pilocarpine has been researched along with Amnesia in 3 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amnesia for a multiple trial appetitive spatial dicrimination habit induced by the protein synthesis inhibitor cycloheximide (CXM) was reversed by peripheral injections of both alpha (clonidine) and beta (isoproterenol) norepinephrine receptor stimulators." | 7.65 | Reversal of cycloheximide-induced amnesia by adrenergic receptor stimulation. ( Botwinick, CY; Freedman, LS; Gutwein, BM; Quartermain, D, 1977) |
| "Amnesia for a multiple trial appetitive spatial dicrimination habit induced by the protein synthesis inhibitor cycloheximide (CXM) was reversed by peripheral injections of both alpha (clonidine) and beta (isoproterenol) norepinephrine receptor stimulators." | 3.65 | Reversal of cycloheximide-induced amnesia by adrenergic receptor stimulation. ( Botwinick, CY; Freedman, LS; Gutwein, BM; Quartermain, D, 1977) |
| "Pilocarpine treatment significantly restored the scopolamine-induced impaired recognition memory and downregulated hippocampal IEGs expression and phosphorylation of ERK1/2 (extracellular signal-regulated kinase 1/2) and CREB (cAMP response element-binding protein)." | 1.72 | Muscarinic Acetylcholine Receptors-Mediated Activation of PKC Restores the Hippocampal Immediate Early Gene Expression and CREB Phosphorylation in Scopolamine-Induced Amnesic Mice. ( Barman, B; Kushwaha, A; Thakur, MK, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Barman, B | 1 |
| Kushwaha, A | 1 |
| Thakur, MK | 1 |
| Quartermain, D | 1 |
| Freedman, LS | 1 |
| Botwinick, CY | 1 |
| Gutwein, BM | 1 |
| Riekkinen, P | 2 |
| Sirviö, J | 1 |
| Ekonsalo, T | 1 |
3 other studies available for pilocarpine and Amnesia
| Article | Year |
|---|---|
Muscarinic Acetylcholine Receptors-Mediated Activation of PKC Restores the Hippocampal Immediate Early Gene Expression and CREB Phosphorylation in Scopolamine-Induced Amnesic Mice.
Topics: Amnesia; Animals; Cholinergic Agents; Cyclic AMP Response Element-Binding Protein; Genes, Immediate- | 2022 |
Reversal of cycloheximide-induced amnesia by adrenergic receptor stimulation.
Topics: Amnesia; Animals; Brain Chemistry; Catecholamines; Clonidine; Cycloheximide; Drug Interactions; Huma | 1977 |
Effects of noradrenergic DSP4 lesion on the effectiveness of pilocarpine in reversing scopolamine-induced amnesia.
Topics: Amnesia; Animals; Benzylamines; Male; Norepinephrine; Pilocarpine; Rats; Rats, Inbred Strains; Scopo | 1992 |