pilocarpine has been researched along with Caries, Dental in 20 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pilocarpine may have no protective effect on dental caries, periodontitis, or oral candidiasis in patients with pSS." | 7.91 | The effect of pilocarpine on dental caries in patients with primary Sjögren's syndrome: a database prospective cohort study. ( Chen, TH; Chen, YC; Hsu, CY; Hung, KC; Ko, CH; Lin, CY; Lin, MS; Lin, YS, 2019) |
| "Propranolol was given in high (20 mg/kg/day) and low (10 mg/kg/day) doses via osmotic pumps." | 5.29 | The effect of propranolol on salivary gland function and dental caries development in young and aged rats. ( Bowen, WH; O'Connell, AC; Pearson, SK; Van Wuyckhuyse, BC, 1993) |
| "Pilocarpine may have no protective effect on dental caries, periodontitis, or oral candidiasis in patients with pSS." | 3.91 | The effect of pilocarpine on dental caries in patients with primary Sjögren's syndrome: a database prospective cohort study. ( Chen, TH; Chen, YC; Hsu, CY; Hung, KC; Ko, CH; Lin, CY; Lin, MS; Lin, YS, 2019) |
| "We undermitted the patient the dental treatment of Sjogren's syndrome." | 2.47 | Scleroderma and CREST syndrome: a case report in dentistry. ( Baldoni, M; Bussolati, A; Lauritano, D; Leonida, A, 2011) |
| "The causes of xerostomia are numerous, of which the principal are, drug or radiation induced xerostomia and primary an secondary Sjögren's syndrome." | 2.41 | [Dry mouth]. ( Liozon, E; Soria, P; Vidal, E, 2001) |
| "Numerous regimens treat symptoms of xerostomia and associated caries and mucositis." | 2.40 | Manifestations and treatment of xerostomia and associated oral effects secondary to head and neck radiation therapy. ( Garg, AK; Malo, M, 1997) |
| "Early detection and treatment of hyperglycemia and hyposalivation may provide a useful strategy for preventing the dental complications of diabetes and promoting oral health in this population." | 1.38 | Hyperglycemia and xerostomia are key determinants of tooth decay in type 1 diabetic mice. ( Abboud-Werner, S; Chun, YH; Fajardo, R; Harris, SE; Horn, D; Jorgensen, J; Macdougall, M; Mohan, S; Yeh, CK, 2012) |
| "Pilocarpine hydrochloride was shown to have some beneficial effect on quality of life of these patients." | 1.34 | Prevention of oral and salivary gland impairment in irradiated adolescent patients with head and neck cancer: a suggested protocol. ( Aframian, DJ; Davidovich, E; Peretz, B, 2007) |
| "Treatment with pilocarpine hydrochloride may be beneficial in the case of impaired salivary function in patients treated with radioiodine." | 1.33 | Pilocarpine for the treatment of salivary glands' impairment caused by radioiodine therapy for thyroid cancer. ( Aframian, DJ; Helcer, M; Livni, D; Markitziu, A, 2006) |
| "Propranolol was given in high (20 mg/kg/day) and low (10 mg/kg/day) doses via osmotic pumps." | 1.29 | The effect of propranolol on salivary gland function and dental caries development in young and aged rats. ( Bowen, WH; O'Connell, AC; Pearson, SK; Van Wuyckhuyse, BC, 1993) |
| " The findings provide further evidence that chronic administration of propranolol alters salivary composition by decreasing proline-rich proteins and concurrently enhances susceptibility to caries." | 1.28 | The effect of chronic propranolol treatment on salivary composition and caries in the rat. ( Bowen, WH; Falany, JL; Pearson, SK; Tabak, LA; Watson, GE, 1990) |
| "Dental Caries are an uncommon, but significant side effect of the tricyclic antidepressants and other anticholinergic psychoactive drugs." | 1.26 | Rampant dental caries in the treatment of depression. ( Bassuk, E; Schoonover, S, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.00) | 18.7374 |
| 1990's | 6 (30.00) | 18.2507 |
| 2000's | 7 (35.00) | 29.6817 |
| 2010's | 4 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hsu, CY | 1 |
| Hung, KC | 1 |
| Lin, MS | 1 |
| Ko, CH | 1 |
| Lin, YS | 1 |
| Chen, TH | 1 |
| Lin, CY | 1 |
| Chen, YC | 1 |
| López-López, J | 1 |
| Jané Salas, E | 1 |
| Chimenos Küstner, E | 1 |
| Lauritano, D | 1 |
| Bussolati, A | 1 |
| Baldoni, M | 1 |
| Leonida, A | 1 |
| Yeh, CK | 1 |
| Harris, SE | 1 |
| Mohan, S | 1 |
| Horn, D | 1 |
| Fajardo, R | 1 |
| Chun, YH | 1 |
| Jorgensen, J | 1 |
| Macdougall, M | 1 |
| Abboud-Werner, S | 1 |
| Vissink, A | 1 |
| Burlage, FR | 1 |
| Spijkervet, FK | 1 |
| Jansma, J | 1 |
| Coppes, RP | 1 |
| MUHLER, JC | 2 |
| BIXLER, D | 2 |
| SHAFER, WG | 1 |
| Aframian, DJ | 2 |
| Helcer, M | 1 |
| Livni, D | 1 |
| Markitziu, A | 1 |
| Davidovich, E | 1 |
| Peretz, B | 1 |
| Shiboski, CH | 1 |
| Hodgson, TA | 1 |
| Ship, JA | 1 |
| Schiødt, M | 1 |
| O'Connell, AC | 2 |
| Pearson, SK | 3 |
| Bowen, WH | 3 |
| Van Wuyckhuyse, BC | 1 |
| Martínez-Gomis, J | 1 |
| Planas, ME | 1 |
| Planelles, X | 1 |
| Bartrons, R | 1 |
| Sánchez, S | 1 |
| Garg, AK | 1 |
| Malo, M | 1 |
| Vidal, E | 1 |
| Liozon, E | 1 |
| Soria, P | 1 |
| Atkinson, JC | 1 |
| Baum, BJ | 1 |
| Muzyka, BC | 1 |
| Bassuk, E | 1 |
| Schoonover, S | 1 |
| Leach, SA | 1 |
| Connell, R | 1 |
| Watson, GE | 1 |
| Falany, JL | 1 |
| Tabak, LA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness of C02 Microfractionated Laser in Conjunction With Topical Regenerative Therapy in the Management of Vulvo-vaginal Atrophy in Patients With a History of Breast Cancer. Randomized Experimental and Comparative Study.[NCT05585476] | 98 participants (Anticipated) | Interventional | 2022-12-31 | Not yet recruiting | |||
| Yeur-Hur Lai, PhD, RN, School of Nursing, College of Medicine, National Taiwan University[NCT03883152] | 131 participants (Actual) | Observational | 2017-06-27 | Completed | |||
| Xerostomy Treatment in Patients With Sjogren's Syndrome in Chile :A Double Blind Control Trial Comparing Orally Pilocarpine Drops and Artificial Saliva[NCT00438048] | Phase 4 | 76 participants (Actual) | Interventional | 2006-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for pilocarpine and Caries, Dental
| Article | Year |
|---|---|
[Prognosis and treatment of dry mouth. Systematic review].
