pilocarpine has been researched along with Disease Exacerbation in 37 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Initial seizures observed in young rats during the 60 min after administration of pilocarpine (Pilo) were delayed and attenuated by pretreatment with a non-convulsive dose of methionine sulfoximine (MSO)." | 8.02 | Inhibition of Glutamate Release, but Not of Glutamine Recycling to Glutamate, Is Involved in Delaying the Onset of Initial Lithium-Pilocarpine-Induced Seizures in Young Rats by a Non-Convulsive MSO Dose. ( Albrecht, J; Aldana, BI; Belfiori-Carrasco, LF; Czarnecka, AM; Obara-Michlewska, M; Pawlik, MJ; Popek, MP, 2021) |
| " To determine if a single event of status epilepticus and its latent consequences can affect motor map expression, we assessed forelimb motor maps in rats using the pilocarpine model of temporal lobe epilepsy." | 7.75 | Motor map expansion in the pilocarpine model of temporal lobe epilepsy is dependent on seizure severity and rat strain. ( Flynn, C; Ozen, LJ; Teskey, GC; Vuong, J; Young, NA, 2009) |
| " In the present study in mGluR5 wild-type (mGluR5+/+) mice, we showed induced PKCbeta2 or PKCgamma expression at the border between the stratum oriens and alveus (O/A border) at 2h during pilocarpine induced status epilepticus (SE), and in the stratum pyramidale in CA1 area at 1 day after pilocarpine induced SE; at 1 day, induced expression of PLCbeta4 in the stratum pyramidale of CA1 area was observed." | 7.74 | mGluR5-PLCbeta4-PKCbeta2/PKCgamma pathways in hippocampal CA1 pyramidal neurons in pilocarpine model of status epilepticus in mGluR5+/+ mice. ( Liu, JX; Liu, Y; Tang, FR; Tang, YC, 2008) |
| "Recently we reported that astroglial loss and subsequent gliogenesis in the dentate gyrus play a role in epileptogenesis following pilocarpine-induced status epilepticus (SE)." | 7.74 | Spatiotemporal characteristics of astroglial death in the rat hippocampo-entorhinal complex following pilocarpine-induced status epilepticus. ( Choi, KC; Choi, SY; Kang, TC; Kim, DS; Kim, DW; Kim, JE; Kwak, SE; Kwon, OS, 2008) |
| "The aim of the study was to determine whether (1) number of febrile convulsions is a predictor of development of temporal lobe epilepsy, (2) the susceptibility of rats to pilocarpine-induced seizures is increased due to febrile convulsions and (3) nitric oxide is a mediator in the pathogenesis of febrile convulsions." | 7.71 | Do recurrent febrile convulsions decrease the threshold for pilocarpine-induced seizures? Effects of nitric oxide. ( Gulec, G; Noyan, B, 2001) |
| "The course of untreated epilepsy is not well established." | 5.30 | The course of untreated seizures in the pilocarpine model of epilepsy. ( Arida, RM; Cavalheiro, EA; Peres, CA; Scorza, FA, 1999) |
| "Initial seizures observed in young rats during the 60 min after administration of pilocarpine (Pilo) were delayed and attenuated by pretreatment with a non-convulsive dose of methionine sulfoximine (MSO)." | 4.02 | Inhibition of Glutamate Release, but Not of Glutamine Recycling to Glutamate, Is Involved in Delaying the Onset of Initial Lithium-Pilocarpine-Induced Seizures in Young Rats by a Non-Convulsive MSO Dose. ( Albrecht, J; Aldana, BI; Belfiori-Carrasco, LF; Czarnecka, AM; Obara-Michlewska, M; Pawlik, MJ; Popek, MP, 2021) |
| " In epileptic rats analyzed up to approximately two weeks after pilocarpine-induced status epilepticus (SE), these patterns are associated with specific high-frequency oscillation (HFO) content: ripples (80-200Hz) or fast-ripples (250-500Hz) predominate in LVF or HYP seizures, respectively." | 3.85 | Time-dependent evolution of seizures in a model of mesial temporal lobe epilepsy. ( Avoli, M; Behr, C; Lévesque, M; Stroh, T, 2017) |
