pilocarpine has been researched along with Drug Withdrawal Symptoms in 14 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the consequences of caffeine consumption on epileptic seizures, we used the pilocarpine and the kainate models of epilepsy." | 7.73 | Consequences of prolonged caffeine administration and its withdrawal on pilocarpine- and kainate-induced seizures in rats. ( Hoexter, MQ; Mello, LE; Rosa, PS; Tufik, S, 2005) |
| "Adult female rats that developed epilepsy following lithium-pilocarpine-induced status epilepticus (SE) were used." | 3.91 | Progesterone receptor activation regulates seizure susceptibility. ( Joshi, S; Kapur, J; Shiono, S; Williamson, J, 2019) |
| "To investigate the consequences of caffeine consumption on epileptic seizures, we used the pilocarpine and the kainate models of epilepsy." | 3.73 | Consequences of prolonged caffeine administration and its withdrawal on pilocarpine- and kainate-induced seizures in rats. ( Hoexter, MQ; Mello, LE; Rosa, PS; Tufik, S, 2005) |
| "Clozapine and haloperidol were tested for their ability to influence the acquisition of kindled seizures following electrical stimulation of the amygdala and ventral hippocampus." | 3.68 | Clozapine inhibits limbic system kindling: implications for antipsychotic action. ( Graham, SR; Kokkinidis, L, 1993) |
| "Haloperidol-induced c-fos was augmented in the striatum and pituitary, but reduced in the frontal cortex by chronic lithium treatment." | 1.30 | Basal and stimulated C-fos mRNA expression in the rat brain: effect of chronic dietary lithium. ( Mathé, AA; Miller, JC, 1997) |
| "Pretreatment with atropine sulphate (2." | 1.26 | Further studies on the role of cholinergic mechanisms in the development of increased naloxone potency in mice. ( Bentley, GA; Wong, CL, 1979) |
| "Pilocarpine was effective in reducing both 'wet-dog' like body shakes and aggression but it increased diarrhea and weight loss." | 1.26 | Effects of cholinergic agonists and antagonists on morphine-withdrawal syndrome. ( Gianutsos, G; Hynes, MD; Lal, H, 1976) |
| " Supersensitivity was observed, after daily oral dosing with hyoscine, in the increased salivation of mice in response to pilocarpine injected at least 66 h after withdrawing hyoscine." | 1.25 | Supersensitivity of salivation in response to pilocarpine after withdrawal of chronically administered hyoscine in the mouse. ( Parkes, MW; Parks, JC, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (57.14) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| da Silva Chaves, SN | 1 |
| Felício, GR | 1 |
| Costa, BPD | 1 |
| de Oliveira, WEA | 1 |
| Lima-Maximino, MG | 1 |
| Siqueira Silva, DH | 1 |
| Maximino, C | 1 |
| Shiono, S | 1 |
| Williamson, J | 1 |
| Kapur, J | 1 |
| Joshi, S | 1 |
| Hoexter, MQ | 1 |
| Rosa, PS | 1 |
| Tufik, S | 1 |
| Mello, LE | 1 |
| Persson, SA | 1 |
| Wahlström, G | 1 |
| Koga, Y | 1 |
| Inukai, T | 1 |
| Balabanova, S | 1 |
| Krupienski, M | 1 |
| Graham, SR | 1 |
| Kokkinidis, L | 1 |
| Miller, JC | 1 |
| Mathé, AA | 1 |
| Wong, CL | 1 |
| Bentley, GA | 1 |
| Glick, SD | 1 |
| Cox, RD | 1 |
| Hynes, MD | 1 |
| Gianutsos, G | 1 |
| Lal, H | 1 |
| Parkes, MW | 1 |
| Parks, JC | 1 |
| Jaffe, JH | 2 |
| Sharpless, SK | 2 |
| Friedman, MJ | 1 |
14 other studies available for pilocarpine and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Behavioral and biochemical effects of ethanol withdrawal in zebrafish.
Topics: Animals; Anxiety; Brain; Catalase; Darkness; Ethanol; Meta-Analysis as Topic; Models, Biological; Pi | 2018 |
Progesterone receptor activation regulates seizure susceptibility.
Topics: Animals; Female; Mifepristone; Norprogesterones; Pilocarpine; Progesterone; Rats; Rats, Sprague-Dawl | 2019 |
Consequences of prolonged caffeine administration and its withdrawal on pilocarpine- and kainate-induced seizures in rats.
Topics: Adenosine; Animals; Caffeine; Coffea; Disease Models, Animal; Dose-Response Relationship, Drug; Drin | 2005 |
Studies on interactions between striatal dopaminergic and cholinergic mechanisms in the early abstinence after chronic treatment with barbital in the rat.
Topics: Acetylcholine; Animals; Barbital; Barbiturates; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; H | 1984 |
Characterization of withdrawal syndrome of morphine-dependent rats prepared by intermittent infusion technique.
Topics: Animals; Body Weight; Humans; Infusions, Parenteral; Male; Morphine; Morphine Dependence; Motor Acti | 1981 |
[Detection of nicotine in eccrine sweat after stimulation of sweat glands during nicotine withdrawal].
Topics: Adolescent; Adult; Cotinine; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Metabolic C | 1995 |
Clozapine inhibits limbic system kindling: implications for antipsychotic action.
Topics: Acetylcholine; Amygdala; Animals; Antipsychotic Agents; Clozapine; Dopamine; Drug Interactions; Elec | 1993 |
Basal and stimulated C-fos mRNA expression in the rat brain: effect of chronic dietary lithium.
Topics: Amino Acid Isomerases; Animals; Blotting, Northern; Brain Chemistry; Carrier Proteins; Cholinergic A | 1997 |
Further studies on the role of cholinergic mechanisms in the development of increased naloxone potency in mice.
Topics: Abdominal Muscles; Animals; Atropine; Drug Synergism; Humans; Male; Mice; Morphine; Motor Activity; | 1979 |
Changes in sensitivity to operant effects of dopaminergic and cholinergic agents following morphine withdrawal in rats.
Topics: Animals; Apomorphine; Conditioning, Operant; Dopamine; Female; Haloperidol; Humans; Morphine; Piloca | 1977 |
Effects of cholinergic agonists and antagonists on morphine-withdrawal syndrome.
Topics: Animals; Atropine; Dexetimide; Humans; Male; Morphine Dependence; Pilocarpine; Rats; Scopolamine Der | 1976 |
Supersensitivity of salivation in response to pilocarpine after withdrawal of chronically administered hyoscine in the mouse.
Topics: Animals; Dose-Response Relationship, Drug; Humans; Mice; Pempidine; Pilocarpine; Salivation; Scopola | 1972 |
XVII. Pharmacological denervation supersensitivity in the central nervous system: a theory of physical dependence.
Topics: Animals; Autonomic Nervous System; Body Temperature; Denervation; Depression, Chemical; Drug Toleran | 1968 |
Central nervous system supersensitivity to pilocarpine after withdrawal of chronically administered scopolamine.
Topics: Animals; Body Temperature; Body Temperature Regulation; Central Nervous System; Drug Tolerance; Huma | 1969 |