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pilocarpine and Inadequate Sleep

pilocarpine has been researched along with Inadequate Sleep in 10 studies

Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.

Research Excerpts

ExcerptRelevanceReference
" Thus, the aim of the present study was to evaluate the effect of sleep deprivation in the expression of microRNA (miRNA) in the frontal cortex and heart tissues of adult male rats after 50days of saline (SAL) or pilocarpine-induced status epilepticus (PILO)."7.80The effects of sleep deprivation on microRNA expression in rats submitted to pilocarpine-induced status epilepticus. ( Andersen, ML; Cavalheiro, EA; Guindalini, C; Matos, G; Mazzotti, DR; Scorza, FA; Tufik, S, 2014)
" The present study evaluated the effects of sleep deprivation on locomotor activity and genetic damage in the brains of rats treated with saline or pilocarpine-induced status epilepticus (SE)."7.78Behavioral and genetic effects promoted by sleep deprivation in rats submitted to pilocarpine-induced status epilepticus. ( Alvarenga, TA; Andersen, ML; Cavalheiro, EA; Hirotsu, C; Le Sueur-Maluf, L; Matos, G; Noguti, J; Ribeiro, DA; Scorza, FA; Tufik, S, 2012)
"This study aimed to investigate the effect of a single injection of pilocarpine upon the phenomenon of cortical spreading depression (SD), in adult rats submitted to early malnutrition and/or to REM-sleep deprivation for 72h prior to the SD-recordings."7.72Malnutrition and REM-sleep deprivation modulate in rats the impairment of spreading depression by a single sub-convulsing dose of pilocarpine. ( De Oliveira Costat, LA; De Oliveira, JA; De Vasconcelos, CA; Guedes, RC, 2004)
" Thus, the aim of the present study was to evaluate the effect of sleep deprivation in the expression of microRNA (miRNA) in the frontal cortex and heart tissues of adult male rats after 50days of saline (SAL) or pilocarpine-induced status epilepticus (PILO)."3.80The effects of sleep deprivation on microRNA expression in rats submitted to pilocarpine-induced status epilepticus. ( Andersen, ML; Cavalheiro, EA; Guindalini, C; Matos, G; Mazzotti, DR; Scorza, FA; Tufik, S, 2014)
" The present study evaluated the effects of sleep deprivation on locomotor activity and genetic damage in the brains of rats treated with saline or pilocarpine-induced status epilepticus (SE)."3.78Behavioral and genetic effects promoted by sleep deprivation in rats submitted to pilocarpine-induced status epilepticus. ( Alvarenga, TA; Andersen, ML; Cavalheiro, EA; Hirotsu, C; Le Sueur-Maluf, L; Matos, G; Noguti, J; Ribeiro, DA; Scorza, FA; Tufik, S, 2012)
"This study aimed to investigate the effect of a single injection of pilocarpine upon the phenomenon of cortical spreading depression (SD), in adult rats submitted to early malnutrition and/or to REM-sleep deprivation for 72h prior to the SD-recordings."3.72Malnutrition and REM-sleep deprivation modulate in rats the impairment of spreading depression by a single sub-convulsing dose of pilocarpine. ( De Oliveira Costat, LA; De Oliveira, JA; De Vasconcelos, CA; Guedes, RC, 2004)
"Treatment with atropine prior to vehicle or ethanol produced a statistically significant decrease in PS, whereas pilocarpine had no effect on minutes of PS."1.35Participation of the cholinergic system in the ethanol-induced suppression of paradoxical sleep in rats. ( Andersen, ML; Papale, LA; Perry, JC; Tufik, S, 2008)
"Paradoxical sleep deprivation (PSD) induces changes in behaviors induced by dopaminergic and cholinergic agonists, including increased aggressive behavior and stereotypy, decreased number of yawns, and shedding of bloody tears in male rats."1.29Paradoxical sleep deprivation in female rats alters drug-induced behaviors. ( Hipólide, DC; Tufik, S, 1995)
" The results show a lowering of the dose-response curve obtained with apomorphine and pilocarpine, as well as a shift to the right in the curve obtained with physostigmine."1.27Does REM sleep deprivation induce subsensitivity of presynaptic dopamine or postsynaptic acetylcholine receptors in the rat brain? ( Braz, S; Neumann, BG; Silva-Filho, AR; Troncone, LR; Tufik, S, 1987)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's2 (20.00)18.2507
2000's4 (40.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirotsu, C2
Matos, G3
Tufik, S8
Andersen, ML4
Scorza, FA2
Mazzotti, DR1
Guindalini, C1
Cavalheiro, EA2
Guedes, RC2
de Vasconcelos, CA2
Papale, LA1
Perry, JC1
Ribeiro, DA1
Alvarenga, TA1
Le Sueur-Maluf, L1
Noguti, J1
De Oliveira, JA1
De Oliveira Costat, LA1
Hipólide, DC2
Lobo, LL2
de Medeiros, R1
Bueno, OF1
Oliveira, GM1
Morais, PR1
Melo, FH1
Troncone, LR1
Braz, S1
Silva-Filho, AR1
Neumann, BG1