| "We aimed to discuss the mechanism of occurrence and progression of epilepsy through analyzing the expression changes of UCA1 and NF-Kb in temporal hippocampus and UCA1 in peripheral blood in rats with epilepsy induced by lithium chloride-pilocarpine." | 3.85 | Dynamic regulation effect of long non-coding RNA-UCA1 on NF-kB in hippocampus of epilepsy rats. ( Wang, HK; Wang, J; Wang, K; Yan, H, 2017) |
| " Epileptogenesis was initiated using the pilocarpine status epilepticus model in male and female mice." | 3.85 | Ablation of peri-insult generated granule cells after epilepsy onset halts disease progression. ( Danzer, SC; Hosford, BE; Liska, JP; Rowley, S, 2017) |
| " Epileptic rats that developed spontaneous recurrent seizures after a pilocarpine-induced status epilepticus were treated with a KD or control diet (CD)." | 3.81 | Ketogenic diet prevents epileptogenesis and disease progression in adult mice and rats. ( Akula, KK; Boison, D; Coffman, SQ; Lusardi, TA; Masino, SA; Ruskin, DN, 2015) |
| "We have previously reported that an episode of pentylenetetrazole (PTZ)-induced status epilepticus (SE) in immature rats induces a long-term increase in cholinergic excitation assessed in the adult brain in vitro." | 3.80 | A single episode of juvenile status epilepticus reduces the threshold to adult seizures in a stimulus-specific way. ( Kouis, P; Mikroulis, A; Psarropoulou, C, 2014) |
| " Using pimonidazole, which probes hypoxic insults, we found that by increasing the duration of pilocarpine-induced status epilepticus (SE) from 30 to 120 min, counts of pimonidazole-immunoreactive neurons also increased (P < 0." | 3.79 | Hypoxia markers are expressed in interneurons exposed to recurrent seizures. ( Biagini, G; Gualtieri, F; Longo, D; Marinelli, C; Meletti, S; Nichelli, PF; Pugnaghi, M, 2013) |
| "The present study examined whether status epilepticus (SE) induced by LiCl-pilocarpine in immature rats (postnatal day [P]12) interferes with normal development; leads to progressive epileptogenesis, or cognitive decline and to pathology similar to that seen in human temporal lobe epilepsy." | 3.79 | Are morphologic and functional consequences of status epilepticus in infant rats progressive? ( Kubová, H; Mareš, P, 2013) |
| " To determine if a single event of status epilepticus and its latent consequences can affect motor map expression, we assessed forelimb motor maps in rats using the pilocarpine model of temporal lobe epilepsy." | 3.75 | Motor map expansion in the pilocarpine model of temporal lobe epilepsy is dependent on seizure severity and rat strain. ( Flynn, C; Ozen, LJ; Teskey, GC; Vuong, J; Young, NA, 2009) |
| " In the present study in mGluR5 wild-type (mGluR5+/+) mice, we showed induced PKCbeta2 or PKCgamma expression at the border between the stratum oriens and alveus (O/A border) at 2h during pilocarpine induced status epilepticus (SE), and in the stratum pyramidale in CA1 area at 1 day after pilocarpine induced SE; at 1 day, induced expression of PLCbeta4 in the stratum pyramidale of CA1 area was observed." | 3.74 | mGluR5-PLCbeta4-PKCbeta2/PKCgamma pathways in hippocampal CA1 pyramidal neurons in pilocarpine model of status epilepticus in mGluR5+/+ mice. ( Liu, JX; Liu, Y; Tang, FR; Tang, YC, 2008) |
