pilocarpine has been researched along with Dystonia in 2 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The dopamine precursor levodopa (injected together with carbidopa) and the dopamine receptor agonist apomorphine increased the severity of dystonia in hamsters when administered prior to the age of maximum severity of dystonia." | 3.68 | Effects of pharmacological manipulation of dopaminergic and cholinergic neurotransmission in genetically dystonic hamsters. ( Fredow, G; Löscher, W, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Löscher, W | 1 |
| Fredow, G | 1 |
| Stewart, BR | 1 |
| Rupniak, NM | 1 |
| Jenner, P | 1 |
| Marsden, CD | 1 |
2 other studies available for pilocarpine and Dystonia
| Article | Year |
|---|---|
Effects of pharmacological manipulation of dopaminergic and cholinergic neurotransmission in genetically dystonic hamsters.
Topics: Acetylcholine; Animals; Apomorphine; Behavior, Animal; Carbidopa; Cricetinae; Dopamine; Drug Interac | 1992 |
Animal models of neuroleptic-induced acute dystonia.
Topics: Acute Disease; Animals; Antipsychotic Agents; Brain; Disease Models, Animal; Dystonia; Glutamate Dec | 1988 |