pilocarpine has been researched along with Epilepsia Partialis Continua in 2 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Epilepsia Partialis Continua: A variant of EPILEPSY characterized by continuous focal jerking of a body part over a period of hours, days, or even years without spreading to other body regions. Contractions may be aggravated by movement and are reduced, but not abolished during sleep. ELECTROENCEPHALOGRAPHY demonstrates epileptiform (spike and wave) discharges over the hemisphere opposite to the affected limb in most instances. The repetitive movements may originate from the CEREBRAL CORTEX or from subcortical structures (e.g., BRAIN STEM; BASAL GANGLIA). This condition is associated with Russian Spring and Summer encephalitis (see ENCEPHALITIS, TICK BORNE); Rasmussen syndrome (see ENCEPHALITIS); MULTIPLE SCLEROSIS; DIABETES MELLITUS; BRAIN NEOPLASMS; and CEREBROVASCULAR DISORDERS. (From Brain, 1996 April;119(pt2):393-407; Epilepsia 1993;34;Suppl 1:S29-S36; and Adams et al., Principles of Neurology, 6th ed, p319)
| Excerpt | Relevance | Reference |
|---|---|---|
| "An animal model of human complex partial status epilepticus induced by lithium chloride and pilocarpine administration was developed in our laboratory." | 3.70 | Nonconvulsive status epilepticus in rats: impaired responsiveness to exteroceptive stimuli. ( Druga, R; Hlinák, Z; Krsek, P; Mares, P; Mikulecká, A, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kapur, J | 1 |
| Lothman, EW | 1 |
| DeLorenzo, RJ | 1 |
| Mikulecká, A | 1 |
| Krsek, P | 1 |
| Hlinák, Z | 1 |
| Druga, R | 1 |
| Mares, P | 1 |
2 other studies available for pilocarpine and Epilepsia Partialis Continua
| Article | Year |
|---|---|
Loss of GABAA receptors during partial status epilepticus.
Topics: Animals; Electrophysiology; Epilepsia Partialis Continua; Kinetics; Lithium Chloride; Male; Muscimol | 1994 |
Nonconvulsive status epilepticus in rats: impaired responsiveness to exteroceptive stimuli.
Topics: Animals; Behavior, Animal; Brain; Disease Models, Animal; Electroencephalography; Epilepsia Partiali | 2000 |