| "Recently we reported that astroglial loss and subsequent gliogenesis in the dentate gyrus play a role in epileptogenesis following pilocarpine-induced status epilepticus (SE)." | 3.74 | Spatiotemporal characteristics of astroglial death in the rat hippocampo-entorhinal complex following pilocarpine-induced status epilepticus. ( Choi, KC; Choi, SY; Kang, TC; Kim, DS; Kim, DW; Kim, JE; Kwak, SE; Kwon, OS, 2008) |
| "The rodent pilocarpine model of epilepsy exhibits hippocampal sclerosis and spontaneous seizures and thus resembles human temporal lobe epilepsy." | 3.72 | Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model. ( Almonte, AG; Borges, K; Dingledine, R; Gearing, M; McDermott, DL; Smith, AB; Wainer, BH, 2003) |
| "The aim of the study was to determine whether (1) number of febrile convulsions is a predictor of development of temporal lobe epilepsy, (2) the susceptibility of rats to pilocarpine-induced seizures is increased due to febrile convulsions and (3) nitric oxide is a mediator in the pathogenesis of febrile convulsions." | 3.71 | Do recurrent febrile convulsions decrease the threshold for pilocarpine-induced seizures? Effects of nitric oxide. ( Gulec, G; Noyan, B, 2001) |
| "Dry mouth (xerostomia) is one of the commonest symptoms in cancer patients and can adversely affect quality of life." | 2.52 | Systematic literature review: xerostomia in advanced cancer patients. ( Adkinson, L; Daniel, S; Fleming, M; Hanchanale, S; Oxberry, SG, 2015) |
| "We undermitted the patient the dental treatment of Sjogren's syndrome." | 2.47 | Scleroderma and CREST syndrome: a case report in dentistry. ( Baldoni, M; Bussolati, A; Lauritano, D; Leonida, A, 2011) |
| "Drug therapy for glaucoma is based on lowering of intraocular pressure regardless of the pressure level, at which the disease has been diagnosed." | 2.45 | [Drug therapy for glaucoma]. ( Määttä, M; Puska, P, 2009) |
| "Dorzolamide was on the third place, but it generated the biggest part of total costs." | 1.31 | [Analysis of glaucoma therapy costs in Poland. I--population of the Mazovian District]. ( Anielska, E; Czechowicz-Janicka, K; Dyczkowska, A; Orlewska, E; Tobota, Z, 2000) |
| "Spontaneous behavioral seizures were observed in BDNF-infused rats (8/32; 25%) but not in controls (0/20; 0%)." | 1.31 | Spontaneous limbic seizures after intrahippocampal infusion of brain-derived neurotrophic factor. ( Croll, SD; Goodman, JH; Scharfman, HE; Sollas, AL, 2002) |
| "The course of untreated epilepsy is not well established." | 1.30 | The course of untreated seizures in the pilocarpine model of epilepsy. ( Arida, RM; Cavalheiro, EA; Peres, CA; Scorza, FA, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.70) | 18.2507 |
| 2000's | 16 (43.24) | 29.6817 |
| 2010's | 16 (43.24) | 24.3611 |
| 2020's | 4 (10.81) | 2.80 |
| Authors | Studies |
|---|---|
| Pawlik, MJ | 1 |
| Aldana, BI | 1 |
| Belfiori-Carrasco, LF | 1 |
| Obara-Michlewska, M | 1 |
| Popek, MP | 1 |
| Czarnecka, AM | 1 |
| Albrecht, J | 1 |
| Xie, P | 1 |
| Liu, S | 1 |
| Huang, Q | 1 |
| Xiong, Z | 1 |
| Deng, J | 1 |
| Tang, C | 1 |
| Xu, K | 1 |
| Zhang, B | 1 |
| He, B | 1 |
| Wang, X | 1 |
| Liu, Z | 1 |
| Wang, J | 2 |
| Zhou, J | 1 |
| Guan, Y | 1 |
| Luan, G | 1 |
| Li, T | 1 |
| Zhai, F | 1 |
| Owen, B | 1 |
| Bichler, E | 1 |
| Benveniste, M | 1 |
| Sano, F | 1 |
| Shigetomi, E | 1 |
| Shinozaki, Y | 1 |
| Tsuzukiyama, H | 1 |
| Saito, K | 1 |
| Mikoshiba, K | 1 |
| Horiuchi, H | 1 |
| Cheung, DL | 1 |
| Nabekura, J | 1 |
| Sugita, K | 1 |
| Aihara, M | 1 |
| Koizumi, S | 1 |
| Behr, C | 1 |
| Lévesque, M | 1 |
| Stroh, T | 1 |
| Avoli, M | 1 |
| Wang, HK | 1 |
| Yan, H | 1 |
| Wang, K | 1 |
| Bittencourt, S | 1 |
