pilocarpine has been researched along with Atrophy in 9 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Topical gel formulations containing pilocarpine had no effect on atrophy of the vaginal epithelium in the castrated female rats." | 7.83 | Effect of a gel containing pilocarpine on vaginal atrophy in castrated rats. ( Borges, CS; Conde, AM; Costa-Silva, DR; Cunha-Nunes, LC; da Conceição Barros-Oliveira, M; da-Silva, BB; de Deus-Lages, LP; de Moura-Leal, AC; de Sousa, GV; de Sousa-Lages, CA; Escórcio-Dourado, CS; Sampaio, FA, 2016) |
| "Systemic administration of pilocarpine, which results in status epilepticus followed by recurrent seizures in rats, is a widely used experimental model of chronic limbic epilepsy." | 7.70 | Persistence and atrophy of septal/diagonal band neurons expressing the p75 neurotrophin receptor in pilocarpine-induced chronic epilepsy in the rat. ( Amado, D; Bentivoglio, M; Cavalheiro, EA; Correia, L, 1998) |
| "The present study examined whether status epilepticus (SE) induced by LiCl-pilocarpine in immature rats (postnatal day [P]12) interferes with normal development; leads to progressive epileptogenesis, or cognitive decline and to pathology similar to that seen in human temporal lobe epilepsy." | 3.79 | Are morphologic and functional consequences of status epilepticus in infant rats progressive? ( Kubová, H; Mareš, P, 2013) |
| "Time-dependent atrophy of cerebral space and enlargement of the lateral ventricles were noted in healthy rats 1 to 100 days after the induction of seizures by a single systemic injection of lithium and pilocarpine." | 3.70 | Ventricular dilation over several weeks following induction of excitotoxic (systemic lithium/pilocarpine) lesions: potential role of damage to the substantia nigra reticulata. ( Desjardins, D; Eastman, A; Peredery, O; Persinger, MA, 1998) |
| "Systemic administration of pilocarpine, which results in status epilepticus followed by recurrent seizures in rats, is a widely used experimental model of chronic limbic epilepsy." | 3.70 | Persistence and atrophy of septal/diagonal band neurons expressing the p75 neurotrophin receptor in pilocarpine-induced chronic epilepsy in the rat. ( Amado, D; Bentivoglio, M; Cavalheiro, EA; Correia, L, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Sousa-Lages, CA | 1 |
| de Deus-Lages, LP | 1 |
| de Sousa, GV | 1 |
| de Moura-Leal, AC | 1 |
| Conde, AM | 1 |
| Costa-Silva, DR | 1 |
| da Conceição Barros-Oliveira, M | 1 |
| Borges, CS | 1 |
| Escórcio-Dourado, CS | 1 |
| Sampaio, FA | 1 |
| Cunha-Nunes, LC | 1 |
| da-Silva, BB | 1 |
| Kubová, H | 1 |
| Mareš, P | 1 |
| Bergeå, B | 1 |
| Bodin, L | 1 |
| Svedbergh, B | 1 |
| Persinger, MA | 1 |
| Peredery, O | 1 |
| Desjardins, D | 1 |
| Eastman, A | 1 |
| Correia, L | 1 |
| Amado, D | 1 |
| Cavalheiro, EA | 1 |
| Bentivoglio, M | 1 |
| Barishak, YR | 1 |
| Beemer, AM | 1 |
| Egyed, MN | 1 |
| Shlosberg, A | 1 |
| Eilat, A | 1 |
| Scott, J | 1 |
| Berry, MR | 1 |
| Gunn, DL | 1 |
| Woods, K | 1 |
| Gasset, AR | 1 |
| Worthen, DM | 1 |
| Hunt, WL | 1 |
1 trial available for pilocarpine and Atrophy
| Article | Year |
|---|---|
Primary argon laser trabeculoplasty vs pilocarpine. IV. Long-term effects on optic nerve head.
Topics: Aged; Atrophy; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Longitudin | 1995 |
8 other studies available for pilocarpine and Atrophy
| Article | Year |
|---|---|
Effect of a gel containing pilocarpine on vaginal atrophy in castrated rats.
Topics: Animals; Atrophy; Epithelium; Female; Models, Animal; Muscarinic Agonists; Pilocarpine; Random Alloc | 2016 |
Are morphologic and functional consequences of status epilepticus in infant rats progressive?
Topics: Aggression; Aging; Animals; Animals, Newborn; Antimanic Agents; Atrophy; Behavior, Animal; Brain; Ce | 2013 |
Ventricular dilation over several weeks following induction of excitotoxic (systemic lithium/pilocarpine) lesions: potential role of damage to the substantia nigra reticulata.
Topics: Animals; Atrophy; Brain; Cerebral Ventricles; Lithium; Male; Nerve Degeneration; Neurotoxins; Piloca | 1998 |
Persistence and atrophy of septal/diagonal band neurons expressing the p75 neurotrophin receptor in pilocarpine-induced chronic epilepsy in the rat.
Topics: Animals; Antibodies; Atrophy; Cholinergic Fibers; Chronic Disease; Epilepsy; Hippocampus; Male; Neur | 1998 |
Histology of the iris in geese and ducks photosensitized by ingestion of Ammi majus seeds.
Topics: Animals; Atrophy; Constriction; Dilatation, Pathologic; Ducks; Geese; Iris; Magnoliopsida; Methoxsal | 1975 |
The effects of a liquid diet on initial and sustained, stimulated parotid salivary secretion and on parotid structure in the rat.
Topics: Animals; Atrophy; Diet; Isoproterenol; Male; Microscopy, Electron; Parotid Gland; Pilocarpine; Rats; | 1990 |
Keratoconus and Chandler's syndrome.
Topics: Acetazolamide; Adult; Atrophy; Corneal Dystrophies, Hereditary; Edema; Epinephrine; Eye Diseases; Fl | 1974 |
Responses of rat testes and accessory glands to testosterone, pilocarpine and copulation.
Topics: Animals; Atrophy; Body Weight; Copulation; Depression, Chemical; Leydig Cells; Male; Organ Size; Pil | 1969 |