Page last updated: 2024-11-07

pilocarpine and Hyperhidrosis

pilocarpine has been researched along with Hyperhidrosis in 11 studies

Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.

Hyperhidrosis: Excessive sweating. In the localized type, the most frequent sites are the palms, soles, axillae, inguinal folds, and the perineal area. Its chief cause is thought to be emotional. Generalized hyperhidrosis may be induced by a hot, humid environment, by fever, or by vigorous exercise.

Research Excerpts

ExcerptRelevanceReference
"The effect of cisatracurium in a hyperhidrosis mice model induced by pilocarpine hydrochloride was monitored for sweat gland secretion, and ultrastructural sweat secretory granules in sweat glands were analyzed."4.12Antagonist of Chrna1 prevents the pathogenesis of primary focal hyperhidrosis. ( Kang, MQ; Li, X; Lin, JB; Lin, NL, 2022)
"Other complications included 2 Horner's syndromes--1 transient and 1 mild but permanent; 3 temporary intercostobrachial paraesthesias, 2 mild late recurrences of sweating and 2 compensatory increases in sweating."1.29Trans-axillary transpleural sympathectomy for Palmar hyperhidrosis in children--a 3 to 7 year follow-up of 9 cases. ( Cywes, S; Millar, AJ; Rode, H; Steiner, Z, 1994)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's2 (18.18)18.2507
2000's0 (0.00)29.6817
2010's3 (27.27)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Lin, JB1
Lin, NL1
Li, X1
Kang, MQ1
Amano, T1
Fujii, N1
Quan, YS1
Kenny, GP1
Kondo, N1
Yamashita, H1
Inoue, Y1
Pariser, DM1
Krishnaraja, J1
Tremblay, TM1
Rubison, RM1
Love, TW1
McGraw, BF1
Bosdotter Enroth, S1
Rystedt, A1
Covaciu, L1
Hymnelius, K1
Rystedt, E1
Nyberg, R1
Naver, H1
Swartling, C1
Taylor, J1
Woodcock, S1
Kavanagh, GM1
Weller, RB1
VIEIRA, CB1
MOCK, CJ1
JULIAN, OC1
Shih, CJ1
Lin, MT1
Millar, AJ1
Steiner, Z1
Rode, H1
Cywes, S1
Noppen, M1
Sevens, C1
Vincken, WG1
Jensen, O1

Trials

1 trial available for pilocarpine and Hyperhidrosis

ArticleYear
Randomized, Placebo- and Active-Controlled Crossover Study of the Safety and Efficacy of THVD-102, a Fixed-dose Combination of Oxybutynin and Pilocarpine, in Subjects With Primary Focal Hyperhidrosis.
    Journal of drugs in dermatology : JDD, 2017, Feb-01, Volume: 16, Issue:2

    Topics: Adult; Aged; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Humans; Hyperhidros

2017

Other Studies

10 other studies available for pilocarpine and Hyperhidrosis

ArticleYear
Antagonist of Chrna1 prevents the pathogenesis of primary focal hyperhidrosis.
    Annals of clinical and translational neurology, 2022, Volume: 9, Issue:6

    Topics: Animals; Brain-Derived Neurotrophic Factor; HEK293 Cells; Humans; Hyperhidrosis; Mice; Nicotinic Ant

2022
In vivo assessments of microneedle arrays and iontophoresis of pilocarpine in human palmar sweating.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 358

    Topics: Humans; Hyperhidrosis; Iontophoresis; Pilocarpine; Quality of Life; Sweat; Sweating

2023
Bilateral forearm intravenous regional anesthesia with prilocaine for botulinum toxin treatment of palmar hyperhidrosis.
    Journal of the American Academy of Dermatology, 2010, Volume: 63, Issue:3

    Topics: Adolescent; Adult; Anesthesia, Conduction; Anesthesia, Intravenous; Botulinum Toxins; Cohort Studies

2010
Hyperhidrotic and control subjects have similar sweating responses to pilocarpine administration.
    Journal of the American Academy of Dermatology, 2011, Volume: 64, Issue:3

    Topics: Adult; Female; Humans; Hyperhidrosis; Middle Aged; Muscarinic Agonists; Pilocarpine; Sweating

2011
[HYPERHIDROSIS INDUCED BY PILOCARPINE IN CHRONIC CHAGAS DISEASE].
    Hospital (Rio de Janeiro, Brazil), 1963, Volume: 64

    Topics: Chagas Disease; Esophagus; Heart Diseases; Humans; Hyperhidrosis; Pharmacology; Physiology; Pilocarp

1963
Bilateral dorsal sympathectomy for hyperhidrosis; comparison of response to adrenalin and pilocarpine of preganglionic and post-ganglionic sympathectomy in same patient.
    Angiology, 1951, Volume: 2, Issue:1

    Topics: Humans; Hyperhidrosis; Pilocarpine; Sweat Glands; Sympathectomy

1951
Effects of cholinomimetic drugs on sudomotor, metabolic, respiratory, vasomotor, and temperature response in palmar hyperhidrosis.
    Journal of neurosurgery, 1980, Volume: 53, Issue:5

    Topics: Adult; Basal Metabolism; Body Temperature; Ganglia, Sympathetic; Hand; Humans; Hyperhidrosis; Male;

1980
Trans-axillary transpleural sympathectomy for Palmar hyperhidrosis in children--a 3 to 7 year follow-up of 9 cases.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 1994, Volume: 4, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Female; Follow-Up Studies; Ganglia, Sympathetic; Hand; Horner S

1994
Effects of non-pharmacological sympathetic sudomotor denervation on sweating in humans with essential palmar hyperhidrosis.
    Clinical biochemistry, 1997, Volume: 30, Issue:2

    Topics: Adult; Electrolytes; Female; Forearm; Hand; Humans; Hyperhidrosis; Male; Middle Aged; Parasympathomi

1997
'Rusters'. The corrosive action of palmar sweat: I. Sodium chloride in sweat.
    Acta dermato-venereologica, 1979, Volume: 59, Issue:2

    Topics: Administration, Topical; Adolescent; Adult; Aluminum; Chlorides; Corrosion; Cystic Fibrosis; Dermato

1979