| Ferrazoli, E | 1 |
| Valente, MF | 1 |
| Romariz, S | 1 |
| Janisset, NRLL | 1 |
| Macedo, CE | 1 |
| Antonio, BB | 1 |
| Barros, V | 1 |
| Mundim, M | 1 |
| Porcionatto, M | 1 |
| Aarão, MC | 1 |
| Miranda, MF | 1 |
| Rodrigues, AM | 1 |
| de Almeida, AG | 1 |
| Longo, BM | 1 |
| Mello, LE | 2 |
| Hosford, BE | 1 |
| Rowley, S | 1 |
| Liska, JP | 1 |
| Danzer, SC | 1 |
| Russo, I | 1 |
| Bonini, D | 1 |
| Via, LL | 1 |
| Barlati, S | 1 |
| Barbon, A | 1 |
| Kouis, P | 1 |
| Mikroulis, A | 1 |
| Psarropoulou, C | 1 |
| Hanchanale, S | 1 |
| Adkinson, L | 1 |
| Daniel, S | 1 |
| Fleming, M | 1 |
| Oxberry, SG | 1 |
| Hansen, KF | 1 |
| Sakamoto, K | 1 |
| Pelz, C | 1 |
| Impey, S | 1 |
| Obrietan, K | 1 |
| Lusardi, TA | 1 |
| Akula, KK | 1 |
| Coffman, SQ | 1 |
| Ruskin, DN | 1 |
| Masino, SA | 1 |
| Boison, D | 1 |
| Liu, JX | 1 |
| Tang, YC | 1 |
| Liu, Y | 1 |
| Tang, FR | 1 |
| Kim, DS | 1 |
| Kim, JE | 1 |
| Kwak, SE | 1 |
| Choi, KC | 1 |
| Kim, DW | 1 |
| Kwon, OS | 1 |
| Choi, SY | 1 |
| Kang, TC | 1 |
| Young, NA | 1 |
| Vuong, J | 1 |
| Ozen, LJ | 1 |
| Flynn, C | 1 |
| Teskey, GC | 1 |
| Wang, NC | 1 |
| Good, LB | 1 |
| Marsh, ST | 1 |
| Treiman, DM | 1 |
| Määttä, M | 1 |
| Puska, P | 1 |
| Yamashita, F | 1 |
| Hirayama, M | 1 |
| Nakamura, T | 1 |
| Takamori, M | 1 |
| Hori, N | 1 |
| Uchida, K | 1 |
| Hama, T | 1 |
| Sobue, G | 1 |
| Perez-Mendes, P | 1 |
| Blanco, MM | 1 |
| Calcagnotto, ME | 1 |
| Cinini, SM | 1 |
| Bachiega, J | 1 |
| Papoti, D | 1 |
| Covolan, L | 1 |
| Tannus, A | 1 |
| McCloskey, DP | 1 |
| Scharfman, HE | 2 |
| Lauritano, D | 1 |
| Bussolati, A | 1 |
| Baldoni, M | 1 |
| Leonida, A | 1 |
| do Nascimento, AL | 1 |
| Dos Santos, NF | 1 |
| Campos Pelágio, F | 1 |
| Aparecida Teixeira, S | 1 |
| de Moraes Ferrari, EA | 1 |
| Langone, F | 1 |
| Gualtieri, F | 1 |
| Marinelli, C | 1 |
| Longo, D | 1 |
| Pugnaghi, M | 1 |
| Nichelli, PF | 1 |
| Meletti, S | 1 |
| Biagini, G | 1 |
| Kubová, H | 2 |
| Mareš, P | 1 |
| Zhang, X | 1 |
| Cui, SS | 1 |
| Wallace, AE | 1 |
| Hannesson, DK | 1 |
| Schmued, LC | 1 |
| Saucier, DM | 1 |
| Honer, WG | 1 |
| Corcoran, ME | 1 |
| Borges, K | 1 |
| Gearing, M | 1 |
| McDermott, DL | 1 |
| Smith, AB | 1 |
| Almonte, AG | 1 |
| Wainer, BH | 1 |
| Dingledine, R | 1 |
| Shetty, AK | 1 |
| Hattiangady, B | 1 |
| Jung, S | 1 |
| Jones, TD | 1 |
| Lugo, JN | 1 |
| Sheerin, AH | 1 |
| Miller, JW | 1 |
| D'Ambrosio, R | 1 |
| Anderson, AE | 1 |
| Poolos, NP | 1 |
| Arida, RM | 1 |
| Scorza, FA | 1 |
| Peres, CA | 1 |
| Cavalheiro, EA | 1 |
| Plotkin, A | 1 |
| Alagheband, M | 1 |
| Trevino, J | 1 |
| Gulec, G | 1 |
| Noyan, B | 1 |
| Druga, R | 1 |
| Lukasiuk, K | 1 |
| Suchomelová, L | 1 |
| Haugvicová, R | 1 |
| Jirmanová, I | 1 |
| Pitkänen, A | 1 |
| Czechowicz-Janicka, K | 1 |
| Orlewska, E | 1 |
| Tobota, Z | 1 |
| Anielska, E | 1 |
| Dyczkowska, A | 1 |
| Cahill, M | 1 |
| Eustace, P | 1 |
| de Jesus, V | 1 |
| O'Connell, AC | 1 |
| Goodman, JH | 1 |
| Sollas, AL | 1 |
| Croll, SD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Biperiden for Prevention of Epilepsy in Patients With Traumatic Brain Injury[NCT04945213] | Phase 3 | 312 participants (Anticipated) | Interventional | 2023-01-10 | Recruiting | ||
| Effect of Pilocarpine in Patients With Xerostomia[NCT02982577] | Phase 4 | 80 participants (Anticipated) | Interventional | 2016-04-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for pilocarpine and Disease Exacerbation
| Article | Year |
|---|---|
Systematic literature review: xerostomia in advanced cancer patients.
