pilocarpine has been researched along with Anxiety in 30 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The anxiety induced by pilocarpine was also significantly (P < 0." | 8.12 | Anticonvulsant effects of Cymbopogon giganteus extracts with possible effects on fully kindled seizures and anxiety in experimental rodent model of mesio-temporal epilepsy induced by pilocarpine. ( Bum, EN; Kouemou Emegam, N; Neteydji, S; Pale, S; Taiwe, GS, 2022) |
| "5h with pilocarpine to study anxiety-related behaviors, changes in the electroencephalogram of the cerebral cortex and hippocampus, and expression of hippocampal proteins." | 7.83 | Dual mechanisms of rapid expression of anxiety-related behavior in pilocarpine-treated epileptic mice. ( Iida, Y; Itakura, M; Miyaoka, H; Ohkido, T; Otsuka, S; Saito, M; Takahashi, M; Watanabe, S; Yamamori, S, 2016) |
| "Subconvulsant doses of pilocarpine promote long-lasting alterations on neural circuitry, reflected by an increased theta activity in the hippocampus and an anxiety-like profile of rats evaluated 1 month after the treatment which is independent of seizure occurrence and is not related to changes in glutamate uptake or hippocampal damage." | 7.79 | Anxiogenic-like profile of Wistar adult rats based on the pilocarpine model: an animal model for trait anxiety? ( Carobrez, AP; De Lima, TC; Duarte, FS; Duzzioni, M; Ern, AL; Gavioli, EC; Hoeller, AA; Lemos, T; Piermartiri, TC; Silva, NM; Tasca, CI, 2013) |
| ")-injected GLP-1 on pilocarpine-induced seizures, anxiety and locomotor and exploratory activity in rat." | 7.76 | Effects of centrally-injected glucagon-like peptide-1 on pilocarpine-induced seizures, anxiety and locomotor and exploratory activity in rat. ( Gulec, G; Isbil-Buyukcoskun, N; Kahveci, N, 2010) |
| "This study investigated putative correlations among behavioral changes and: (1) neuronal loss, (2) hippocampal mossy fiber sprouting, and (3) reactive astrogliosis in adult rats submitted to early-life LiCl-pilocarpine-induced status epilepticus (SE)." | 7.74 | Effects of early-life LiCl-pilocarpine-induced status epilepticus on memory and anxiety in adult rats are associated with mossy fiber sprouting and elevated CSF S100B protein. ( da Silva, MC; de Oliveira, DL; e Souza, TM; Fischer, A; Gonçalves, CA; Jorge, RS; Leite, M; Quillfeldt, JA; Souza, DO; Wofchuk, S, 2008) |
| "Ketamine post-SE onset treatment prevented neuronal death in all regions assessed." | 5.38 | Ketamine reduces neuronal degeneration and anxiety levels when administered during early life-induced status epilepticus in rats. ( Córdova, SD; de Oliveira, DL; Loss, CM, 2012) |
| " The anxiety induced by pilocarpine was also significantly (P < 0." | 4.12 | Anticonvulsant effects of Cymbopogon giganteus extracts with possible effects on fully kindled seizures and anxiety in experimental rodent model of mesio-temporal epilepsy induced by pilocarpine. ( Bum, EN; Kouemou Emegam, N; Neteydji, S; Pale, S; Taiwe, GS, 2022) |
| " In the present study, we tested the effects of NRP2945 on the development of epilepsy (epileptogenesis) and on chronic, spontaneous seizures, by using the pilocarpine model of temporal lobe epilepsy." | 4.02 | Anti-epileptogenic effect of NRP2945 in the pilocarpine model of temporal lobe epilepsy. ( Falcicchia, C; Guarino, A; Ingusci, S; Lovisari, F; Marino, P; Sieg, F; Simonato, M; Soukupova, M; Thomas, M, 2021) |
