pilocarpine has been researched along with Amyotrophic Lateral Sclerosis in 2 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kong, Q | 1 |
| Chang, LC | 1 |
| Takahashi, K | 1 |
| Liu, Q | 1 |
| Schulte, DA | 1 |
| Lai, L | 1 |
| Ibabao, B | 1 |
| Lin, Y | 1 |
| Stouffer, N | 1 |
| Das Mukhopadhyay, C | 1 |
| Xing, X | 1 |
| Seyb, KI | 1 |
| Cuny, GD | 1 |
| Glicksman, MA | 1 |
| Lin, CL | 1 |
| Charchaflie, RJ | 1 |
| Bustos Fernandez, L | 1 |
| Perec, CJ | 1 |
| Gonzalez, E | 1 |
| Marzi, A | 1 |
2 other studies available for pilocarpine and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection.
Topics: Amyotrophic Lateral Sclerosis; Animals; Anterior Horn Cells; Astrocytes; Cell Line; Coculture Techni | 2014 |
Functional studies of the parotid and pancreas glands in amyotrophic lateral sclerosis.
Topics: Adult; Aged; Amylases; Amyotrophic Lateral Sclerosis; Bicarbonates; Cholecystokinin; Citrates; Femal | 1974 |