pilocarpine has been researched along with Drug Refractory Epilepsy in 13 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Status epilepticus evoked by pilocarpine administeration was used to induce epilepsy in rats." | 3.81 | Dynamic Expression of MicroRNAs (183, 135a, 125b, 128, 30c and 27a) in the Rat Pilocarpine Model and Temporal Lobe Epilepsy Patients. ( Alsharafi, W; Xiao, B, 2015) |
| "In a rat model of status epilepticus (SE) induced by lithium and pilocarpine and refractory to midazolam, deep hypothermia (20 °C for 30 min) reduced EEG power over 50-fold, stopped SE within 12 min, and reduced EEG spikes by 87%." | 3.81 | Deep hypothermia for the treatment of refractory status epilepticus. ( Baldwin, R; Gezalian, M; Niquet, J; Wasterlain, CG, 2015) |
| "Epilepsy is a common neurological disorder." | 1.42 | Altered Expression of Intersectin1-L in Patients with Refractory Epilepsy and in Experimental Epileptic Rats. ( Li, M; Wang, S; Wang, X; Xu, X; Yang, X; Zhang, Y, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 11 (84.62) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Niquet, J | 2 |
| Lumley, L | 1 |
| Baldwin, R | 2 |
| Rossetti, F | 1 |
| Schultz, M | 1 |
| de Araujo Furtado, M | 1 |
| Suchomelova, L | 1 |
| Naylor, D | 1 |
| Franco-Estrada, I | 1 |
| Wasterlain, CG | 2 |
| Sanabria, V | 1 |
| Bittencourt, S | 1 |
| Perosa, SR | 1 |
| de la Rosa, T | 1 |
| da Graça Naffah-Mazzacoratti, M | 1 |
| Andersen, ML | 1 |
| Tufik, S | 1 |
| Cavalheiro, EA | 1 |
| Amado, D | 1 |
| Lu, D | 1 |
| Ji, Y | 1 |
| Sundaram, P | 1 |
| Traub, RD | 1 |
| Guan, Y | 1 |
| Zhou, J | 1 |
| Li, T | 1 |
| Zhe Sun, P | 1 |
| Luan, G | 1 |
| Okada, Y | 1 |
| Xu, T | 2 |
| Yu, X | 1 |
| Wang, T | 1 |
| Liu, Y | 1 |
| Liu, X | 2 |
| Ou, S | 2 |
| Chen, Y | 2 |
| Martinello, K | 1 |
| Sciaccaluga, M | 1 |
| Morace, R | 1 |
| Mascia, A | 1 |
| Arcella, A | 1 |
| Esposito, V | 1 |
| Fucile, S | 1 |
| Gao, F | 1 |
| Gao, Y | 1 |
| Meng, F | 1 |
| Yang, C | 1 |
| Fu, J | 1 |
| Li, Y | 1 |
| Saporito, MS | 1 |
| Gruner, JA | 1 |
| DiCamillo, A | 1 |
| Hinchliffe, R | 1 |
| Barker-Haliski, M | 1 |
| White, HS | 1 |
| Xu, K | 1 |
| Liu, F | 1 |
| Xu, W | 1 |
| Liu, J | 1 |
| Chen, S | 1 |
| Wu, G | 1 |
| Yang, X | 1 |
| Xu, X | 1 |
| Zhang, Y | 1 |
| Wang, S | 1 |
| Li, M | 1 |
| Wang, X | 2 |
| Alsharafi, W | 1 |
| Xiao, B | 1 |
| Gezalian, M | 1 |
| Huang, H | 1 |
| Li, R | 1 |
| Yuan, J | 1 |
| Zhou, X | 1 |
| Lai, Y | 1 |
| Hu, X | 1 |
| Chen, G | 1 |
| Zhu, B | 1 |
1 review available for pilocarpine and Drug Refractory Epilepsy
| Article | Year |
|---|---|
Early polytherapy for benzodiazepine-refractory status epilepticus.
Topics: Animals; Anticonvulsants; Benzodiazepines; Drug Administration Schedule; Drug Resistant Epilepsy; Dr | 2019 |
12 other studies available for pilocarpine and Drug Refractory Epilepsy
| Article | Year |
|---|---|
Hormonal and biochemical changes in female Proechimys guyannensis, an animal model of resistance to pilocarpine-induced status epilepticus.
Topics: Animals; Anticonvulsants; Blood Glucose; Disease Models, Animal; Drug Resistant Epilepsy; Female; Hi | 2020 |
Alkaline brain pH shift in rodent lithium-pilocarpine model of epilepsy with chronic seizures.
Topics: Animals; Brain; Brain Chemistry; Convulsants; Disease Models, Animal; Drug Resistant Epilepsy; Epile | 2021 |
The effect of CXCR2 inhibition on seizure activity in the pilocarpine epilepsy mouse model.
Topics: Adolescent; Adult; Animals; Anticonvulsants; Child; Child, Preschool; Disease Models, Animal; Drug R | 2017 |
Loss of constitutive functional γ-aminobutyric acid type A-B receptor crosstalk in layer 5 pyramidal neurons of human epileptic temporal cortex.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adolescent; Adult; Animals; Baclofen; Carbazoles; Cyclic AMP | 2018 |
The Sphingosine 1-Phosphate Analogue FTY720 Alleviates Seizure-induced Overexpression of P-Glycoprotein in Rat Hippocampus.
Topics: Anilides; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cycloox | 2018 |
Intravenously Administered Ganaxolone Blocks Diazepam-Resistant Lithium-Pilocarpine-Induced Status Epilepticus in Rats: Comparison with Allopregnanolone.
Topics: Administration, Intravenous; Anesthetics; Animals; Anticonvulsants; Diazepam; Drug Resistant Epileps | 2019 |
Transplanting GABAergic Neurons Differentiated from Neural Stem Cells into Hippocampus Inhibits Seizures and Epileptiform Discharges in Pilocarpine-Induced Temporal Lobe Epilepsy Model.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Drug Resistant Epilepsy; Electroencephalography; | 2019 |
Altered Expression of Intersectin1-L in Patients with Refractory Epilepsy and in Experimental Epileptic Rats.
Topics: Adaptor Proteins, Vesicular Transport; Adolescent; Adult; Animals; Brain; Disease Models, Animal; Dr | 2015 |
Dynamic Expression of MicroRNAs (183, 135a, 125b, 128, 30c and 27a) in the Rat Pilocarpine Model and Temporal Lobe Epilepsy Patients.
Topics: Adult; Aged; Animals; Child; Disease Models, Animal; Drug Resistant Epilepsy; Epilepsy, Temporal Lob | 2015 |
Deep hypothermia for the treatment of refractory status epilepticus.
Topics: Animals; Convulsants; Drug Resistant Epilepsy; Electroencephalography; Hypothermia, Induced; Lithium | 2015 |
Up-regulated ephrinB3/EphB3 expression in intractable temporal lobe epilepsy patients and pilocarpine induced experimental epilepsy rat model.
Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Disease Models, Animal; Drug Resistant Epilepsy | 2016 |
Down-regulation of adenylate kinase 5 in temporal lobe epilepsy patients and rat model.
Topics: Adenylate Kinase; Adolescent; Adult; Animals; Brain Injuries, Traumatic; Carrier Proteins; Child; Di | 2016 |