarpine-induced chronic epilepsy rats 12 weeks after status epilepticus." | 3.88 | Decreased vesicular acetylcholine transporter related to memory deficits in epilepsy: A [ ( Cheng, DF; Ding, J; Shi, HC; Si, Z; Wang, X; Wu, XQ; Zhao, YN, 2018) |
| " In this study, we investigated the chronic effects of hypoxic preconditioning on spontaneous recurrent seizures (SRS), neuronal death, and spatial memory performance in rats subjected to pilocarpine (Pilo)-induced status epilepticus (SE)." | 3.83 | Decreased neuron loss and memory dysfunction in pilocarpine-treated rats pre-exposed to hypoxia. ( Balista, PA; Bassi, M; Do Val-da Silva, RA; Galvis-Alonso, OY; Glass, ML; Leite, JP; Peixoto-Santos, JE; Romcy-Pereira, RN; Scandiuzzi, RC, 2016) |
| " The recordings were performed in epileptic rats 24 h after an early behavioural spontaneous seizure between 5 and 21 days after pilocarpine-induced status epilepticus." | 3.74 | Synaptic plasticity of the CA3 commissural projection in epileptic rats: an in vivo electrophysiological study. ( Mello, LE; Queiroz, CM, 2007) |
| " The rats subjected to lithium-pilocarpine (Li/PC)-induced status epilepticus at P21 were grouped as the SE group." | 3.72 | Long-term effects of early-life malnutrition and status epilepticus: assessment by spatial navigation and CREB(Serine-133) phosphorylation. ( Hsieh, CS; Huang, LT; Lai, MC; Liou, CW; Wang, CA; Wang, CL; Yang, CH; Yang, SN, 2003) |
| "Rat pups age of 14 postnatal day (P14) were subjected to lithium-pilocarpine (Li-PC) model of status epilepticus (SE)." | 3.71 | Lithium-pilocarpine-induced status epilepticus in immature rats result in long-term deficits in spatial learning and hippocampal cell loss. ( Hsu, HY; Huang, LT; Lai, MC; Liou, CW; Tung, YR; Wang, TJ; Wu, CL, 2001) |
| ") also potentiates oxotremorine-induced tremors in mice, in a dose-dependent manner, and this effect was completely prevented by atropine." | 3.71 | Evidence for the involvement of the muscarinic cholinergic system in the central actions of pentoxifylline. ( Cunha, GM; Farias, PA; Viana, GS, 2002) |
| "Pilocarpine treatment significantly restored the scopolamine-induced impaired recognition memory and downregulated hippocampal IEGs expression and phosphorylation of ERK1/2 (extracellular signal-regulated kinase 1/2) and CREB (cAMP response element-binding protein)." | 1.72 | Muscarinic Acetylcholine Receptors-Mediated Activation of PKC Restores the Hippocampal Immediate Early Gene Expression and CREB Phosphorylation in Scopolamine-Induced Amnesic Mice. ( Barman, B; Kushwaha, A; Thakur, MK, 2022) |
| "Cognitive dysfunction is a major comorbidity of the epilepsies; however, treatments targeting seizure-associated cognitive dysfunction, particularly deficits in learning and memory are not available." | 1.46 | Scavenging of highly reactive gamma-ketoaldehydes attenuates cognitive dysfunction associated with epileptogenesis. ( Liang, LP; Patel, M; Pearson, JN; Roberts, LJ; Warren, E, 2017) |