| "The results of present study concluded that GBbf treatment suppressed lithium-pilocarpine induced spontaneous recurrent seizures severity and incidence with improved cognitive functions, reduced anxiety-like behavior and aggression." | 3.85 | Ginkgo biloba L. attenuates spontaneous recurrent seizures and associated neurological conditions in lithium-pilocarpine rat model of temporal lobe epilepsy through inhibition of mammalian target of rapamycin pathway hyperactivation. ( Mazumder, AG; Patial, V; Sharma, P; Singh, D, 2017) |
| " Using the lithium-pilocarpine model of temporal lobe epilepsy (TLE), we recently showed that inhibition of this receptor during the first ten days after pilocarpine-induced status epilepticus (SE) results in substantial anti-epileptogenic and neuroprotective effects." | 3.85 | Effects of protease-activated receptor 1 inhibition on anxiety and fear following status epilepticus. ( Bogovyk, R; Fedoriuk, M; Holmes, GL; Isaev, D; Isaeva, E; Krishtal, O; Lunko, O, 2017) |
| " Previous findings provided new insights into the underlying mechanisms of long-term anxiety, showing that rats injected with a single systemic dose of pilocarpine--a muscarinic receptor (mAChR) agonist--displayed persistent anxiogenic-like responses when evaluated in different behavioral tests and time-points (24 h up to 3 months later)." | 3.83 | The Role of Hippocampal NMDA Receptors in Long-Term Emotional Responses following Muscarinic Receptor Activation. ( Bicca, MA; Bortolotto, ZA; Collingridge, GL; Costa, AP; de Lima, TC; Hoeller, AA; Lach, G; Lightman, SL; Matheus, FC; Spiga, F; Walz, R, 2016) |
| "5h with pilocarpine to study anxiety-related behaviors, changes in the electroencephalogram of the cerebral cortex and hippocampus, and expression of hippocampal proteins." | 3.83 | Dual mechanisms of rapid expression of anxiety-related behavior in pilocarpine-treated epileptic mice. ( Iida, Y; Itakura, M; Miyaoka, H; Ohkido, T; Otsuka, S; Saito, M; Takahashi, M; Watanabe, S; Yamamori, S, 2016) |
| " monnieri extract in ameliorating pilocarpine induced temporal lobe epilepsy through regulation of 5-HT2C and NMDA receptors in cerebral cortex." | 3.81 | Alteration in 5-HT₂C, NMDA receptor and IP3 in cerebral cortex of epileptic rats: restorative role of Bacopa monnieri. ( Abraham, PM; Anju, TR; Krishnakumar, A; Paulose, CS, 2015) |
| "Subconvulsant doses of pilocarpine promote long-lasting alterations on neural circuitry, reflected by an increased theta activity in the hippocampus and an anxiety-like profile of rats evaluated 1 month after the treatment which is independent of seizure occurrence and is not related to changes in glutamate uptake or hippocampal damage." | 3.79 | Anxiogenic-like profile of Wistar adult rats based on the pilocarpine model: an animal model for trait anxiety? ( Carobrez, AP; De Lima, TC; Duarte, FS; Duzzioni, M; Ern, AL; Gavioli, EC; Hoeller, AA; Lemos, T; Piermartiri, TC; Silva, NM; Tasca, CI, 2013) |
| ")-injected GLP-1 on pilocarpine-induced seizures, anxiety and locomotor and exploratory activity in rat." | 3.76 | Effects of centrally-injected glucagon-like peptide-1 on pilocarpine-induced seizures, anxiety and locomotor and exploratory activity in rat. ( Gulec, G; Isbil-Buyukcoskun, N; Kahveci, N, 2010) |
