Page last updated: 2024-11-08

pilocarpine and Day Blindness

pilocarpine has been researched along with Day Blindness in 22 studies

Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.

Research Excerpts

ExcerptRelevanceReference
"This study aimed to compare the safety and effect on intraocular pressure (IOP) of latanoprost given every evening versus pilocarpine/timolol maleate fixed combination (PTFC) given twice daily in patients with primary open-angle glaucoma (POAG) or ocular hypertension (OH)."9.13Efficacy and safety of latanoprost versus pilocarpine/timolol maleate fixed combination in patients with primary open-angle glaucoma or ocular hypertension. ( Czechowicz-Janicka, K; Kałuzny, BJ; Kałuzny, J; Kecik, D; Sobecki, R; Stewart, JA; Stewart, WC, 2008)
"To present a case series of retinal detachments associated with the use of pilocarpine for presbyopia."8.12Retinal Detachments Associated With Topical Pilocarpine Use for Presbyopia. ( Al-Khersan, H; Flynn, HW; Townsend, JH, 2022)
"In 20 patients with open-angle glaucoma in aphakia or pseudophakia whose intraocular pressure had remained uncontrolled on their current medical therapy, the medication was changed from pilocarpine or carbachol to echothiophate iodide."7.68Intraocular pressure response to the replacement of pilocarpine or carbachol with echothiophate. ( Reichert, RW; Shields, MB, 1991)
"This study aimed to compare the safety and effect on intraocular pressure (IOP) of latanoprost given every evening versus pilocarpine/timolol maleate fixed combination (PTFC) given twice daily in patients with primary open-angle glaucoma (POAG) or ocular hypertension (OH)."5.13Efficacy and safety of latanoprost versus pilocarpine/timolol maleate fixed combination in patients with primary open-angle glaucoma or ocular hypertension. ( Czechowicz-Janicka, K; Kałuzny, BJ; Kałuzny, J; Kecik, D; Sobecki, R; Stewart, JA; Stewart, WC, 2008)
"To present a case series of retinal detachments associated with the use of pilocarpine for presbyopia."4.12Retinal Detachments Associated With Topical Pilocarpine Use for Presbyopia. ( Al-Khersan, H; Flynn, HW; Townsend, JH, 2022)
"In 20 patients with open-angle glaucoma in aphakia or pseudophakia whose intraocular pressure had remained uncontrolled on their current medical therapy, the medication was changed from pilocarpine or carbachol to echothiophate iodide."3.68Intraocular pressure response to the replacement of pilocarpine or carbachol with echothiophate. ( Reichert, RW; Shields, MB, 1991)
"Fifty-four eyes of 45 patients with ocular hypertension developed early glaucomatous optic disc or visual field changes after a mean follow-up of 5."1.29Visual field prognosis in early glaucoma. A long-term clinical follow-up. ( Odberg, T, 1993)
"A man with congenital orbital varices developed progressive ipsilateral visual loss beginning at age 62."1.26Management of a patient with orbital varices, visual loss, and ipsilateral glaucoma. ( Christiansen, J; Di Chiro, G; Gaasterland, D; Kollarits, CR; Yee, RD, 1977)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19905 (22.73)18.7374
1990's8 (36.36)18.2507
2000's6 (27.27)29.6817
2010's2 (9.09)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Al-Khersan, H1
Flynn, HW1
Townsend, JH1
Ferrari, L1
Preziosa, P1
Barcella, V1
Comi, G1
Moiola, L1
Kałuzny, J1
Sobecki, R1
Czechowicz-Janicka, K1
Kecik, D1
Kałuzny, BJ1
Stewart, JA1
Stewart, WC1
Burr, J2
Azuara-Blanco, A2
Avenell, A2
Tuulonen, A1
Dhingra, N1
Watts, MT1
Hori, N1
Takamori, M1
Hirayama, M1
Watanabe, H1
Nakamura, T1
Yamashita, F1
Ito, H1
Mabuchi, N1
Sobue, G1
Odberg, T1
Kushnick, H1
Liebmann, JM1
Ritch, R1
Charles, KC1
Hoffman, RS1
Silén, C1
Faure, M1
Benjamin, KW1
Kollarits, CR1
Gaasterland, D1
Di Chiro, G1
Christiansen, J1
Yee, RD1
Shapiro, AK1
Reichert, RW1
Shields, MB1
Rosenberg, CA1
Adams, SL1
Drance, SM1
Nash, PA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Safety, Tolerability and Preliminary Efficacy of Unilateral Latanoprost-loaded Punctual Plug in Patients With Open Angle Early Visual Field Defects Glaucoma or Ocular Hypertension in Comparison to Xalatan © Eye Drops in the Second Eye[NCT03318146]40 participants (Anticipated)Interventional2018-06-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for pilocarpine and Day Blindness

ArticleYear
Medical versus surgical interventions for open angle glaucoma.
    The Cochrane database of systematic reviews, 2012, Sep-12, Issue:9

    Topics: Aged; Glaucoma, Open-Angle; Humans; Middle Aged; Pilocarpine; Randomized Controlled Trials as Topic;

2012
Medical versus surgical interventions for open angle glaucoma.
    The Cochrane database of systematic reviews, 2005, Apr-18, Issue:2

    Topics: Aged; Glaucoma, Open-Angle; Humans; Middle Aged; Pilocarpine; Randomized Controlled Trials as Topic;