| "The pilocarpine-treated rats (n =21) exhibited (a) a decreased exploratory activity in comparison with control rats (n = 20) in the open field (OP) test and (b) a slower extinction of exploratory behavior in repeated OP tests." | 1.42 | Impairment of exploratory behavior and spatial memory in adolescent rats in lithium-pilocarpine model of temporal lobe epilepsy. ( Frolova, EV; Kalemenev, SV; Kim, KKh; Lavrentyeva, VV; Lukomskaya, NY; Magazanik, LG; Sizov, VV; Zaitsev, AV; Zubareva, OE, 2015) |
| "The effects of cathodal tDCS on convulsions and spatial memory after status epilepticus (SE) in immature animals were investigated." | 1.37 | Transcranial direct current stimulation decreases convulsions and spatial memory deficits following pilocarpine-induced status epilepticus in immature rats. ( Abe, T; Eshima, N; Fujiki, M; Kamida, T; Kobayashi, H; Kong, S, 2011) |
| "Epilepsy affects 0." | 1.37 | Bone marrow mononuclear cells reduce seizure frequency and improve cognitive outcome in chronic epileptic rats. ( Cammarota, M; DaCosta, JC; Greggio, S; Machado, DC; Marinowic, DR; Venturin, GT; Zanirati, G, 2011) |
| " For this study, we used the same pilocarpine ramping-up dosing protocol and behavioral test battery than in a previous study in NMRI mice, thus allowing direct comparison between these two mouse strains." | 1.35 | Behavioral and cognitive alterations, spontaneous seizures, and neuropathology developing after a pilocarpine-induced status epilepticus in C57BL/6 mice. ( Bankstahl, M; Gröticke, I; Löscher, W; Müller, CJ, 2009) |
| "The treatment with pilocarpine improved in a specific manner these age-related deficits in 24 month-old rats without altering their motor performance." | 1.33 | Pilocarpine improves olfactory discrimination and social recognition memory deficits in 24 month-old rats. ( De-Mello, N; Prediger, RD; Takahashi, RN, 2006) |
| "Choline is an essential nutrient for rats and humans, and its availability during fetal development has long-lasting cognitive effects (Blusztajn, 1998)." | 1.31 | Protective effects of prenatal choline supplementation on seizure-induced memory impairment. ( Blusztajn, JK; Cermak, JM; Holmes, GL; Liu, Z; Neill, JC; Sarkisian, MR; Stafstrom, CE; Tandon, P; Yang, Y, 2000) |
| "Male adult rats that displayed limbic seizures between postnatal days 18 and 21 after a single s." | 1.29 | Deficits in working but not reference memory in adult rats in which limbic seizures had been induced before weaning: implications for early brain injuries. ( Kostakos, M; Peredery, O; Persinger, MA, 1993) |
| "2 mg/kg) of pilocarpine, a muscarinic agonist, showed a significant improvement of both types of memory deficit with bell shaped dose-response curves." | 1.28 | Differential effects of physostigmine and pilocarpine on the spatial memory deficits produced by two septo-hippocampal deafferentations in rats. ( Maeda, N; Matsuoka, N; Ohkubo, Y; Yamaguchi, I, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.44) | 18.7374 |
| 1990's | 2 (4.88) | 18.2507 |
