pilocarpine has been researched along with Aggression in 33 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, in this study, we observed a significant increase in neuroinflammation and in the proliferation and survival of newborn granular cells in the hippocampus of pilocarpine-induced status epilepticus (SE) mice." | 7.96 | Seizure-induced neuroinflammation contributes to ectopic neurogenesis and aggressive behavior in pilocarpine-induced status epilepticus mice. ( Gan, G; Ge, Q; Liu, X; Niu, D; Yang, J; Yao, H; Yao, Y; Zhang, A; Zhang, C; Zhu, X, 2020) |
| "Aggressive behaviors (numbers of bites/hour) within groups (ns = 8) of normal rats and rats in which seizures had been induced by a single systemic injection of lithium/pilocarpine were observed for 11 successive, 1-hr, periods." | 7.69 | Association between intermale social aggression and cellular density within the central amygdaloid nucleus in rats with lithium/pilocarpine-induced seizures. ( Desjardins, D; Persinger, MA, 1995) |
| "Several domains of behavior were measured in rats (n = 465) 10 days to 100 days after induction of limbic seizures by a single subcutaneous injection of lithium and pilocarpine." | 7.68 | Behaviors of rats with insidious, multifocal brain damage induced by seizures following single peripheral injections of lithium and pilocarpine. ( Bureau, YR; Falter, H; Kostakos, M; Peredery, O; Persinger, MA, 1993) |
| "Both morphine and the neuroleptics, haloperidol and oxyperomide, dose-dependently reduce the aggression in rats produced by 20 mg/kg of apomorphine, a dopamine receptor stimulant." | 7.65 | Blockade of apomorphine-induced aggression by morphine or neuroleptics: differential alteration by antimuscarinics and naloxone. ( Gianutsos, G; Lal, H, 1976) |
| "Spontaneous recurrent seizures were monitored with Racine's seizure severity scale." | 5.32 | Human neural stem cell transplantation reduces spontaneous recurrent seizures following pilocarpine-induced status epilepticus in adult rats. ( Chu, K; Jeon, D; Jeong, SW; Jung, KH; Kim, J; Kim, M; Kim, SU; Lee, SK; Lee, ST; Roh, JK; Shin, HS, 2004) |
| "Untreated lithium/pilocarpine SE induced a large increase in aggressive behavior, which involved all aspects of aggression in the resident-intruder paradigm when tested 3 months after SE." | 4.31 | Interictal aggression in rats with chronic seizures after an early life episode of status epilepticus. ( Baldwin, RA; Niquet, J; Suchomelova, L; Thompson, KW; Wasterlain, CG, 2023) |
| " Here, in this study, we observed a significant increase in neuroinflammation and in the proliferation and survival of newborn granular cells in the hippocampus of pilocarpine-induced status epilepticus (SE) mice." | 3.96 | Seizure-induced neuroinflammation contributes to ectopic neurogenesis and aggressive behavior in pilocarpine-induced status epilepticus mice. ( Gan, G; Ge, Q; Liu, X; Niu, D; Yang, J; Yao, H; Yao, Y; Zhang, A; Zhang, C; Zhu, X, 2020) |
| "The results of present study concluded that GBbf treatment suppressed lithium-pilocarpine induced spontaneous recurrent seizures severity and incidence with improved cognitive functions, reduced anxiety-like behavior and aggression." | 3.85 | Ginkgo biloba L. attenuates spontaneous recurrent seizures and associated neurological conditions in lithium-pilocarpine rat model of temporal lobe epilepsy through inhibition of mammalian target of rapamycin pathway hyperactivation. ( Mazumder, AG; Patial, V; Sharma, P; Singh, D, 2017) |
| "The present study examined whether status epilepticus (SE) induced by LiCl-pilocarpine in immature rats (postnatal day [P]12) interferes with normal development; leads to progressive epileptogenesis, or cognitive decline and to pathology similar to that seen in human temporal lobe epilepsy." | 3.79 | Are morphologic and functional consequences of status epilepticus in infant rats progressive? ( Kubová, H; Mareš, P, 2013) |
| " Following pilocarpine-induced status epilepticus (SE), experimental animals not only developed spontaneous recurrent seizures, but also exhibited significantly elevated levels of aggressive behavior." | 3.78 | Rapamycin attenuates aggressive behavior in a rat model of pilocarpine-induced epilepsy. ( Huang, X; Huang, Y; McMahon, J, 2012) |
| "Aggressive behaviors (numbers of bites/hour) within groups (ns = 8) of normal rats and rats in which seizures had been induced by a single systemic injection of lithium/pilocarpine were observed for 11 successive, 1-hr, periods." | 3.69 | Association between intermale social aggression and cellular density within the central amygdaloid nucleus in rats with lithium/pilocarpine-induced seizures. ( Desjardins, D; Persinger, MA, 1995) |