Other Studies

10 other studies available for pilocarpine and Inadequate Sleep

ArticleYear
Changes in gene expression in the frontal cortex of rats with pilocarpine-induced status epilepticus after sleep deprivation.
    Epilepsy & behavior : E&B, 2013, Volume: 27, Issue:2

    Topics: Amidohydrolases; Analysis of Variance; Angiotensin-Converting Enzyme 2; Animals; Catalase; Disease M

2013
The effects of sleep deprivation on microRNA expression in rats submitted to pilocarpine-induced status epilepticus.
    Progress in neuro-psychopharmacology & biological psychiatry, 2014, Jun-03, Volume: 51

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Frontal Lobe; Gene Expression Regulation; Mal

2014
Sleep-deprivation enhances in adult rats the antagonistic effects of pilocarpine on cortical spreading depression: a dose-response study.
    Neuroscience letters, 2008, Sep-12, Volume: 442, Issue:2

    Topics: Animals; Cerebral Cortex; Cortical Spreading Depression; Dose-Response Relationship, Drug; Muscarini

2008
Participation of the cholinergic system in the ethanol-induced suppression of paradoxical sleep in rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2008, Volume: 41, Issue:9

    Topics: Animals; Atropine; Ethanol; Male; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; Rats; Ra

2008
Behavioral and genetic effects promoted by sleep deprivation in rats submitted to pilocarpine-induced status epilepticus.
    Neuroscience letters, 2012, May-02, Volume: 515, Issue:2

    Topics: Animals; DNA Damage; Hyperkinesis; Male; Motor Activity; Pilocarpine; Rats; Rats, Wistar; Sleep Depr

2012
Malnutrition and REM-sleep deprivation modulate in rats the impairment of spreading depression by a single sub-convulsing dose of pilocarpine.
    Nutritional neuroscience, 2004, Volume: 7, Issue:3

    Topics: Animals; Cortical Spreading Depression; Kinetics; Male; Malnutrition; Pilocarpine; Rats; Rats, Wista

2004
Paradoxical sleep deprivation in female rats alters drug-induced behaviors.
    Physiology & behavior, 1995, Volume: 57, Issue:6

    Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Body Temperature; Female; Pilocarpine; Rats; Rat

1995
Atropine increases pilocarpine-induced yawning behavior in paradoxical sleep deprived rats.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:3

    Topics: Animals; Atropine; Drug Synergism; Male; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; R

1995
Cholinergic modulation of inhibitory avoidance impairment induced by paradoxical sleep deprivation.
    Progress in neuro-psychopharmacology & biological psychiatry, 2000, Volume: 24, Issue:4

    Topics: Animals; Atropine; Avoidance Learning; Male; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpin

2000
Does REM sleep deprivation induce subsensitivity of presynaptic dopamine or postsynaptic acetylcholine receptors in the rat brain?
    European journal of pharmacology, 1987, Aug-11, Volume: 140, Issue:2

    Topics: Animals; Apomorphine; Brain Chemistry; Male; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Cho

1987