| 2000's | 13 (31.71) | 29.6817 |
| 2010's | 20 (48.78) | 24.3611 |
| 2020's | 5 (12.20) | 2.80 |
| Authors | Studies |
|---|---|
| Mátyás, A | 1 |
| Borbély, E | 1 |
| Mihály, A | 1 |
| Barman, B | 1 |
| Kushwaha, A | 1 |
| Thakur, MK | 1 |
| Gelfuso, EA | 1 |
| Reis, SL | 1 |
| Pereira, AMS | 1 |
| Aguiar, DSR | 1 |
| Beleboni, RO | 1 |
| Jiang, Y | 2 |
| Liu, DF | 1 |
| Zhang, X | 2 |
| Liu, HG | 2 |
| Zhang, JG | 2 |
| Xing, J | 1 |
| Han, D | 1 |
| Xu, D | 1 |
| Li, X | 1 |
| Sun, L | 1 |
| Pacheco, ALD | 1 |
| de Melo, IS | 1 |
| de Souza, FMA | 1 |
| Nicácio, DCSP | 1 |
| Freitas-Santos, J | 1 |
| Oliveira Dos Santos, YM | 1 |
| Costa, MA | 1 |
| Cavalcante, CMB | 1 |
| Gomes Dos Santos Neto, J | 1 |
| Gitaí, DLG | 1 |
| Sabino-Silva, R | 1 |
| Torres de Miranda, C | 1 |
| Borbely, AU | 1 |
| Duzzioni, M | 1 |
| Shetty, AK | 1 |
| de Castro, OW | 1 |
| Han, CL | 1 |
| Wang, X | 2 |
| Meng, FG | 1 |
| Wu, XQ | 1 |
| Zhao, YN | 1 |
| Ding, J | 1 |
| Si, Z | 1 |
| Cheng, DF | 1 |
| Shi, HC | 1 |
| Ali, AE | 1 |
| Mahdy, HM | 1 |
| Elsherbiny, DM | 1 |
| Azab, SS | 1 |
| Liu, C | 1 |
| Wen, Y | 1 |
| Huang, H | 1 |
| Lin, W | 1 |
| Huang, M | 1 |
| Lin, R | 1 |
| Ma, Y | 1 |
| Sun, C | 1 |
| Fu, J | 1 |
| Qu, Z | 1 |
| Li, D | 1 |
| Si, P | 1 |
| Qiao, Q | 1 |
| Zhang, W | 1 |
| Xue, Y | 1 |
| Zhen, J | 1 |
| Wang, W | 1 |
| Smolensky, IV | 1 |
| Zubareva, OE | 2 |
| Kalemenev, SV | 2 |
| Lavrentyeva, VV | 2 |
| Dyomina, AV | 1 |
| Karepanov, AA | 1 |
| Zaitsev, AV | 2 |
| Brewster, AL | 1 |
| Lugo, JN | 1 |
| Patil, VV | 1 |
| Lee, WL | 1 |
| Qian, Y | 1 |
| Vanegas, F | 1 |
| Anderson, AE | 1 |
| Richard, GR | 2 |
| Titiz, A | 1 |
| Tyler, A | 1 |
| Holmes, GL | 5 |
| Scott, RC | 2 |
| Lenck-Santini, PP | 2 |
| Frolova, EV | 1 |
| Sizov, VV | 1 |
| Lukomskaya, NY | 1 |
| Kim, KKh | 1 |
| Magazanik, LG | 1 |
| Do Val-da Silva, RA | 1 |
| Peixoto-Santos, JE | 1 |
| Scandiuzzi, RC | 1 |
| Balista, PA | 1 |
| Bassi, M | 1 |
| Glass, ML | 1 |
| Romcy-Pereira, RN | 1 |
| Galvis-Alonso, OY | 1 |
| Leite, JP | 1 |
| Lima, IVA | 1 |
| Campos, AC | 1 |
| Bellozi, PMQ | 1 |
| Doria, JG | 1 |
| Ribeiro, FM | 1 |
| Moraes, MFD | 1 |
| de Oliveira, ACP | 1 |
| Pearson, JN | 1 |
| Warren, E | 1 |
| Liang, LP | 1 |
| Roberts, LJ | 1 |
| Patel, M | 1 |
| Chauvière, L | 1 |
| Rafrafi, N | 1 |
| Thinus-Blanc, C | 1 |
| Bartolomei, F | 1 |
| Esclapez, M | 1 |
| Bernard, C | 1 |
| Müller, CJ | 1 |
| Gröticke, I | 1 |
| Bankstahl, M | 1 |
| Löscher, W | 1 |
| Tomé, Ada R | 1 |
| Feitosa, CM | 1 |
| Freitas, RM | 1 |
| Kamida, T | 1 |
| Kong, S | 1 |
| Eshima, N | 1 |
| Abe, T | 1 |
| Fujiki, M | 1 |
| Kobayashi, H | 1 |
| Venturin, GT | 1 |
| Greggio, S | 1 |
| Marinowic, DR | 1 |
| Zanirati, G | 1 |
| Cammarota, M | 1 |
| Machado, DC | 1 |
| DaCosta, JC | 1 |
| Inostroza, M | 1 |
| Cid, E | 1 |
| Brotons-Mas, J | 1 |
| Gal, B | 1 |
| Aivar, P | 1 |
| Uzcategui, YG | 1 |
| Sandi, C | 1 |
| Menendez de la Prida, L | 1 |
| Tyler, AL | 1 |
| Mahoney, JM | 1 |
| Li, LY | 1 |
