Page last updated: 2024-11-07

pilocarpine and Hypothermia

pilocarpine has been researched along with Hypothermia in 8 studies

Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.

Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.

Research Excerpts

ExcerptRelevanceReference
" after they had been assigned to one of 8 groups in a 3-way analysis of variance design that involved (1) induction of limbic seizures by a systemic injection of lithium/pilocarpine, (2) physical restraint, and (3) administration of acepromazine."7.68Extreme hypothermia induced by a synergism of acute limbic seizures, physical restraint, and acepromazine: implications for survival following brain injury. ( Bureau, YR; Persinger, MA, 1993)
" The muscarinic agonist oxotremorine induced marked hypothermia in all the knockout mice, but the hypothermia was reduced in M2 and to a lesser extent in M3 knockout mice."3.72Role of specific muscarinic receptor subtypes in cholinergic parasympathomimetic responses, in vivo phosphoinositide hydrolysis, and pilocarpine-induced seizure activity. ( Bymaster, FP; Carter, PA; Felder, CC; Gomeza, J; Hamilton, SE; McKinzie, DL; Nathanson, NM; Wess, J; Yamada, M, 2003)
" The non-selective muscarinic agonists pilocarpine, oxotremorine, RS-86, S-aceclidine, but not the less active isomer R-aceclidine, also effectively stimulated PI hydrolysis in mice."3.70Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects. ( Bymaster, FP; Calligaro, DO; Carter, PA; DeLapp, N; Fink-Jensen, A; Jeppesen, L; Mitch, CH; Peters, SC; Rimvall, K; Sauerberg, P; Shannon, HE; Sheardown, MJ; Ward, JS; Whitesitt, CA; Zhang, W, 1998)
" after they had been assigned to one of 8 groups in a 3-way analysis of variance design that involved (1) induction of limbic seizures by a systemic injection of lithium/pilocarpine, (2) physical restraint, and (3) administration of acepromazine."3.68Extreme hypothermia induced by a synergism of acute limbic seizures, physical restraint, and acepromazine: implications for survival following brain injury. ( Bureau, YR; Persinger, MA, 1993)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bymaster, FP2
Carter, PA2
Yamada, M1
Gomeza, J1
Wess, J1
Hamilton, SE1
Nathanson, NM1
McKinzie, DL1
Felder, CC1
LOPEZCAMPOS, JL1
KRAYENBUEHL, HP1
KAKO, K1
LUETHY, E1
Bureau, YR1
Persinger, MA1
Peters, SC1
Zhang, W1
Ward, JS1
Mitch, CH1
Calligaro, DO1
Whitesitt, CA1
DeLapp, N1
Shannon, HE1
Rimvall, K1
Jeppesen, L1
Sheardown, MJ1
Fink-Jensen, A1
Sauerberg, P1
Staib, AH1
Schröder, M1
Dey, PK1
Mukherjee, A1
Zetler, G1

Other Studies

8 other studies available for pilocarpine and Hypothermia

ArticleYear
Role of specific muscarinic receptor subtypes in cholinergic parasympathomimetic responses, in vivo phosphoinositide hydrolysis, and pilocarpine-induced seizure activity.
    The European journal of neuroscience, 2003, Volume: 17, Issue:7

    Topics: Animals; Apomorphine; Body Temperature; Cerebral Cortex; Dopamine Agonists; Dose-Response Relationsh

2003
[INDUCTION OF EXPERIMENTAL NEPHRITIS ACCORDING TO THE METHOD OF BEREGI].
    Revista clinica espanola, 1964, May-31, Volume: 93

    Topics: Animals; Glomerulonephritis; Guinea Pigs; Hypothermia; Hypothermia, Induced; Immune Sera; Kidney Glo

1964
[RELATION BETWEEN MECHANICAL SYSTOLE DURATION AND FREQUENCY IN THE ANESTHETIZED RABBITS, WITH SPECIAL REFERENCE TO VARIOUS BRADYCARDIAS].
    Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere, 1964, Mar-12, Volume: 279

    Topics: Bradycardia; Electric Stimulation; Electrocardiography; Hypothermia; Hypothermia, Induced; Pharmacol

1964
Extreme hypothermia induced by a synergism of acute limbic seizures, physical restraint, and acepromazine: implications for survival following brain injury.
    Psychological reports, 1993, Volume: 72, Issue:1

    Topics: Acepromazine; Animals; Body Temperature Regulation; Brain Injuries; Chlorides; Hypothermia; Limbic S

1993
Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects.
    Brain research, 1998, Jun-08, Volume: 795, Issue:1-2

    Topics: Animals; Binding, Competitive; Brain Chemistry; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic

1998
[Participation of the cholinergic system in temperature regulation by the mouse].
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 192, Issue:1

    Topics: Acetylcholine; Alkaloids; Animals; Atropine; Benactyzine; Body Temperature; Body Temperature Regulat

1971
Responses of the circulatory system towards the vasoactive drugs in hypothermia under different anesthesia.
    Die Naturwissenschaften, 1967, Volume: 54, Issue:9

    Topics: Acetylcholine; Anesthesia; Animals; Blood Circulation; Cats; Epinephrine; Ergonovine; Heart; Histami

1967
Cataleptic state and hypothermia in mice, caused by central cholinergic stimulation and antagonized by anticholinergic and antidepressant drugs.
    International journal of neuropharmacology, 1968, Volume: 7, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Catalepsy; Desipramine; Hexamethonium Compo

1968