Topics: Cholinergic Antagonists; Clinical Trials as Topic; Dental Caries; Disease Susceptibility; Double-Bli | 2014 |
Scleroderma and CREST syndrome: a case report in dentistry.
Topics: Aged; Combined Modality Therapy; CREST Syndrome; Deglutition Disorders; Dental Caries; Dentures; Dis | 2011 |
Prevention and treatment of the consequences of head and neck radiotherapy.
Topics: Anti-Bacterial Agents; Cranial Irradiation; Dental Caries; Dysgeusia; Head and Neck Neoplasms; Human | 2003 |
Management of salivary hypofunction during and after radiotherapy.
Topics: Amifostine; Dental Caries; Humans; Muscarinic Agonists; Pilocarpine; Radiation Injuries; Radiation-P | 2007 |
Manifestations and treatment of xerostomia and associated oral effects secondary to head and neck radiation therapy.
Topics: Cariostatic Agents; Chronic Disease; Dental Caries; Fluorides; Gels; Head and Neck Neoplasms; Humans | 1997 |
[Dry mouth].
Topics: Candidiasis, Oral; Dental Caries; Diagnosis, Differential; Humans; Medical History Taking; Muscarini | 2001 |
14 other studies available for pilocarpine and Caries, Dental
| Article | Year |
|---|---|
The effect of pilocarpine on dental caries in patients with primary Sjögren's syndrome: a database prospective cohort study.
Topics: Adult; Candidiasis; Dental Caries; Female; Humans; Male; Middle Aged; Muscarinic Agonists; Outcome A | 2019 |
Hyperglycemia and xerostomia are key determinants of tooth decay in type 1 diabetic mice.
Topics: Amelogenin; Animals; Dental Caries; Dental Enamel Proteins; Diabetes Mellitus, Type 1; Female; Hyper | 2012 |
The effect of pilocarpine on dental caries in the rat.
Topics: Animals; Dental Caries; Pilocarpine; Rats | 1957 |
The effect of pilocarpine in single or divided daily doses on the incidence of dental caries in the rat.
Topics: Animals; Dental Caries; Incidence; Pilocarpine; Rats | 1958 |
Pilocarpine for the treatment of salivary glands' impairment caused by radioiodine therapy for thyroid cancer.
Topics: Adult; Aged; Blood Pressure; Body Temperature; Chronic Disease; Dental Caries; Female; Heart Rate; H | 2006 |
Prevention of oral and salivary gland impairment in irradiated adolescent patients with head and neck cancer: a suggested protocol.
Topics: Adolescent; Child; Clinical Protocols; Cranial Irradiation; Dental Caries; Head and Neck Neoplasms; | 2007 |
Pilocarpine alters caries development in partially-desalivated rats.
Topics: Analysis of Variance; Animals; Cariostatic Agents; Dental Caries; Female; Parotid Gland; Pilocarpine | 1994 |
The effect of propranolol on salivary gland function and dental caries development in young and aged rats.
Topics: Aging; Alveolar Bone Loss; Animals; Dental Caries; Dental Caries Susceptibility; Dental Plaque; Diet | 1993 |
Fluoride and pilocarpine reduce the risk of caries produced by chronic clomipramine treatment in rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Cariostatic Agents; Cholinergic Antagonists; Cl | 1997 |
Salivary enhancement: current status and future therapies.
Topics: Animals; Aquaporin 1; Aquaporins; Blood Group Antigens; Cholinergic Agents; Cranial Irradiation; Den | 2001 |
Assessing salivary gland hypofunction--Part two.
Topics: Anti-Infective Agents, Local; Candidiasis, Oral; Dental Caries; Humans; Maltose; Mastication; Muscar | 2002 |
Rampant dental caries in the treatment of depression.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Dental Caries; Depression; Drug Combinations | 1978 |
Reversal of fissure caries in the albino rat by stimulating salivary flow with pilocarpine.
Topics: Animals; Body Weight; Dental Caries; Dental Fissures; Diet, Cariogenic; Pilocarpine; Rats; Saliva; S | 1990 |
The effect of chronic propranolol treatment on salivary composition and caries in the rat.
Topics: Analysis of Variance; Animals; Dental Caries; Dental Caries Susceptibility; Female; Infusion Pumps; | 1990 |