| Li, JL | 1 |
| Zhang, HM | 1 |
| Yang, WM | 1 |
| Wang, K | 1 |
| Fang, Y | 1 |
| Wang, Y | 1 |
| Córdova, SD | 1 |
| Loss, CM | 1 |
| de Oliveira, DL | 1 |
| Boukhezra, O | 1 |
| Riviello, P | 1 |
| Fu, DD | 1 |
| Lui, X | 1 |
| Zhao, Q | 2 |
| Akman, C | 1 |
| Huang, LT | 2 |
| Lai, MC | 2 |
| Wang, CL | 1 |
| Wang, CA | 1 |
| Yang, CH | 1 |
| Hsieh, CS | 1 |
| Liou, CW | 2 |
| Yang, SN | 1 |
| Detour, J | 1 |
| Schroeder, H | 1 |
| Desor, D | 1 |
| Nehlig, A | 1 |
| Prediger, RD | 1 |
| De-Mello, N | 1 |
| Takahashi, RN | 1 |
| Zhou, JL | 1 |
| Liu, ZW | 1 |
| Zhang, T | 1 |
| Yang, Z | 1 |
| Queiroz, CM | 1 |
| Mello, LE | 1 |
| Caine, ED | 1 |
| Kostakos, M | 1 |
| Persinger, MA | 1 |
| Peredery, O | 1 |
| Yang, Y | 1 |
| Liu, Z | 1 |
| Cermak, JM | 1 |
| Tandon, P | 1 |
| Sarkisian, MR | 1 |
| Stafstrom, CE | 1 |
| Neill, JC | 1 |
| Blusztajn, JK | 1 |
| Wu, CL | 1 |
| Wang, TJ | 1 |
| Tung, YR | 1 |
| Hsu, HY | 1 |
| Mishima, K | 1 |
| Egashira, N | 1 |
| Hirosawa, N | 1 |
| Fujii, M | 1 |
| Matsumoto, Y | 1 |
| Iwasaki, K | 1 |
| Fujiwara, M | 1 |
| Cunha, GM | 1 |
| Farias, PA | 1 |
| Viana, GS | 1 |
| Matsuoka, N | 1 |
| Maeda, N | 1 |
| Ohkubo, Y | 1 |
| Yamaguchi, I | 1 |
41 other studies available for pilocarpine and Memory Disorders
| Article | Year |
|---|---|
Hippocampal Sclerosis in Pilocarpine Epilepsy: Survival of Peptide-Containing Neurons and Learning and Memory Disturbances in the Adult NMRI Strain Mouse.
Topics: Aging; Animals; Calbindin 2; Cell Proliferation; Cell Survival; Densitometry; Epilepsy; Hippocampus; | 2021 |
Muscarinic Acetylcholine Receptors-Mediated Activation of PKC Restores the Hippocampal Immediate Early Gene Expression and CREB Phosphorylation in Scopolamine-Induced Amnesic Mice.
Topics: Amnesia; Animals; Cholinergic Agents; Cyclic AMP Response Element-Binding Protein; Genes, Immediate- | 2022 |
Neuroprotective effects and improvement of learning and memory elicited by erythravine and 11α-hydroxy-erythravine against the pilocarpine model of epilepsy.
Topics: Alkaloids; Animals; Convulsants; Epilepsy; Heterocyclic Compounds, 4 or More Rings; Hippocampus; Imm | 2020 |
Microstructure and functional connectivity-based evidence for memory-related regional impairments in the brains of pilocarpine-treated rats.
Topics: Amygdala; Animals; Brain; Diffusion Tensor Imaging; Entorhinal Cortex; Epilepsy, Temporal Lobe; Hipp | 2020 |
CREB Protects against Temporal Lobe Epilepsy Associated with Cognitive Impairment by Controlling Oxidative Neuronal Damage.
Topics: Animals; Apoptosis; Brain; Cognitive Dysfunction; Cyclic AMP Response Element-Binding Protein; Disea | 2019 |
Maternal crack cocaine use in rats leads to depressive- and anxiety-like behavior, memory impairment, and increased seizure susceptibility in the offspring.
Topics: Animals; Anxiety; Cocaine-Related Disorders; Crack Cocaine; Epilepsy; Female; Male; Memory Disorders | 2021 |
Abnormal hippocampal functional network and related memory impairment in pilocarpine-treated rats.
Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Exploratory Behavior; Hippocampus; Image P | 2018 |
Decreased vesicular acetylcholine transporter related to memory deficits in epilepsy: A [
Topics: Acholeplasmataceae; Animals; Brain; Chronic Disease; Disease Models, Animal; Epilepsy; Fluorodeoxygl | 2018 |
Rifampicin ameliorates lithium-pilocarpine-induced seizures, consequent hippocampal damage and memory deficit in rats: Impact on oxidative, inflammatory and apoptotic machineries.
Topics: Animals; Apoptosis; Hippocampus; Inflammation; Lithium Chloride; Male; Memory Disorders; Oxidative S | 2018 |
Over-expression of 5-HT6 Receptor and Activated Jab-1/p-c-Jun Play Important Roles in Pilocarpine-Induced Seizures and Learning-Memory Impairment.
Topics: Animals; COP9 Signalosome Complex; Intracellular Signaling Peptides and Proteins; Maze Learning; Mem | 2019 |
Chronic mild hypoxia promotes hippocampal neurogenesis involving Notch1 signaling in epileptic rats.
Topics: Animals; Cell Differentiation; Cell Proliferation; Cognition; Epilepsy; Hippocampus; Hypoxia; Male; | 2019 |
Impairments in cognitive functions and emotional and social behaviors in a rat lithium-pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Anxiety; Behavior, Animal; Cognition; Emotions; Epilepsy; Epilepsy, Temporal Lobe; Explorat | 2019 |
Rapamycin reverses status epilepticus-induced memory deficits and dendritic damage.
Topics: Animals; Dendrites; Dendritic Spines; Disease Models, Animal; Electroencephalography; Gliosis; Hippo | 2013 |
Speed modulation of hippocampal theta frequency correlates with spatial memory performance.
Topics: Animals; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Epilepsy, Temporal L | 2013 |
Impairment of exploratory behavior and spatial memory in adolescent rats in lithium-pilocarpine model of temporal lobe epilepsy.
Topics: Adolescent; Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Exploratory Behavior; Humans; | 2015 |
Decreased neuron loss and memory dysfunction in pilocarpine-treated rats pre-exposed to hypoxia.
Topics: Animals; Disease Models, Animal; Hippocampus; Ischemic Preconditioning; Male; Memory Disorders; Neur | 2016 |
Postictal alterations induced by intrahippocampal injection of pilocarpine in C57BL/6 mice.
Topics: Animals; Cell Death; Disease Models, Animal; Epilepsy, Temporal Lobe; Gliosis; Hippocampus; Male; Me | 2016 |
Scavenging of highly reactive gamma-ketoaldehydes attenuates cognitive dysfunction associated with epileptogenesis.
Topics: Aldehydes; Animals; Antioxidants; Cognitive Dysfunction; Disease Models, Animal; Epilepsy, Temporal | 2017 |
Early deficits in spatial memory and theta rhythm in experimental temporal lobe epilepsy.
Topics: Animals; Epilepsy, Temporal Lobe; Male; Memory; Memory Disorders; Pilocarpine; Rats; Rats, Wistar; S | 2009 |
Behavioral and cognitive alterations, spontaneous seizures, and neuropathology developing after a pilocarpine-induced status epilepticus in C57BL/6 mice.
Topics: Animals; Anxiety Disorders; Brain; Cognition Disorders; Convulsants; Disease Models, Animal; Epileps | 2009 |
Neuronal damage and memory deficits after seizures are reversed by ascorbic acid?
Topics: Animals; Antioxidants; Ascorbic Acid; Epilepsy; Hippocampus; Male; Memory Disorders; Neurons; Piloca | 2010 |
Transcranial direct current stimulation decreases convulsions and spatial memory deficits following pilocarpine-induced status epilepticus in immature rats.
Topics: Animals; Disease Models, Animal; Electric Stimulation Therapy; Hippocampus; Lithium Chloride; Male; | 2011 |
Bone marrow mononuclear cells reduce seizure frequency and improve cognitive outcome in chronic epileptic rats.
Topics: Animals; Bone Marrow Cells; Cell Transplantation; Chronic Disease; Cognition Disorders; Diazepam; Di | 2011 |
Hippocampal-dependent spatial memory in the water maze is preserved in an experimental model of temporal lobe epilepsy in rats.
