Page last updated: 2024-11-07

pilocarpine and Fibrosis

pilocarpine has been researched along with Fibrosis in 4 studies

Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.

Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.

Research Excerpts

ExcerptRelevanceReference
"Hederagenin (HE) plays a protective role by inhibiting cell proliferation and ameliorating fibrosis."8.12The protective effect of hederagenin on renal fibrosis by targeting muscarinic acetylcholine receptor. ( He, L; Yang, W, 2022)
"To measure the axial movement of an accommodating intraocular lens (IOL) induced by ciliary muscle contraction after application of pilocarpine."5.11Laserinterferometric assessment of pilocarpine-induced movement of an accommodating intraocular lens: a randomized trial. ( Buehl, W; Drexler, W; Findl, O; Koeppl, C; Kriechbaum, K; Menapace, R; Sacu, S; Wirtitsch, M, 2004)
"Hederagenin (HE) plays a protective role by inhibiting cell proliferation and ameliorating fibrosis."4.12The protective effect of hederagenin on renal fibrosis by targeting muscarinic acetylcholine receptor. ( He, L; Yang, W, 2022)
"The present study was designed to understand the molecular changes and cardiac parameters during different phases of epileptogenesis in lithium-pilocarpine (Li-pilo) rat model of epilepsy."3.91Spontaneous Recurrent Seizures Mediated Cardiac Dysfunction via mTOR Pathway Upregulation: A Putative Target for SUDEP Management. ( Mazumder, AG; Patial, V; Rana, AK; Sharma, S; Singh, D, 2019)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Yang, W1
He, L1
Sharma, S1
Mazumder, AG1
Rana, AK1
Patial, V1
Singh, D1
Findl, O1
Kriechbaum, K1
Menapace, R1
Koeppl, C1
Sacu, S1
Wirtitsch, M1
Buehl, W1
Drexler, W1
Baun, O1
Heegaard, S1
Kessing, SV1
Prause, JU1

Trials

1 trial available for pilocarpine and Fibrosis

ArticleYear
Laserinterferometric assessment of pilocarpine-induced movement of an accommodating intraocular lens: a randomized trial.
    Ophthalmology, 2004, Volume: 111, Issue:8

    Topics: Accommodation, Ocular; Aged; Aged, 80 and over; Ciliary Body; Female; Fibrosis; Humans; Interferomet

2004

Other Studies

3 other studies available for pilocarpine and Fibrosis

ArticleYear
The protective effect of hederagenin on renal fibrosis by targeting muscarinic acetylcholine receptor.
    Bioengineered, 2022, Volume: 13, Issue:4

    Topics: Cell Line; Fibrosis; Humans; Kidney; Kidney Diseases; Oleanolic Acid; Pilocarpine; Receptors, Muscar

2022
Spontaneous Recurrent Seizures Mediated Cardiac Dysfunction via mTOR Pathway Upregulation: A Putative Target for SUDEP Management.
    CNS & neurological disorders drug targets, 2019, Volume: 18, Issue:7

    Topics: Animals; Disease Models, Animal; Epilepsy; Fibrosis; Heart Diseases; Lithium Compounds; Male; Myocar

2019
The morphology of conjunctiva after long-term topical anti-glaucoma treatment. A quantitative analysis.
    Acta ophthalmologica Scandinavica, 1995, Volume: 73, Issue:3

    Topics: Administration, Topical; Adolescent; Adrenergic Agonists; Adrenergic beta-Antagonists; Adult; Aged;

1995