| "Several domains of behavior were measured in rats (n = 465) 10 days to 100 days after induction of limbic seizures by a single subcutaneous injection of lithium and pilocarpine." | 3.68 | Behaviors of rats with insidious, multifocal brain damage induced by seizures following single peripheral injections of lithium and pilocarpine. ( Bureau, YR; Falter, H; Kostakos, M; Peredery, O; Persinger, MA, 1993) |
| "Seizures induced by pilocarpine (PILO) have proven to be a useful procedure for investigating the basic mechanisms essential for generation, spread and motor expression of seizures in rodents." | 3.68 | Spontaneous recurrent seizures in rats: an experimental model of partial epilepsy. ( Bortolotto, ZA; Cavalheiro, EA; Leite, JP, 1990) |
| " Despite its lesser tendency to induce aggression in humans, Oxazepam is as potent as Chlordiazepoxide for inducing killing by rats." | 3.67 | Oxazepam induced mouse killing by rats. ( Lamon, S; Leaf, RC; Wnek, DJ, 1984) |
| "Both morphine and the neuroleptics, haloperidol and oxyperomide, dose-dependently reduce the aggression in rats produced by 20 mg/kg of apomorphine, a dopamine receptor stimulant." | 3.65 | Blockade of apomorphine-induced aggression by morphine or neuroleptics: differential alteration by antimuscarinics and naloxone. ( Gianutsos, G; Lal, H, 1976) |
| "Spontaneous recurrent seizures were monitored with Racine's seizure severity scale." | 1.32 | Human neural stem cell transplantation reduces spontaneous recurrent seizures following pilocarpine-induced status epilepticus in adult rats. ( Chu, K; Jeon, D; Jeong, SW; Jung, KH; Kim, J; Kim, M; Kim, SU; Lee, SK; Lee, ST; Roh, JK; Shin, HS, 2004) |
| "Paradoxical sleep deprivation (PSD) induces changes in behaviors induced by dopaminergic and cholinergic agonists, including increased aggressive behavior and stereotypy, decreased number of yawns, and shedding of bloody tears in male rats." | 1.29 | Paradoxical sleep deprivation in female rats alters drug-induced behaviors. ( Hipólide, DC; Tufik, S, 1995) |
| "Diazepam was equally effective, and several times more potent than chlordiazepoxide." | 1.25 | Chlordiazepoxide and diazepam induced mouse killing by rats. ( Corcia, RM; Gay, PE; Lamon, S; Leaf, RC; Wnek, DJ, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (57.58) | 18.7374 |
| 1990's | 5 (15.15) | 18.2507 |
| 2000's | 4 (12.12) | 29.6817 |
| 2010's | 3 (9.09) | 24.3611 |
| 2020's | 2 (6.06) | 2.80 |
| Authors | Studies |
|---|---|
| Suchomelova, L | 1 |
| Thompson, KW | 1 |
| Baldwin, RA | 1 |
| Niquet, J | 1 |
| Wasterlain, CG | 1 |
| Zhu, X | 1 |
| Yao, Y | 1 |
| Yang, J | 1 |
| Ge, Q | 1 |
| Niu, D | 1 |
| Liu, X | 1 |
| Zhang, C | 1 |
| Gan, G | 1 |
| Zhang, A | 1 |
| Yao, H | 1 |
| Mazumder, AG | 1 |
| Sharma, P | 1 |
| Patial, V | 1 |
| Singh, D | 1 |
| Ismail, N | 1 |
| Christine, S | 1 |
| Robinson, GE | 1 |
| Fahrbach, SE | 1 |
| Huang, X | 1 |
| McMahon, J | 1 |
| Huang, Y | 1 |
| Kubová, H | 1 |
| Mareš, P | 1 |
| Chu, K | 1 |
| Kim, M | 1 |
| Jung, KH | 1 |
| Jeon, D | 1 |
| Lee, ST | 1 |
| Kim, J | 1 |
| Jeong, SW | 1 |
| Kim, SU | 1 |
| Lee, SK | 1 |
| Shin, HS | 1 |
| Roh, JK | 1 |
| Kaneko, T | 1 |
| Kitahara, A | 1 |
| Ozaki, S | 1 |
| Takizawa, K | 1 |
| Yamatsu, K | 1 |
| Pedersen, EB | 1 |
| Poulsen, K | 1 |
| Leaf, RC | 5 |
| Wnek, DJ | 4 |
| Lamon, S | 2 |
| Milart, P | 1 |
| Turski, W | 1 |
| Czuczwar, S | 1 |
| Kleinrok, Z | 1 |
| Hipólide, DC | 1 |
| Tufik, S | 1 |
| Persinger, MA | 3 |
| Bureau, YR | 1 |
| Kostakos, M | 1 |
| Peredery, O | 1 |
| Falter, H | 1 |
| Desjardins, D | 1 |
| St Pierre, L | 1 |
| Aleksidze, NG | 1 |
| Goguadze, RP | 1 |
| Mikiashvili, NA | 1 |
| Chipashvili, MD | 1 |
| Hamani, C | 1 |
| Mello, LE | 1 |
| Roliński, Z | 1 |
| Barr, GA | 1 |
| Bridger, WH | 1 |
| Gibbons, JL | 1 |
| Gianutsos, G | 2 |
| Lal, H | 2 |
| Miczek, KA | 2 |
| Miley, WM | 1 |
| Posner, I | 1 |
| Bierbrauer, B | 1 |
| Gay, PE | 2 |
| Cole, SO | 1 |
| Corcia, RM | 1 |
| Leite, JP | 1 |
| Bortolotto, ZA | 1 |
| Cavalheiro, EA | 1 |
| Wilson, LI | 1 |
| Bierley, RA | 1 |
| Beatty, WW | 1 |
| Vogel, JR | 1 |
| Pino, N | 2 |
| Chiofalo, L | 2 |
| Ferrari, E | 1 |
| Consolo, F | 1 |
1 review available for pilocarpine and Aggression
| Article | Year |
|---|---|
Neuropharmacological regulation of mouse killing by rats.