Topics: Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Electrophysiology; Epilepsy, Temporal Lo | 2011 |
Functional network changes in hippocampal CA1 after status epilepticus predict spatial memory deficits in rats.
Topics: Animals; CA1 Region, Hippocampal; Disease Models, Animal; Electrodes, Implanted; Entropy; Image Proc | 2012 |
TGFβ1 treatment reduces hippocampal damage, spontaneous recurrent seizures, and learning memory deficits in pilocarpine-treated rats.
Topics: Administration, Intranasal; Animals; Apoptosis; Hippocampus; Lithium; Male; Maze Learning; Memory Di | 2013 |
Low-intensity physical training recovers object recognition memory impairment in rats after early-life induced Status epilepticus.
Topics: Animals; Behavior, Animal; Hippocampus; Male; Maze Learning; Memory Disorders; Physical Conditioning | 2013 |
Effect of the postictal state on visual-spatial memory in immature rats.
Topics: Animals; Animals, Newborn; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Convulsant | 2003 |
Long-term effects of early-life malnutrition and status epilepticus: assessment by spatial navigation and CREB(Serine-133) phosphorylation.
Topics: Animals; Animals, Newborn; Cell Death; Cyclic AMP Response Element-Binding Protein; Down-Regulation; | 2003 |
A 5-month period of epilepsy impairs spatial memory, decreases anxiety, but spares object recognition in the lithium-pilocarpine model in adult rats.
Topics: Animals; Anxiety; Behavior, Animal; Cell Count; Disease Models, Animal; Entorhinal Cortex; Epilepsy, | 2005 |
Pilocarpine improves olfactory discrimination and social recognition memory deficits in 24 month-old rats.
Topics: Aging; Animals; Discrimination, Psychological; Injections, Intraperitoneal; Male; Memory Disorders; | 2006 |
Effect of levetiracetam on visual-spatial memory following status epilepticus.
Topics: Animals; Anticonvulsants; Behavior, Animal; Cell Death; Disease Models, Animal; Electroencephalograp | 2007 |
Involvement of nitric oxide in spatial memory deficits in status epilepticus rats.
Topics: Animals; Glutathione Peroxidase; Guanidines; Hippocampus; Indazoles; Male; Malondialdehyde; Maze Lea | 2007 |
Synaptic plasticity of the CA3 commissural projection in epileptic rats: an in vivo electrophysiological study.
Topics: Action Potentials; Animals; Cell Death; Convulsants; Cortical Synchronization; Disease Models, Anima | 2007 |
Cholinomimetic treatment fails to improve memory disorders.
Topics: Adult; Female; Humans; Male; Memory Disorders; Middle Aged; Phosphatidylcholines; Pilocarpine | 1980 |
Deficits in working but not reference memory in adult rats in which limbic seizures had been induced before weaning: implications for early brain injuries.
Topics: Animals; Brain Injuries; Limbic System; Lithium; Male; Memory; Memory Disorders; Memory, Short-Term; | 1993 |
Protective effects of prenatal choline supplementation on seizure-induced memory impairment.
Topics: Acetylcholinesterase; Animals; Behavior, Animal; Brain; Cell Count; Choline; Choline O-Acetyltransfe | 2000 |
Lithium-pilocarpine-induced status epilepticus in immature rats result in long-term deficits in spatial learning and hippocampal cell loss.
Topics: Aging; Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Female; Hippocampus; Lithium; Male; | 2001 |
Characteristics of learning and memory impairment induced by delta9-tetrahydrocannabinol in rats.
Topics: Animals; Avoidance Learning; Discrimination Learning; Dronabinol; Hallucinogens; Injections, Intrave | 2001 |
Evidence for the involvement of the muscarinic cholinergic system in the central actions of pentoxifylline.
Topics: Acetylcholinesterase; Animals; Anxiety; Avoidance Learning; Hippocampus; Learning Disabilities; Male | 2002 |
Differential effects of physostigmine and pilocarpine on the spatial memory deficits produced by two septo-hippocampal deafferentations in rats.
Topics: Animals; Choline O-Acetyltransferase; Hippocampus; Male; Memory Disorders; Neurons, Afferent; Physos | 1991 |