Topics: Acupuncture Therapy; Adult; Chewing Gum; Disease Progression; Humans; Neoplasms; Pilocarpine; Prospe | 2015 |
[Drug therapy for glaucoma].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Disease Progression; Glaucoma; Humans; Intraoc | 2009 |
Scleroderma and CREST syndrome: a case report in dentistry.
Topics: Aged; Combined Modality Therapy; CREST Syndrome; Deglutition Disorders; Dental Caries; Dentures; Dis | 2011 |
Concise review: prospects of stem cell therapy for temporal lobe epilepsy.
Topics: Animals; Brain Injuries; Brain Tissue Transplantation; Cell Differentiation; Disease Models, Animal; | 2007 |
Natural history and prevention of radiation injury.
Topics: Animals; Disease Models, Animal; Disease Progression; Free Radical Scavengers; Humans; Muscarinic Ag | 2000 |
32 other studies available for pilocarpine and Disease Exacerbation
| Article | Year |
|---|---|
Inhibition of Glutamate Release, but Not of Glutamine Recycling to Glutamate, Is Involved in Delaying the Onset of Initial Lithium-Pilocarpine-Induced Seizures in Young Rats by a Non-Convulsive MSO Dose.
Topics: Animals; Brain; Disease Progression; Dose-Response Relationship, Drug; Glutamic Acid; Glutamine; Lit | 2021 |
Deep brain stimulation suppresses epileptic seizures in rats via inhibition of adenosine kinase and activation of adenosine A1 receptors.
Topics: Adenosine Kinase; Animals; Disease Progression; Epilepsy; Male; Pilocarpine; Rats; Rats, Sprague-Daw | 2023 |
Excitatory synaptic transmission in hippocampal area CA1 is enhanced then reduced as chronic epilepsy progresses.
Topics: Animals; CA1 Region, Hippocampal; Chronic Disease; Disease Progression; Epilepsy; Excitatory Postsyn | 2021 |
Reactive astrocyte-driven epileptogenesis is induced by microglia initially activated following status epilepticus.
Topics: Animals; Astrocytes; Calcium Signaling; Disease Models, Animal; Disease Progression; Disease Suscept | 2021 |
Time-dependent evolution of seizures in a model of mesial temporal lobe epilepsy.
Topics: Animals; Brain Waves; Disease Models, Animal; Disease Progression; Electrocorticography; Entorhinal | 2017 |
Dynamic regulation effect of long non-coding RNA-UCA1 on NF-kB in hippocampus of epilepsy rats.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Disease Progression; Epilepsy; Gene Expression Re | 2017 |
Modification of the natural progression of epileptogenesis by means of biperiden in the pilocarpine model of epilepsy.
Topics: Action Potentials; Animals; Autonomic Nervous System; Biperiden; Chronic Disease; Cytokines; Disease | 2017 |
Ablation of peri-insult generated granule cells after epilepsy onset halts disease progression.
Topics: Animals; Disease Models, Animal; Disease Progression; Electroencephalography; Female; Hippocampus; M | 2017 |
AMPA receptor properties are modulated in the early stages following pilocarpine-induced status epilepticus.
Topics: Animals; CA3 Region, Hippocampal; Cerebral Cortex; Dentate Gyrus; Disease Progression; Excitatory Po | 2013 |
A single episode of juvenile status epilepticus reduces the threshold to adult seizures in a stimulus-specific way.
Topics: Animals; Animals, Newborn; Convulsants; Disease Models, Animal; Disease Progression; Female; Male; M | 2014 |
Profiling status epilepticus-induced changes in hippocampal RNA expression using high-throughput RNA sequencing.
Topics: Animals; Base Sequence; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Disease | 2014 |
Ketogenic diet prevents epileptogenesis and disease progression in adult mice and rats.
