pilocarpine has been researched along with Hypoxia-Ischemia, Brain in 2 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We next used 2 models presenting with increased BBB permeability, hypoxia/reoxygenation and pilocarpine-induced status epilepticus, to assess the response of VWF(-/-) animals." | 3.79 | Endothelial Von Willebrand factor promotes blood-brain barrier flexibility and provides protection from hypoxia and seizures in mice. ( Brill, A; Cabral, JE; Cifuni, SM; De Meyer, SF; Suidan, GL; Voorhees, JR; Wagner, DD, 2013) |
| "To evaluate a potential insult in the cerebellum of pups exposed to maternal epileptic seizures during intrauterine life, female rats were subjected to pilocarpine-induced epilepsy." | 3.77 | Neuroglobin is up-regulated in the cerebellum of pups exposed to maternal epileptic seizures. ( Amado, D; Cavalheiro, EA; Cossa, AC; da Graça Naffah-Mazzacoratti, M; da Silva Fernandes, MJ; da Silva, IR; da Silva, JA; de Oliveira, EM; Higa, EM; Lima, DC; Perosa, SR, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suidan, GL | 1 |
| Brill, A | 1 |
| De Meyer, SF | 1 |
| Voorhees, JR | 1 |
| Cifuni, SM | 1 |
| Cabral, JE | 1 |
| Wagner, DD | 1 |
| Lima, DC | 1 |
| Cossa, AC | 1 |
| Perosa, SR | 1 |
| de Oliveira, EM | 1 |
| da Silva, JA | 1 |
| da Silva Fernandes, MJ | 1 |
| da Silva, IR | 1 |
| Higa, EM | 1 |
| da Graça Naffah-Mazzacoratti, M | 1 |
| Cavalheiro, EA | 1 |
| Amado, D | 1 |
2 other studies available for pilocarpine and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Endothelial Von Willebrand factor promotes blood-brain barrier flexibility and provides protection from hypoxia and seizures in mice.
Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Cells, Cultured; Claudin-5; Disease Models, An | 2013 |
Neuroglobin is up-regulated in the cerebellum of pups exposed to maternal epileptic seizures.
Topics: Animals; Animals, Newborn; Cerebellum; Epilepsy; Female; Glial Fibrillary Acidic Protein; Globins; H | 2011 |