pilocarpine has been researched along with Angiogenesis, Pathologic in 4 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We induced status epilepticus (SE) with pilocarpine in adult rats, and investigated endothelial cell proliferation (BrdU and rat endothelial cell antigen-1 (RECA-1) double-labeling), vessel length (unbiased stereology), thrombocyte aggregation (thrombocyte immunostaining), neurodegeneration (Nissl staining), neurogenesis (doublecortin (DCX) immunohistochemistry), and mossy fiber sprouting (Timm staining) in the hippocampus at different time points post-SE." | 7.76 | Vascular changes in epilepsy: functional consequences and association with network plasticity in pilocarpine-induced experimental epilepsy. ( Gröhn, O; Hayward, N; Ndode-Ekane, XE; Pitkänen, A, 2010) |
| " We induced status epilepticus (SE) with pilocarpine in adult rats, and investigated endothelial cell proliferation (BrdU and rat endothelial cell antigen-1 (RECA-1) double-labeling), vessel length (unbiased stereology), thrombocyte aggregation (thrombocyte immunostaining), neurodegeneration (Nissl staining), neurogenesis (doublecortin (DCX) immunohistochemistry), and mossy fiber sprouting (Timm staining) in the hippocampus at different time points post-SE." | 3.76 | Vascular changes in epilepsy: functional consequences and association with network plasticity in pilocarpine-induced experimental epilepsy. ( Gröhn, O; Hayward, N; Ndode-Ekane, XE; Pitkänen, A, 2010) |
| " Inflammation, angiogenesis and BBB permeability were studied in postnatal day (PN)9 and PN21 rats, 1 week and 4 months after pilocarpine-induced status epilepticus." | 3.75 | Age-dependent vascular changes induced by status epilepticus in rat forebrain: implications for epileptogenesis. ( Balosso, S; Gagliardi, B; Lerner-Natoli, M; Marcon, J; Maroso, M; Morin, M; Noé, F; Ravizza, T; Vezzani, A, 2009) |
| "Sham-treated pilocarpine rats but not sunitinib-treated pilocarpine rats had significantly smaller hippocampi." | 1.43 | Does angiogenesis play a role in the establishment of mesial temporal lobe epilepsy? ( Avoli, M; Benini, R; Khoja, Z; Roth, R; Wintermark, P, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benini, R | 1 |
| Roth, R | 1 |
| Khoja, Z | 1 |
| Avoli, M | 1 |
| Wintermark, P | 1 |
| Marcon, J | 1 |
| Gagliardi, B | 1 |
| Balosso, S | 1 |
| Maroso, M | 1 |
| Noé, F | 1 |
| Morin, M | 1 |
| Lerner-Natoli, M | 1 |
| Vezzani, A | 1 |
| Ravizza, T | 1 |
| Ndode-Ekane, XE | 1 |
| Hayward, N | 1 |
| Gröhn, O | 1 |
| Pitkänen, A | 1 |
| Mourad, JJ | 1 |
| des Guetz, G | 1 |
| Debbabi, H | 1 |
| Levy, BI | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Exploratory Study. Endothelial Function and Vascular Biomarkers: Predictive Indicators of the Progression From Gestational Hypertension to Preeclampsia?[NCT04520048] | 110 participants (Anticipated) | Interventional | 2023-08-24 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for pilocarpine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Does angiogenesis play a role in the establishment of mesial temporal lobe epilepsy?
Topics: Angiogenesis Inhibitors; Animals; Cell Count; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippo | 2016 |
Age-dependent vascular changes induced by status epilepticus in rat forebrain: implications for epileptogenesis.
Topics: Aging; Animals; Astrocytes; Blood-Brain Barrier; Encephalitis; Fluorescein-5-isothiocyanate; Genes, | 2009 |
Vascular changes in epilepsy: functional consequences and association with network plasticity in pilocarpine-induced experimental epilepsy.
Topics: Animals; Antigens; Blood-Brain Barrier; Capillaries; Cell Proliferation; Convulsants; Disease Models | 2010 |
Blood pressure rise following angiogenesis inhibition by bevacizumab. A crucial role for microcirculation.
Topics: Adenocarcinoma; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Human | 2008 |