pilocarpine has been researched along with Hematologic Malignancies in 3 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pilocarpine hydrochloride has been reported to increase salivation and decrease oral mucositis in patients receiving head and neck radiotherapy, but there is only one report of its use in a cancer chemotherapy patient population." | 2.71 | Randomized controlled trial of pilocarpine hydrochloride for the moderation of oral mucositis during autologous blood stem cell transplantation. ( Brennan, MT; Fox, PC; Frenette, G; Kent, ML; Lockhart, PB; Norton, HJ; Packman, CH, 2005) |
| "Oral pilocarpine was able to reduce and normalize the elevated levels of Na, Mg, TP, Alb, EGF, IgG, and IgA salivary concentrations at both resting and stimulated conditions." | 1.32 | Sialometrical and sialochemical analysis of patients with chronic graft-versus-host disease--a prolonged study. ( Nagler, A; Nagler, RM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nagler, RM | 1 |
| Nagler, A | 1 |
| Lockhart, PB | 1 |
| Brennan, MT | 1 |
| Kent, ML | 1 |
| Packman, CH | 1 |
| Norton, HJ | 1 |
| Fox, PC | 1 |
| Frenette, G | 1 |
| Singhal, S | 1 |
| Powles, R | 1 |
| Treleaven, J | 1 |
| Rattenbury, H | 1 |
| Mehta, J | 1 |
2 trials available for pilocarpine and Hematologic Malignancies
| Article | Year |
|---|---|
Randomized controlled trial of pilocarpine hydrochloride for the moderation of oral mucositis during autologous blood stem cell transplantation.
Topics: Adult; Double-Blind Method; Female; Gingival Diseases; Hematologic Neoplasms; Humans; Male; Middle A | 2005 |
Pilocarpine hydrochloride for symptomatic relief of xerostomia due to chronic graft-versus-host disease or total-body irradiation after bone-marrow transplantation for hematologic malignancies.
Topics: Bone Marrow Transplantation; Chronic Disease; Graft vs Host Disease; Hematologic Neoplasms; Humans; | 1997 |
1 other study available for pilocarpine and Hematologic Malignancies
| Article | Year |
|---|---|
Sialometrical and sialochemical analysis of patients with chronic graft-versus-host disease--a prolonged study.
Topics: Adolescent; Adult; Albumins; Cations; Chronic Disease; Epidermal Growth Factor; Female; Follow-Up St | 2003 |