| " An epilepsy model was induced in female rats by administration of pilocarpine." | 3.76 | Behavioral evaluation of adult rats exposed in utero to maternal epileptic seizures. ( Amado, D; Arganãraz, GA; Cavalheiro, EA; Frussa-Filho, R; Lima, DC; Naffah-Mazzacoratti, Mda G; Vale, TG; Varella, PP, 2010) |
| " Temporary inactivation of fimbria-fornix with lidocaine 4% promoted an anxiolytic-like effect per se, suggesting a tonic control of this pathway on the modulation of anxiety-related behaviors." | 3.76 | Short- and long-term anxiogenic effects induced by a single injection of subconvulsant doses of pilocarpine in rats: investigation of the putative role of hippocampal pathways. ( Canteras, NS; De Lima, TC; Duarte, FS; Duzzioni, M; Gavioli, EC; Hoeller, AA, 2010) |
| "This study investigated putative correlations among behavioral changes and: (1) neuronal loss, (2) hippocampal mossy fiber sprouting, and (3) reactive astrogliosis in adult rats submitted to early-life LiCl-pilocarpine-induced status epilepticus (SE)." | 3.74 | Effects of early-life LiCl-pilocarpine-induced status epilepticus on memory and anxiety in adult rats are associated with mossy fiber sprouting and elevated CSF S100B protein. ( da Silva, MC; de Oliveira, DL; e Souza, TM; Fischer, A; Gonçalves, CA; Jorge, RS; Leite, M; Quillfeldt, JA; Souza, DO; Wofchuk, S, 2008) |
| ") also potentiates oxotremorine-induced tremors in mice, in a dose-dependent manner, and this effect was completely prevented by atropine." | 3.71 | Evidence for the involvement of the muscarinic cholinergic system in the central actions of pentoxifylline. ( Cunha, GM; Farias, PA; Viana, GS, 2002) |
| "The pilocarpine model has been recognized as an animal model of TLE." | 1.43 | Time course evaluation of behavioral impairments in the pilocarpine model of epilepsy. ( Costa, AP; de Mello, N; Farina, M; Gonçalves, FM; Leal, RB; Lopes, MW; Lopes, SC; Prediger, RD; Santos, DB; Walz, R, 2016) |
| "Animals exposed to seizures in utero showed impaired social behavior with no signs of anxiety-like behavior." | 1.38 | Social behavior impairment in offspring exposed to maternal seizures in utero. ( Amado, D; Cysneiros, RM; Novaes, GF; Scorza, FA, 2012) |
| "Ketamine post-SE onset treatment prevented neuronal death in all regions assessed." | 1.38 | Ketamine reduces neuronal degeneration and anxiety levels when administered during early life-induced status epilepticus in rats. ( Córdova, SD; de Oliveira, DL; Loss, CM, 2012) |
| " In order to ensure the occurrence of status epilepticus (SE) and decrease mortality, individual dosing of pilocarpine was performed by ramping up the dose until onset of SE." | 1.34 | Behavioral alterations in the pilocarpine model of temporal lobe epilepsy in mice. ( Gröticke, I; Hoffmann, K; Löscher, W, 2007) |
| "Cycloheximide-treated animals differed from Pilo animals in the extent of hilar loss and supragranular mossy fiber sprouting as well as tissue shrinkage in the dorsal hippocampus." | 1.33 | Behavioral changes resulting from the administration of cycloheximide in the pilocarpine model of epilepsy. ( Blanco, MM; Dos Santos, JG; Longo, BM; Mello, LE; Menezes de Oliveira, MG, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (20.00) | 29.6817 |
| 2010's | 20 (66.67) | 24.3611 |
| 2020's | 4 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Pale, S | 1 |
| Neteydji, S | 1 |
| Taiwe, GS | 1 |
