pilocarpine has been researched along with Cardiac Hypertrophy in 2 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we tested the effects of a cholinesterase inhibitor, neostigmine, and a muscarinic cholinergic agonist, pilocarpine, on cardiac hypertrophy and TNF alpha levels during pressure overload." | 7.74 | Neostigmine and pilocarpine attenuated tumour necrosis factor alpha expression and cardiac hypertrophy in the heart with pressure overload. ( Freeling, J; LaCroix, C; Li, YF; Wattier, K, 2008) |
| " In the present study, we tested the effects of a cholinesterase inhibitor, neostigmine, and a muscarinic cholinergic agonist, pilocarpine, on cardiac hypertrophy and TNF alpha levels during pressure overload." | 3.74 | Neostigmine and pilocarpine attenuated tumour necrosis factor alpha expression and cardiac hypertrophy in the heart with pressure overload. ( Freeling, J; LaCroix, C; Li, YF; Wattier, K, 2008) |
| "Status epilepticus was induced in rats by sequential injections of lithium and pilocarpine." | 3.69 | Cardiac hypertrophy secondary to status epilepticus in the rat. ( Rubinstein, BK; Treiman, DM; Walton, NY, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Freeling, J | 1 |
| Wattier, K | 1 |
| LaCroix, C | 1 |
| Li, YF | 1 |
| Walton, NY | 1 |
| Rubinstein, BK | 1 |
| Treiman, DM | 1 |
2 other studies available for pilocarpine and Cardiac Hypertrophy
| Article | Year |
|---|---|
Neostigmine and pilocarpine attenuated tumour necrosis factor alpha expression and cardiac hypertrophy in the heart with pressure overload.
Topics: Animals; Animals, Newborn; Body Weight; Cardiomegaly; Cells, Cultured; Constriction, Pathologic; Dru | 2008 |
Cardiac hypertrophy secondary to status epilepticus in the rat.
Topics: Animals; Body Weight; Cardiomegaly; Diazepam; Dizocilpine Maleate; Electroencephalography; Lithium C | 1995 |