Topics: Adenosine; Animals; Anticonvulsants; Diet, Ketogenic; Disease Models, Animal; Disease Progression; D | 2015 |
mGluR5-PLCbeta4-PKCbeta2/PKCgamma pathways in hippocampal CA1 pyramidal neurons in pilocarpine model of status epilepticus in mGluR5+/+ mice.
Topics: Animals; Disease Progression; Female; Gene Deletion; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mi | 2008 |
Spatiotemporal characteristics of astroglial death in the rat hippocampo-entorhinal complex following pilocarpine-induced status epilepticus.
Topics: 2-Aminoadipic Acid; Animals; Astrocytes; Cell Death; Cell Proliferation; Convulsants; Disease Models | 2008 |
Motor map expansion in the pilocarpine model of temporal lobe epilepsy is dependent on seizure severity and rat strain.
Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Disease Progression; Dose-Response Re | 2009 |
EEG stages predict treatment response in experimental status epilepticus.
Topics: Analysis of Variance; Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Disease Progressio | 2009 |
Pupillary autonomic dysfunction in multiple system atrophy and Parkinson's disease: an assessment by eye-drop tests.
Topics: 3-Iodobenzylguanidine; Aged; Autonomic Nervous System; Autonomic Nervous System Diseases; Blood Pres | 2010 |
Modeling epileptogenesis and temporal lobe epilepsy in a non-human primate.
Topics: Analysis of Variance; Animals; Anticonvulsants; Benzoxazines; Callithrix; Diazepam; Disease Models, | 2011 |
Progressive, potassium-sensitive epileptiform activity in hippocampal area CA3 of pilocarpine-treated rats with recurrent seizures.
Topics: Action Potentials; Animals; CA3 Region, Hippocampal; Convulsants; Disease Models, Animal; Disease Pr | 2011 |
Neuronal degeneration and gliosis time-course in the mouse hippocampal formation after pilocarpine-induced status epilepticus.
Topics: Analysis of Variance; Animals; Cell Death; Disease Models, Animal; Disease Progression; Fluoresceins | 2012 |
Hypoxia markers are expressed in interneurons exposed to recurrent seizures.
Topics: Animals; Anticonvulsants; Biomarkers; Cell Hypoxia; Cerebral Cortex; Convulsants; Diazepam; Disease | 2013 |
Are morphologic and functional consequences of status epilepticus in infant rats progressive?
Topics: Aggression; Aging; Animals; Animals, Newborn; Antimanic Agents; Atrophy; Behavior, Animal; Brain; Ce | 2013 |
Relations between brain pathology and temporal lobe epilepsy.
Topics: Animals; Brain; Cell Death; Cell Survival; Chronic Disease; Disease Models, Animal; Disease Progress | 2002 |
Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model.
Topics: Amyloid beta-Protein Precursor; Animals; Axons; Behavior, Animal; Cell Death; Disease Models, Animal | 2003 |
Progressive dendritic HCN channelopathy during epileptogenesis in the rat pilocarpine model of epilepsy.
Topics: Animals; Channelopathies; Cyclic Nucleotide-Gated Cation Channels; Dendrites; Disease Models, Animal | 2007 |
The course of untreated seizures in the pilocarpine model of epilepsy.
Topics: Animals; Behavior, Animal; Disease Progression; Electroencephalography; Epilepsy; Incidence; Muscari | 1999 |
Chronic progressive ocular cicatrization.
Topics: Aged; Chronic Disease; Disease Progression; Eyelid Diseases; Humans; Male; Pemphigoid, Benign Mucous | 2000 |
Do recurrent febrile convulsions decrease the threshold for pilocarpine-induced seizures? Effects of nitric oxide.
Topics: Animals; Arginine; Behavior, Animal; Body Temperature; Disease Models, Animal; Disease Progression; | 2001 |
Status epilepticus causes necrotic damage in the mediodorsal nucleus of the thalamus in immature rats.
Topics: Animals; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Apoptosis; Avian Proteins; Basigin; Bl | 2001 |
[Analysis of glaucoma therapy costs in Poland. I--population of the Mazovian District].
Topics: Adult; Aged; Aged, 80 and over; Costs and Cost Analysis; Disease Progression; Female; Glaucoma; Huma | 2000 |
Pupillary autonomic denervation with increasing duration of diabetes mellitus.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autonomic Nervous System Diseases; Case-Control Studies; | 2001 |
Spontaneous limbic seizures after intrahippocampal infusion of brain-derived neurotrophic factor.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Dentate Gyrus; Disease Models, Animal; | 2002 |