pilocarpine has been researched along with Brain Disorders in 9 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present work studied the effect of a calcium channel blocker (nimodipine) on rat behavioural changes and brain lesions observed after seizures induced by high doses of pilocarpine (400 mg/kg, s." | 7.69 | Inhibitory action of a calcium channel blocker (nimodipine) on seizures and brain damage induced by pilocarpine and lithium-pilocarpine in rats. ( Aguiar, LM; de Bruin, VM; de Pinho, RS; de Sousa, FC; Marinho, MM; Viana, GS, 1997) |
| " As in patients, the consequences of the lithium-pilocarpine-induced status epilepticus (SE) are age dependent, and only a subset of 21-day-old rats will develop epilepsy." | 3.71 | Predictive value of cortical injury for the development of temporal lobe epilepsy in 21-day-old rats: an MRI approach using the lithium-pilocarpine model. ( Leroy, C; Namer, IJ; Nehlig, A; Roch, C, 2002) |
| "The present work studied the effect of a calcium channel blocker (nimodipine) on rat behavioural changes and brain lesions observed after seizures induced by high doses of pilocarpine (400 mg/kg, s." | 3.69 | Inhibitory action of a calcium channel blocker (nimodipine) on seizures and brain damage induced by pilocarpine and lithium-pilocarpine in rats. ( Aguiar, LM; de Bruin, VM; de Pinho, RS; de Sousa, FC; Marinho, MM; Viana, GS, 1997) |
| "Microinjections of the cholinergic agonists, carbachol and bethanechol, either into the amygdala or into the dorsal hippocampus produced sustained limbic seizures and brain damage in rats." | 3.66 | Cholinomimetics produce seizures and brain damage in rats. ( Czuczwar, SJ; Kleinrok, Z; Turski, L; Turski, WA, 1983) |
| "pilocarpine were also reduced 6 h, 2, and 7 days after an AV3V lesion (143 +/- 19, 273 +/- 14, and 322 +/- 17 mg/7 min, respectively), but not after 15 days (450 +/- 28 mg/7 min)." | 1.29 | Involvement of the central nervous system in the salivary secretion induced by pilocarpine in rats. ( Camargo, LA; Colombari, E; de Luca Júnior, LA; Deróbio, JG; Mattos Filho, TR; Menani, JV; Renzi, A; Saad, WA; Silveira, JE, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roch, C | 1 |
| Leroy, C | 1 |
| Nehlig, A | 1 |
| Namer, IJ | 1 |
| MANGOS, JA | 1 |
| LOBECK, CC | 1 |
| Setkowicz, Z | 1 |
| Janicka, D | 1 |
| Kowalczyk, A | 1 |
| Turlej, A | 1 |
| Janeczko, K | 1 |
| Turski, WA | 2 |
| Czuczwar, SJ | 1 |
| Kleinrok, Z | 1 |
| Turski, L | 2 |
| Cavalheiro, EA | 1 |
| Bortolotto, ZA | 1 |
| Mello, LM | 1 |
| Schwarz, M | 1 |
| Renzi, A | 1 |
| Colombari, E | 1 |
| Mattos Filho, TR | 1 |
| Silveira, JE | 1 |
| Saad, WA | 1 |
| Camargo, LA | 1 |
| de Luca Júnior, LA | 1 |
| Deróbio, JG | 1 |
| Menani, JV | 1 |
| Fujikawa, DG | 1 |
| Marinho, MM | 1 |
| de Bruin, VM | 1 |
| de Sousa, FC | 1 |
| Aguiar, LM | 1 |
| de Pinho, RS | 1 |
| Viana, GS | 1 |
| Boyd, EM | 1 |
1 review available for pilocarpine and Brain Disorders
| Article | Year |
|---|---|
Encephalopathy in toxicity tests on laboratory animals.
Topics: Animals; Aspirin; Atropine; Behavior, Animal; Brain Damage, Chronic; Brain Diseases; Caffeine; Casei | 1971 |
8 other studies available for pilocarpine and Brain Disorders
| Article | Year |
|---|---|
Predictive value of cortical injury for the development of temporal lobe epilepsy in 21-day-old rats: an MRI approach using the lithium-pilocarpine model.
Topics: Age Factors; Animals; Brain Diseases; Cerebral Cortex; Disease Models, Animal; Entorhinal Cortex; Ep | 2002 |
STUDIES OF SUSTAINED HYPONATREMIA DUE TO CENTRAL NERVOUS SYSTEM INFECTION.
Topics: Alcohols; Anti-Bacterial Agents; Brain Abscess; Brain Diseases; Drug Therapy; Ethanol; Humans; Hydro | 1964 |
Congenital brain dysplasias of different genesis can differently affect susceptibility to pilocarpine- or kainic acid-induced seizures in the rat.
Topics: Animals; Behavior, Animal; Brain Diseases; Convulsants; Dose-Response Relationship, Drug; Electroenc | 2005 |
Cholinomimetics produce seizures and brain damage in rats.
Topics: Amygdala; Animals; Bethanechol; Bethanechol Compounds; Brain; Brain Diseases; Carbachol; Hippocampus | 1983 |
Seizures produced by pilocarpine in mice: a behavioral, electroencephalographic and morphological analysis.
Topics: Animals; Brain; Brain Diseases; Cholinergic Fibers; Disease Models, Animal; Electroencephalography; | 1984 |
Involvement of the central nervous system in the salivary secretion induced by pilocarpine in rats.
Topics: Animals; Brain Diseases; Cerebral Ventricles; Injections; Injections, Intraperitoneal; Male; Neural | 1993 |
The temporal evolution of neuronal damage from pilocarpine-induced status epilepticus.
Topics: Animals; Brain Diseases; Hippocampus; Male; Neurons; Pilocarpine; Rats; Rats, Wistar; Status Epilept | 1996 |
Inhibitory action of a calcium channel blocker (nimodipine) on seizures and brain damage induced by pilocarpine and lithium-pilocarpine in rats.
Topics: Animals; Atropine; Brain Diseases; Lithium; Male; Nimodipine; Pilocarpine; Rats; Rats, Wistar; Seizu | 1997 |