| Kouemou Emegam, N | 1 |
| Bum, EN | 1 |
| Hong, S | 1 |
| Xin, Y | 1 |
| JiaWen, W | 1 |
| ShuQin, Z | 1 |
| GuiLian, Z | 1 |
| HaiQin, W | 1 |
| Zhen, G | 1 |
| HongWei, R | 1 |
| YongNan, L | 1 |
| Pacheco, ALD | 1 |
| de Melo, IS | 1 |
| de Souza, FMA | 1 |
| Nicácio, DCSP | 1 |
| Freitas-Santos, J | 1 |
| Oliveira Dos Santos, YM | 1 |
| Costa, MA | 1 |
| Cavalcante, CMB | 1 |
| Gomes Dos Santos Neto, J | 1 |
| Gitaí, DLG | 1 |
| Sabino-Silva, R | 1 |
| Torres de Miranda, C | 1 |
| Borbely, AU | 1 |
| Duzzioni, M | 4 |
| Shetty, AK | 1 |
| de Castro, OW | 1 |
| Lovisari, F | 1 |
| Guarino, A | 1 |
| Soukupova, M | 1 |
| Falcicchia, C | 1 |
| Ingusci, S | 1 |
| Marino, P | 1 |
| Thomas, M | 1 |
| Sieg, F | 1 |
| Simonato, M | 1 |
| Mazumder, AG | 1 |
| Sharma, P | 1 |
| Patial, V | 1 |
| Singh, D | 1 |
| da Silva Chaves, SN | 1 |
| Felício, GR | 1 |
| Costa, BPD | 1 |
| de Oliveira, WEA | 1 |
| Lima-Maximino, MG | 1 |
| Siqueira Silva, DH | 1 |
| Maximino, C | 1 |
| Zhu, X | 1 |
| Yao, Y | 1 |
| Li, X | 1 |
| Dong, J | 1 |
| Zhang, A | 1 |
| Smolensky, IV | 1 |
| Zubareva, OE | 1 |
| Kalemenev, SV | 1 |
| Lavrentyeva, VV | 1 |
| Dyomina, AV | 1 |
| Karepanov, AA | 1 |
| Zaitsev, AV | 1 |
| Hoeller, AA | 4 |
| Duarte, FS | 3 |
| Leme, LR | 1 |
| Costa, AP | 3 |
| Santos, EC | 1 |
| de Pieri, CH | 1 |
| dos Santos, AA | 1 |
| Naime, AA | 1 |
| Farina, M | 2 |
| de Lima, TC | 4 |
| Krishnakumar, A | 1 |
| Anju, TR | 1 |
| Abraham, PM | 1 |
| Paulose, CS | 1 |
| Kogan, JH | 1 |
| Gross, AK | 1 |
| Featherstone, RE | 1 |
| Shin, R | 1 |
| Chen, Q | 1 |
| Heusner, CL | 1 |
| Adachi, M | 1 |
| Lin, A | 1 |
| Walton, NM | 1 |
| Miyoshi, S | 1 |
| Miyake, S | 1 |
| Tajinda, K | 1 |
| Ito, H | 1 |
| Siegel, SJ | 1 |
| Matsumoto, M | 1 |
| Lopes, MW | 1 |
| Lopes, SC | 1 |
| Santos, DB | 1 |
| Gonçalves, FM | 1 |
| de Mello, N | 1 |
| Prediger, RD | 1 |
| Walz, R | 2 |
| Leal, RB | 1 |
| Bicca, MA | 1 |
| Matheus, FC | 1 |
| Lach, G | 1 |
| Spiga, F | 1 |
| Lightman, SL | 1 |
| Collingridge, GL | 1 |
| Bortolotto, ZA | 1 |
| Small, KM | 1 |
| Nunes, E | 1 |
| Hughley, S | 1 |
| Addy, NA | 1 |
| Otsuka, S | 1 |
| Ohkido, T | 1 |
| Itakura, M | 1 |
| Watanabe, S | 1 |
| Yamamori, S | 1 |
| Iida, Y | 1 |
| Saito, M | 1 |
| Miyaoka, H | 1 |
| Takahashi, M | 1 |
| Yang, H | 1 |
| Jung, S | 1 |
| Seo, J | 1 |
| Khalid, A | 1 |
| Yoo, JS | 1 |
| Park, J | 1 |
| Kim, S | 1 |
| Moon, J | 1 |
| Lee, ST | 1 |
| Jung, KH | 1 |
| Chu, K | 1 |
| Lee, SK | 1 |
| Jeon, D | 1 |
| Bogovyk, R | 1 |
| Lunko, O | 1 |
| Fedoriuk, M | 1 |
| Isaev, D | 1 |
| Krishtal, O | 1 |
| Holmes, GL | 1 |
| Isaeva, E | 1 |
| Gulec, G | 1 |
| Isbil-Buyukcoskun, N | 1 |
| Kahveci, N | 1 |
| Lima, DC | 1 |
| Vale, TG | 1 |
| Arganãraz, GA | 1 |
| Varella, PP | 1 |
| Frussa-Filho, R | 1 |
| Cavalheiro, EA | 2 |
| Naffah-Mazzacoratti, Mda G | 1 |
| Amado, D | 2 |
| Gavioli, EC | 2 |
| Canteras, NS | 1 |
| Inostroza, M | 1 |
| Cid, E | 1 |
| Brotons-Mas, J | 1 |
| Gal, B | 1 |
| Aivar, P | 1 |
| Uzcategui, YG | 1 |
| Sandi, C | 1 |
| Menendez de la Prida, L | 1 |
| Novaes, GF | 1 |
| Scorza, FA | 1 |
| Cysneiros, RM | 1 |
| Loss, CM | 1 |
| Córdova, SD | 1 |
| de Oliveira, DL | 2 |
| Silva, NM | 1 |
| Ern, AL | 1 |
| Piermartiri, TC | 1 |
| Tasca, CI | 1 |
| Lemos, T | 1 |
| Carobrez, AP | 1 |
| Detour, J | 1 |
| Schroeder, H | 1 |
| Desor, D | 1 |
| Nehlig, A | 1 |
