pilocarpine has been researched along with Cardiomegaly in 2 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we tested the effects of a cholinesterase inhibitor, neostigmine, and a muscarinic cholinergic agonist, pilocarpine, on cardiac hypertrophy and TNF alpha levels during pressure overload." | 7.74 | Neostigmine and pilocarpine attenuated tumour necrosis factor alpha expression and cardiac hypertrophy in the heart with pressure overload. ( Freeling, J; LaCroix, C; Li, YF; Wattier, K, 2008) |
| " In the present study, we tested the effects of a cholinesterase inhibitor, neostigmine, and a muscarinic cholinergic agonist, pilocarpine, on cardiac hypertrophy and TNF alpha levels during pressure overload." | 3.74 | Neostigmine and pilocarpine attenuated tumour necrosis factor alpha expression and cardiac hypertrophy in the heart with pressure overload. ( Freeling, J; LaCroix, C; Li, YF; Wattier, K, 2008) |
| "Status epilepticus was induced in rats by sequential injections of lithium and pilocarpine." | 3.69 | Cardiac hypertrophy secondary to status epilepticus in the rat. ( Rubinstein, BK; Treiman, DM; Walton, NY, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Freeling, J | 1 |
| Wattier, K | 1 |
| LaCroix, C | 1 |
| Li, YF | 1 |
| Walton, NY | 1 |
| Rubinstein, BK | 1 |
| Treiman, DM | 1 |
2 other studies available for pilocarpine and Cardiomegaly
| Article | Year |
|---|---|
Neostigmine and pilocarpine attenuated tumour necrosis factor alpha expression and cardiac hypertrophy in the heart with pressure overload.
Topics: Animals; Animals, Newborn; Body Weight; Cardiomegaly; Cells, Cultured; Constriction, Pathologic; Dru | 2008 |
Cardiac hypertrophy secondary to status epilepticus in the rat.
Topics: Animals; Body Weight; Cardiomegaly; Diazepam; Dizocilpine Maleate; Electroencephalography; Lithium C | 1995 |