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pilocarpine and Audiogenic Epilepsy

pilocarpine has been researched along with Audiogenic Epilepsy in 5 studies

Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.

Research Excerpts

ExcerptRelevanceReference
"The effects of ALAC administered per os were evaluated by standard protocols against audiogenic seizures in Genetic Epilepsy Prone Rats (GEPR-9 rats), maximal electroshock (MES)-induced seizures in rats, pilocarpine-induced seizures in mice, spontaneous chronic seizures in mice exposed to pilocarpine-induced status epilepticus (SE), and absence seizures in WAG/Rij rats."7.77Preclinical activity profile of α-lactoalbumin, a whey protein rich in tryptophan, in rodent models of seizures and epilepsy. ( Citraro, R; De Fazio, S; De Sarro, G; Mainardi, P; Perucca, E; Raggio, R; Russo, E; Scicchitano, F, 2011)
" Here, we induced lithium-pilocarpine status epilepticus (SE) in Genetic Absence Epilepsy Rats from Strasbourg (GAERS) or in Wistar audiogenic sensitive (AS) rats."7.74The role of the inherited genetic background on the consequences of lithium-pilocarpine status epilepticus: study in Genetic Absence Epilepsy Rats from Strasbourg and Wistar audiogenic rats. ( Ferrandon, A; Hanaya, R; Koning, E; Nehlig, A, 2008)
"The administration of pilocarpine (PILO) is widely recognized as resulting in an experimental model of temporal lobe epilepsy; it is characterized by induction of status epilepticus (SE) and spontaneous recurrent seizures after a latent period."7.72Neuroethological study of status epilepticus induced by systemic pilocarpine in Wistar audiogenic rats (WAR strain). ( Furtado, Mde A; Garcia-Cairasco, N; Oliveira, JA; Rossetti, F, 2004)
"The effects of ALAC administered per os were evaluated by standard protocols against audiogenic seizures in Genetic Epilepsy Prone Rats (GEPR-9 rats), maximal electroshock (MES)-induced seizures in rats, pilocarpine-induced seizures in mice, spontaneous chronic seizures in mice exposed to pilocarpine-induced status epilepticus (SE), and absence seizures in WAG/Rij rats."3.77Preclinical activity profile of α-lactoalbumin, a whey protein rich in tryptophan, in rodent models of seizures and epilepsy. ( Citraro, R; De Fazio, S; De Sarro, G; Mainardi, P; Perucca, E; Raggio, R; Russo, E; Scicchitano, F, 2011)
" Here, we induced lithium-pilocarpine status epilepticus (SE) in Genetic Absence Epilepsy Rats from Strasbourg (GAERS) or in Wistar audiogenic sensitive (AS) rats."3.74The role of the inherited genetic background on the consequences of lithium-pilocarpine status epilepticus: study in Genetic Absence Epilepsy Rats from Strasbourg and Wistar audiogenic rats. ( Ferrandon, A; Hanaya, R; Koning, E; Nehlig, A, 2008)
"The administration of pilocarpine (PILO) is widely recognized as resulting in an experimental model of temporal lobe epilepsy; it is characterized by induction of status epilepticus (SE) and spontaneous recurrent seizures after a latent period."3.72Neuroethological study of status epilepticus induced by systemic pilocarpine in Wistar audiogenic rats (WAR strain). ( Furtado, Mde A; Garcia-Cairasco, N; Oliveira, JA; Rossetti, F, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hanaya, R1
Koning, E1
Ferrandon, A1
Nehlig, A1
Rubio, C1
Rubio-Osornio, M1
Retana-Márquez, S1
Verónica Custodio, ML1
Paz, C1
Citraro, R1
Scicchitano, F1
De Fazio, S1
Raggio, R1
Mainardi, P1
Perucca, E1
De Sarro, G1
Russo, E1
Garcia-Cairasco, N1
Rossetti, F1
Oliveira, JA1
Furtado, Mde A1
White, HS1
Watson, WP1
Hansen, SL1
Slough, S1
Perregaard, J1
Sarup, A1
Bolvig, T1
Petersen, G1
Larsson, OM1
Clausen, RP1
Frølund, B1
Falch, E1
Krogsgaard-Larsen, P1
Schousboe, A1

Reviews

1 review available for pilocarpine and Audiogenic Epilepsy

ArticleYear
In vivo experimental models of epilepsy.
    Central nervous system agents in medicinal chemistry, 2010, Dec-01, Volume: 10, Issue:4

    Topics: Aluminum Hydroxide; Animals; Bicuculline; Cobalt; Convulsants; Disease Models, Animal; Electroshock;

2010

Other Studies

4 other studies available for pilocarpine and Audiogenic Epilepsy

ArticleYear
The role of the inherited genetic background on the consequences of lithium-pilocarpine status epilepticus: study in Genetic Absence Epilepsy Rats from Strasbourg and Wistar audiogenic rats.
    Neurobiology of disease, 2008, Volume: 31, Issue:3

    Topics: Animals; Antimanic Agents; Cell Death; Convulsants; Disease Models, Animal; Electroencephalography;

2008
Preclinical activity profile of α-lactoalbumin, a whey protein rich in tryptophan, in rodent models of seizures and epilepsy.
    Epilepsy research, 2011, Volume: 95, Issue:1-2

    Topics: Amino Acids; Animals; Carbamazepine; Convulsants; Drug Evaluation, Preclinical; Electroshock; Epilep

2011
Neuroethological study of status epilepticus induced by systemic pilocarpine in Wistar audiogenic rats (WAR strain).
    Epilepsy & behavior : E&B, 2004, Volume: 5, Issue:4

    Topics: Acoustic Stimulation; Animals; Behavior, Animal; Disease Models, Animal; Epilepsy, Reflex; Limbic Sy

2004
First demonstration of a functional role for central nervous system betaine/{gamma}-aminobutyric acid transporter (mGAT2) based on synergistic anticonvulsant action among inhibitors of mGAT1 and mGAT2.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:2

    Topics: Acoustic Stimulation; Acyltransferases; Amygdala; Animals; Anticonvulsants; Behavior, Animal; Cells,

2005