| Dos Santos, JG | 1 |
| Longo, BM | 1 |
| Blanco, MM | 1 |
| Menezes de Oliveira, MG | 1 |
| Mello, LE | 1 |
| Gröticke, I | 1 |
| Hoffmann, K | 1 |
| Löscher, W | 1 |
| Fischer, A | 1 |
| Jorge, RS | 1 |
| da Silva, MC | 1 |
| Leite, M | 1 |
| Gonçalves, CA | 1 |
| Quillfeldt, JA | 1 |
| Souza, DO | 1 |
| e Souza, TM | 1 |
| Wofchuk, S | 1 |
| dos Santos, NF | 1 |
| Arida, RM | 1 |
| Filho, EM | 1 |
| Priel, MR | 1 |
| Cunha, GM | 1 |
| Farias, PA | 1 |
| Viana, GS | 1 |
30 other studies available for pilocarpine and Anxiety
| Article | Year |
|---|---|
Anticonvulsant effects of Cymbopogon giganteus extracts with possible effects on fully kindled seizures and anxiety in experimental rodent model of mesio-temporal epilepsy induced by pilocarpine.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Cymbopogon; Disease Models, Animal; Dose-Res | 2022 |
The P2X7 receptor in activated microglia promotes depression- and anxiety-like behaviors in lithium -pilocarpine induced epileptic rats.
Topics: Animals; Anxiety; Depression; Lithium; Male; Microglia; Pilocarpine; Purinergic P2X Receptor Antagon | 2020 |
Maternal crack cocaine use in rats leads to depressive- and anxiety-like behavior, memory impairment, and increased seizure susceptibility in the offspring.
Topics: Animals; Anxiety; Cocaine-Related Disorders; Crack Cocaine; Epilepsy; Female; Male; Memory Disorders | 2021 |
Anti-epileptogenic effect of NRP2945 in the pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Anxiety; Behavior, Animal; Convulsants; Epilepsy, Temporal Lobe; Male; Neu | 2021 |
Ginkgo biloba L. attenuates spontaneous recurrent seizures and associated neurological conditions in lithium-pilocarpine rat model of temporal lobe epilepsy through inhibition of mammalian target of rapamycin pathway hyperactivation.
Topics: Aggression; Animals; Anticonvulsants; Anxiety; Behavior, Animal; Brain; Depression; Epilepsy, Tempor | 2017 |
Behavioral and biochemical effects of ethanol withdrawal in zebrafish.
Topics: Animals; Anxiety; Brain; Catalase; Darkness; Ethanol; Meta-Analysis as Topic; Models, Biological; Pi | 2018 |
Alteration of GABAergic signaling is associated with anxiety-like behavior in temporal lobe epilepsy mice.
Topics: Animals; Anxiety; Blotting, Western; Disease Models, Animal; Epilepsy, Temporal Lobe; GABAergic Neur | 2019 |
Impairments in cognitive functions and emotional and social behaviors in a rat lithium-pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Anxiety; Behavior, Animal; Cognition; Emotions; Epilepsy; Epilepsy, Temporal Lobe; Explorat | 2019 |
GABA-A receptor modulators alter emotionality and hippocampal theta rhythm in an animal model of long-lasting anxiety.
Topics: Animals; Anxiety; Diazepam; Disease Models, Animal; Electroencephalography; Emotions; GABA Antagonis | 2013 |
Alteration in 5-HT₂C, NMDA receptor and IP3 in cerebral cortex of epileptic rats: restorative role of Bacopa monnieri.
Topics: Animals; Anxiety; Bacopa; Behavior, Animal; Cerebral Cortex; Convulsants; Epilepsy; Excitatory Amino | 2015 |
Mouse Model of Chromosome 15q13.3 Microdeletion Syndrome Demonstrates Features Related to Autism Spectrum Disorder.
Topics: Animals; Anxiety; Association Learning; Autism Spectrum Disorder; Brain; Chromosome Deletion; Chromo | 2015 |
Time course evaluation of behavioral impairments in the pilocarpine model of epilepsy.
