pilocarpine has been researched along with Carcinoma, Epidermoid in 8 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Submandibular SGT procedure is superior to pilocarpine in management of radiation-induced xerostomia." | 9.14 | Phase III randomized study: oral pilocarpine versus submandibular salivary gland transfer protocol for the management of radiation-induced xerostomia. ( Barnaby, P; Black, M; Butler, J; Ghosh, S; Harris, J; Hier, M; Jha, N; Kerr, P; Seikaly, H; Sultanem, K; Sutherland, D; Williams, D, 2009) |
| "This study was undertaken to determine whether standard salivary gland scintigraphy may be used for the objective assessment of salivary gland sialogogues, in particular oral pilocarpine, in the treatment of post-radiotherapy xerostomia." | 7.70 | Does salivary gland scintigraphy predict response to pilocarpine in patients with post-radiotherapy xerostomia? ( Allan, E; Collins, CD; Cooper, RA; Cowan, RA; Gupta, NK; Hillel, PG; Jeans, SP; Owens, SE; Roberts, JK; Slevin, NJ, 1999) |
| "Submandibular SGT procedure is superior to pilocarpine in management of radiation-induced xerostomia." | 5.14 | Phase III randomized study: oral pilocarpine versus submandibular salivary gland transfer protocol for the management of radiation-induced xerostomia. ( Barnaby, P; Black, M; Butler, J; Ghosh, S; Harris, J; Hier, M; Jha, N; Kerr, P; Seikaly, H; Sultanem, K; Sutherland, D; Williams, D, 2009) |
| "To investigate the effect of concomitant administration of pilocarpine during radiotherapy for head-and-neck squamous cell carcinoma (HNSCC) on postradiotherapy xerostomia." | 5.13 | Protection of salivary function by concomitant pilocarpine during radiotherapy: a double-blind, randomized, placebo-controlled study. ( Burlage, FR; Coppes, RP; Kampinga, HH; Langendijk, JA; Roesink, JM; Stokman, MA; Terhaard, C; van Luijk, P; Vissink, A, 2008) |
| "This study was undertaken to determine whether standard salivary gland scintigraphy may be used for the objective assessment of salivary gland sialogogues, in particular oral pilocarpine, in the treatment of post-radiotherapy xerostomia." | 3.70 | Does salivary gland scintigraphy predict response to pilocarpine in patients with post-radiotherapy xerostomia? ( Allan, E; Collins, CD; Cooper, RA; Cowan, RA; Gupta, NK; Hillel, PG; Jeans, SP; Owens, SE; Roberts, JK; Slevin, NJ, 1999) |
| "Xerostomia was measured on a linear analog scale." | 2.71 | Postradiotherapy quality of life for head-and-neck cancer patients is independent of xerostomia. ( Cummings, B; Lockwood, G; O'Sullivan, B; Ringash, J; Waldron, J; Warde, P, 2005) |
| "Pilocarpine is a useful agent as a treatment of radiation-induced xerostomia in head and neck cancer patients." | 2.43 | Evaluation, prevention and management of radiotherapy-induced xerostomia in head and neck cancer patients. ( de Castro, G; Federico, MH, 2006) |
| "The survival of squamous carcinoma tumor cells, line SCC-25, following the exposure of cells to pilocarpine at concentration of 0-100 ng/ml given for 0-1 h prior to radiation at dose of 0-20 Gy was determined by an in vitro colony-formation assay." | 1.30 | Pilocarpine, a salivary gland radioprotectant, does not inhibit cytotoxic effect of gamma-radiation on squamous cell carcinoma in vitro. ( Herman, TS; MacDonald, JR; Roberts, K; Woynarowska, B, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jha, N | 1 |
| Seikaly, H | 1 |
| Harris, J | 1 |
| Williams, D | 1 |
| Sultanem, K | 1 |
| Hier, M | 1 |
| Ghosh, S | 1 |
| Black, M | 1 |
| Butler, J | 1 |
| Sutherland, D | 1 |
| Kerr, P | 1 |
| Barnaby, P | 1 |
| Ringash, J | 1 |
| Warde, P | 1 |
| Lockwood, G | 1 |
| O'Sullivan, B | 1 |
| Waldron, J | 1 |
| Cummings, B | 1 |
| de Castro, G | 1 |
| Federico, MH | 1 |
| Burlage, FR | 1 |
| Roesink, JM | 1 |
| Kampinga, HH | 2 |
| Coppes, RP | 2 |
| Terhaard, C | 1 |
| Langendijk, JA | 1 |
| van Luijk, P | 1 |
| Stokman, MA | 1 |
| Vissink, A | 1 |
| Woynarowska, B | 1 |
| Roberts, K | 1 |
| Herman, TS | 1 |
| MacDonald, JR | 1 |
| Niedermeier, W | 1 |
| Matthaeus, C | 1 |
| Meyer, C | 1 |
| Staar, S | 1 |
| Müller, RP | 1 |
| Schulze, HJ | 1 |
| Cooper, RA | 1 |
| Cowan, RA | 1 |
| Owens, SE | 1 |
| Jeans, SP | 1 |
| Roberts, JK | 1 |
| Hillel, PG | 1 |
| Slevin, NJ | 1 |
| Allan, E | 1 |
| Gupta, NK | 1 |
| Collins, CD | 1 |
| Licht, R | 1 |
1 review available for pilocarpine and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Evaluation, prevention and management of radiotherapy-induced xerostomia in head and neck cancer patients.
Topics: Amifostine; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cytoplasmic Granules; Free Radical S | 2006 |
4 trials available for pilocarpine and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Phase III randomized study: oral pilocarpine versus submandibular salivary gland transfer protocol for the management of radiation-induced xerostomia.
Topics: Administration, Oral; Aged; Carcinoma, Squamous Cell; Disease-Free Survival; Female; Head and Neck N | 2009 |
Postradiotherapy quality of life for head-and-neck cancer patients is independent of xerostomia.
Topics: Carcinoma, Squamous Cell; Confidence Intervals; Female; Head and Neck Neoplasms; Health Status; Huma | 2005 |
Protection of salivary function by concomitant pilocarpine during radiotherapy: a double-blind, randomized, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Double-Blind Method; Female; Head and Neck Neopla | 2008 |
Radiation-induced hyposalivation and its treatment with oral pilocarpine.
Topics: Carcinoma, Squamous Cell; Cranial Irradiation; Female; Head and Neck Neoplasms; Humans; Male; Middle | 1998 |
3 other studies available for pilocarpine and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Pilocarpine, a salivary gland radioprotectant, does not inhibit cytotoxic effect of gamma-radiation on squamous cell carcinoma in vitro.
Topics: Carcinoma, Squamous Cell; Cell Survival; Humans; Pilocarpine; Radiation Dosage; Radiation-Protective | 1997 |
Does salivary gland scintigraphy predict response to pilocarpine in patients with post-radiotherapy xerostomia?
Topics: Administration, Oral; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Middl | 1999 |
Salivary gland-sparing prophylactic pilocarpine treatment has no effect on tumor regrowth after irradiation.
Topics: Animals; Carcinoma, Squamous Cell; Cell Division; Dose-Response Relationship, Radiation; Humans; Mic | 2002 |