2005
Toxicity of ocular medications.
    International ophthalmology clinics, 1979,Spring, Volume: 19, Issue:1

    Topics: Adult; Aged; Alcohols; Animals; Aqueous Humor; Auditory Perception; Blood; Carbachol; Carbonic Anhyd

1979

Trials

2 trials available for pilocarpine and Day Blindness

ArticleYear
Efficacy and safety of latanoprost versus pilocarpine/timolol maleate fixed combination in patients with primary open-angle glaucoma or ocular hypertension.
    Acta ophthalmologica, 2008, Volume: 86, Issue:8

    Topics: Aged; Drug Administration Schedule; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; In

2008
The dose response of human intraocular pressure to pilocarpine.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1971, Volume: 6, Issue:1

    Topics: Aged; Aqueous Humor; Glaucoma; Headache; Humans; Intraocular Pressure; Middle Aged; Pilocarpine; Tim

1971

Other Studies

17 other studies available for pilocarpine and Day Blindness

ArticleYear
Retinal Detachments Associated With Topical Pilocarpine Use for Presbyopia.
    American journal of ophthalmology, 2022, Volume: 242

    Topics: Humans; Male; Middle Aged; Miotics; Pilocarpine; Presbyopia; Retinal Detachment; Retinal Diseases; R

2022
Subacute visual loss and bilateral fixed mydriasis: an atypical case of giant cell arteritis.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2014, Volume: 35, Issue:8

    Topics: Aged; Blindness; Female; Ganglia, Parasympathetic; Giant Cell Arteritis; Humans; Ischemia; Methylpre

2014
Consultation section. Refractive surgical problem: 3 issues to be discussed: the clinical indications, the surgical procedure, the postoperative findings.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:1

    Topics: Adult; Brimonidine Tartrate; Contact Lenses; Corneal Topography; Diplopia; Drug Administration Sched

2003
Red eyes, reduced vision, and vomiting.
    Postgraduate medical journal, 2003, Volume: 79, Issue:935

    Topics: Aged; Anti-Inflammatory Agents; Corneal Edema; Female; Glaucoma, Angle-Closure; Humans; Miotics; Nau

2003
Pupillary supersensitivity and visual disturbance in Parkinson's disease.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2008, Volume: 18, Issue:1

    Topics: Age Factors; Epinephrine; Female; Humans; Light; Male; Middle Aged; Miotics; Mydriatics; Parkinson D

2008
Visual field prognosis in early glaucoma. A long-term clinical follow-up.
    Acta ophthalmologica, 1993, Volume: 71, Issue:6

    Topics: Acetazolamide; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Longitudinal S

1993
Systemic pilocarpine toxicity from Ocusert leakage.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:11

    Topics: Adolescent; Dizziness; Drug Delivery Systems; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ma

1996
Screening for pupil size in prospective refractive surgery patients.
    Journal of cataract and refractive surgery, 1998, Volume: 24, Issue:3

    Topics: Corneal Transplantation; Humans; Laser Therapy; Myopia; Ophthalmic Solutions; Pilocarpine; Pupil; Vi

1998
Screening for pupil size in prospective refractive surgery patients.
    Journal of cataract and refractive surgery, 1998, Volume: 24, Issue:3

    Topics: Humans; Pilocarpine; Pupil; Refractive Errors; Refractive Surgical Procedures; Vision Disorders

1998
Consultation section. Refractive surgical problem.
    Journal of cataract and refractive surgery, 1999, Volume: 25, Issue:3

    Topics: Adult; Cornea; Corneal Topography; Corneal Transplantation; Eyeglasses; Humans; Hyperopia; Laser The

1999
[Unusual glaucoma of the right eye].
    Duodecim; laaketieteellinen aikakauskirja, 1996, Volume: 112, Issue:15

    Topics: Diagnosis, Differential; Female; Functional Laterality; Glaucoma; Headache; Humans; Middle Aged; Oph

1996
Consultation section. Cataract surgical problem.
    Journal of cataract and refractive surgery, 2000, Volume: 26, Issue:5

    Topics: Aged; Cataract Extraction; Contact Lenses; Contraindications; Female; Glare; Humans; Intraocular Pre

2000
[Not Available].
    Revue d'histoire de la pharmacie, 1977, Volume: 24, Issue:234

    Topics: History, Modern 1601-; Pilocarpine; Vision Disorders

1977
Management of a patient with orbital varices, visual loss, and ipsilateral glaucoma.
    Ophthalmic surgery, 1977, Volume: 8, Issue:5

    Topics: Epinephrine; Exophthalmos; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Orbit; Physica

1977
More on drug-induced blurred vision.
    The American journal of psychiatry, 1977, Volume: 134, Issue:12

    Topics: Lenses; Pilocarpine; Psychotropic Drugs; Vision Disorders

1977
Intraocular pressure response to the replacement of pilocarpine or carbachol with echothiophate.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1991, Volume: 229, Issue:3

    Topics: Aphakia; Aphakia, Postcataract; Carbachol; Echothiophate Iodide; Female; Follow-Up Studies; Glaucoma

1991
Narrow-angle glaucoma presenting as acute, painless visual impairment.
    Annals of emergency medicine, 1991, Volume: 20, Issue:9

    Topics: Acetazolamide; Adult; Emergency Service, Hospital; Female; Glaucoma, Angle-Closure; Gonioscopy; Huma

1991