Topics: Animals; Anxiety; Disease Models, Animal; Epilepsy, Temporal Lobe; Exploratory Behavior; Male; Maze | 2016 |
The Role of Hippocampal NMDA Receptors in Long-Term Emotional Responses following Muscarinic Receptor Activation.
Topics: Animals; Anxiety; Behavior, Animal; Blotting, Western; Emotions; Hippocampus; Male; Maze Learning; P | 2016 |
Ventral tegmental area muscarinic receptors modulate depression and anxiety-related behaviors in rats.
Topics: Animals; Anxiety; Behavior, Animal; Cholinesterase Inhibitors; Depression; Food Preferences; Male; M | 2016 |
Dual mechanisms of rapid expression of anxiety-related behavior in pilocarpine-treated epileptic mice.
Topics: Actins; Analysis of Variance; Animals; Anxiety; Behavior Observation Techniques; Brain-Derived Neuro | 2016 |
Altered behavior and neural activity in conspecific cagemates co-housed with mouse models of brain disorders.
Topics: Analysis of Variance; Animals; Anxiety; Brain; Depression; Electroshock; Epilepsy, Temporal Lobe; Ex | 2016 |
Effects of protease-activated receptor 1 inhibition on anxiety and fear following status epilepticus.
Topics: Animals; Anxiety; Epilepsy, Temporal Lobe; Fear; Male; Pilocarpine; Pyrroles; Quinazolines; Rats; Ra | 2017 |
Effects of centrally-injected glucagon-like peptide-1 on pilocarpine-induced seizures, anxiety and locomotor and exploratory activity in rat.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Antidiuretic Hormone Receptor Antagonists; Anxiety; E | 2010 |
Behavioral evaluation of adult rats exposed in utero to maternal epileptic seizures.
Topics: Animals; Anxiety; Behavior, Animal; Depression; Epilepsy; Female; Male; Motor Activity; Pilocarpine; | 2010 |
Short- and long-term anxiogenic effects induced by a single injection of subconvulsant doses of pilocarpine in rats: investigation of the putative role of hippocampal pathways.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Anxiety; Behavior, Animal; Dose-Response Relation | 2010 |
Hippocampal-dependent spatial memory in the water maze is preserved in an experimental model of temporal lobe epilepsy in rats.
Topics: Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Electrophysiology; Epilepsy, Temporal Lo | 2011 |
Social behavior impairment in offspring exposed to maternal seizures in utero.
Topics: Animals; Anxiety; Convulsants; Epilepsy, Tonic-Clonic; Female; Male; Pilocarpine; Pregnancy; Pregnan | 2012 |
Ketamine reduces neuronal degeneration and anxiety levels when administered during early life-induced status epilepticus in rats.
Topics: Animals; Anxiety; Brain; Convulsants; Ketamine; Male; Nerve Degeneration; Neuroprotective Agents; Pi | 2012 |
Anxiogenic-like profile of Wistar adult rats based on the pilocarpine model: an animal model for trait anxiety?
Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Cell Death; Disease Models, Animal; Dose-Res | 2013 |
A 5-month period of epilepsy impairs spatial memory, decreases anxiety, but spares object recognition in the lithium-pilocarpine model in adult rats.
Topics: Animals; Anxiety; Behavior, Animal; Cell Count; Disease Models, Animal; Entorhinal Cortex; Epilepsy, | 2005 |
Behavioral changes resulting from the administration of cycloheximide in the pilocarpine model of epilepsy.
Topics: Acoustic Stimulation; Animals; Anxiety; Behavior, Animal; Cell Count; Conditioning, Psychological; C | 2005 |
Behavioral alterations in the pilocarpine model of temporal lobe epilepsy in mice.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleat | 2007 |
Effects of early-life LiCl-pilocarpine-induced status epilepticus on memory and anxiety in adult rats are associated with mossy fiber sprouting and elevated CSF S100B protein.
Topics: Age Factors; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Fear; Hippocampus; Lithium Chlori | 2008 |
Epileptogenesis in immature rats following recurrent status epilepticus.
Topics: Age Factors; Animals; Anxiety; Avoidance Learning; Brain; Electroencephalography; Exploratory Behavi | 2000 |
Evidence for the involvement of the muscarinic cholinergic system in the central actions of pentoxifylline.
Topics: Acetylcholinesterase; Animals; Anxiety; Avoidance Learning; Hippocampus; Learning Disabilities; Male | 2002 |