pilocarpine has been researched along with Death, Sudden in 7 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Death, Sudden: The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The systemic administration of a potent muscarinic agonist pilocarpine in rats promotes sequential behavioral and electrographic changes that can be divided into 3 distinct periods: (a) an acute period that built up progressively into a limbic status epilepticus and that lasts 24 h, (b) a silent period with a progressive normalization of EEG and behavior which varies from 4 to 44 days, and (c) a chronic period with spontaneous recurrent seizures (SRSs)." | 4.85 | The pilocarpine model of epilepsy: what have we learned? ( Arida, RM; Calderazzo, L; Cavalheiro, EA; Naffah-Mazzacoratti, Mda G; Scerni, DA; Scorza, FA, 2009) |
| "Using the pilocarpine model of epilepsy, we investigated the effects of alcohol consumption on the frequency of seizures in animals with epilepsy as well the underlying a possible association between alcohol intake and sudden unexpected death in epilepsy (SUDEP) occurrence." | 3.75 | Alcohol consumption and sudden unexpected death in epilepsy: experimental approach. ( Arida, RM; Cavalheiro, EA; Cysneiros, RM; de Almeida, AC; Machado, HR; Scorza, FA; Scorzai, CA; Terra, VC, 2009) |
| "Lmx1b(f/f/p) mice had a lower seizure threshold and increased seizure-induced mortality." | 1.40 | Serotonin neurones have anti-convulsant effects and reduce seizure-induced mortality. ( Buchanan, GF; Hajek, MA; Murray, NM; Richerson, GB, 2014) |
| "Among the causes for sudden death in epilepsy, cardiac dysfunction has been an area of interest." | 1.33 | [Analysis of cardiac parameters in animals with epilepsy: possible cause of sudden death?]. ( Arida, RM; Cavalheiro, EA; Colugnati, DB; Cysneiros, RM; de Albuquerque, M; Gomes, PA; Scorza, FA, 2005) |
| "Pilocarpine poisoning was suspected and subsequently confirmed by analysis of urine." | 1.27 | Deaths of two hospital inpatients poisoned by pilocarpine. ( Cordner, SM; Fysh, RR; Gordon, H; Whitaker, SJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buchanan, GF | 1 |
| Murray, NM | 1 |
| Hajek, MA | 1 |
| Richerson, GB | 1 |
| Scorza, FA | 4 |
| Arida, RM | 4 |
| Naffah-Mazzacoratti, Mda G | 1 |
| Scerni, DA | 1 |
| Calderazzo, L | 1 |
| Cavalheiro, EA | 4 |
| Scorzai, CA | 1 |
| Cysneiros, RM | 2 |
| Terra, VC | 1 |
| Machado, HR | 1 |
| de Almeida, AC | 1 |
| Pansani, AP | 1 |
| Colugnati, DB | 2 |
| Sonoda, EY | 1 |
| Cravo, SL | 1 |
| Schoorlemmer, GH | 1 |
| Gomes, PA | 1 |
| de Albuquerque, M | 1 |
| St-Pierre, LS | 1 |
| Parker, GH | 1 |
| Bubenik, GA | 1 |
| Persinger, MA | 1 |
| Cordner, SM | 1 |
| Fysh, RR | 1 |
| Gordon, H | 1 |
| Whitaker, SJ | 1 |
1 review available for pilocarpine and Death, Sudden
| Article | Year |
|---|---|
The pilocarpine model of epilepsy: what have we learned?
Topics: Animals; Death, Sudden; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Exe | 2009 |
6 other studies available for pilocarpine and Death, Sudden
| Article | Year |
|---|---|
Serotonin neurones have anti-convulsant effects and reduce seizure-induced mortality.
Topics: Animals; Death, Sudden; Disease Models, Animal; Electroencephalography; Electroshock; Mice; Mice, Tr | 2014 |
Alcohol consumption and sudden unexpected death in epilepsy: experimental approach.
Topics: Alcohol Drinking; Animals; Death, Sudden; Disease Models, Animal; Epilepsy; Male; Muscarinic Agonist | 2009 |
Tachycardias and sudden unexpected death in epilepsy: a gold rush by an experimental route.
Topics: Analysis of Variance; Animals; Death, Sudden; Disease Models, Animal; Electrocardiography; Epilepsy; | 2010 |
[Analysis of cardiac parameters in animals with epilepsy: possible cause of sudden death?].
Topics: Animals; Death, Sudden; Disease Models, Animal; Electroencephalography; Epilepsy; Heart Rate; Male; | 2005 |
Enhanced mortality of rat pups following inductions of epileptic seizures after perinatal exposures to 5 nT, 7 Hz magnetic fields.
Topics: Animals; Convulsants; Death, Sudden; Electromagnetic Fields; Female; Hippocampus; Lithium; Nitric Ox | 2007 |
Deaths of two hospital inpatients poisoned by pilocarpine.
Topics: Aged; Death, Sudden; Diagnosis, Differential; Dyspnea; England; Female; Food Contamination; Food Ser | 1986 |