Topics: Acetylcholine; Aggression; Animals; Behavior, Animal; Catecholamines; Fenclonine; Histamine; Humans; | 1976 |
32 other studies available for pilocarpine and Aggression
| Article | Year |
|---|---|
Interictal aggression in rats with chronic seizures after an early life episode of status epilepticus.
Topics: Aggression; Animals; Epilepsy; Lithium; Male; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epil | 2023 |
Seizure-induced neuroinflammation contributes to ectopic neurogenesis and aggressive behavior in pilocarpine-induced status epilepticus mice.
Topics: Aggression; Animals; Cell Proliferation; Hippocampus; Inflammation; Male; Mice; Mice, Inbred C57BL; | 2020 |
Ginkgo biloba L. attenuates spontaneous recurrent seizures and associated neurological conditions in lithium-pilocarpine rat model of temporal lobe epilepsy through inhibition of mammalian target of rapamycin pathway hyperactivation.
Topics: Aggression; Animals; Anticonvulsants; Anxiety; Behavior, Animal; Brain; Depression; Epilepsy, Tempor | 2017 |
Pilocarpine improves recognition of nestmates in young honey bees.
Topics: Aggression; Animals; Bees; Behavior, Animal; Motor Activity; Muscarinic Agonists; Muscarinic Antagon | 2008 |
Rapamycin attenuates aggressive behavior in a rat model of pilocarpine-induced epilepsy.
Topics: Aggression; Animals; Behavior, Animal; Disease Models, Animal; Immunosuppressive Agents; Physical St | 2012 |
Are morphologic and functional consequences of status epilepticus in infant rats progressive?
Topics: Aggression; Aging; Animals; Animals, Newborn; Antimanic Agents; Atrophy; Behavior, Animal; Brain; Ce | 2013 |
Human neural stem cell transplantation reduces spontaneous recurrent seizures following pilocarpine-induced status epilepticus in adult rats.
Topics: Aggression; Animals; Animals, Newborn; Behavior, Animal; Cell Count; Cell Death; Cells, Cultured; El | 2004 |
Effects of azelastine hydrochloride, a novel anti-allergic drug, on the central nervous system.
Topics: Aggression; Animals; Anticonvulsants; Avoidance Learning; Body Temperature; Central Nervous System; | 1981 |
Aggression-provoked huge release of submaxillary mouse renin to saliva.
Topics: Aggression; Animals; Humans; Male; Mice; Phenylephrine; Pilocarpine; Renin; Saliva; Salivation; Subm | 1983 |
Oxazepam induced mouse killing by rats.
Topics: Aggression; Animals; Chlordiazepoxide; Chlorpromazine; Dose-Response Relationship, Drug; Humans; Mal | 1984 |
Effects of atropine, pilocarpine and morphine on footshock-induced aggressive behaviour in rats after lesion of hippocampal pyramidal cells with kainic acid.
Topics: Aggression; Animals; Atropine; Drug Interactions; Electroshock; Hippocampus; Humans; Kainic Acid; Ma | 1982 |
Paradoxical sleep deprivation in female rats alters drug-induced behaviors.
Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Body Temperature; Female; Pilocarpine; Rats; Rat | 1995 |
Behaviors of rats with insidious, multifocal brain damage induced by seizures following single peripheral injections of lithium and pilocarpine.
Topics: Acetylcholine; Aggression; Animals; Association Learning; Avoidance Learning; Brain; Brain Damage, C | 1993 |
Association between intermale social aggression and cellular density within the central amygdaloid nucleus in rats with lithium/pilocarpine-induced seizures.
Topics: Aggression; Amygdala; Animals; Behavior, Animal; Lithium; Male; Muscarinic Agonists; Neuroglia; Neur | 1995 |
Geophysical variables and behavior: LXXXIV. Quantitative increases in group aggression in male epileptic rats during increases in geomagnetic activity.
Topics: Aggression; Animals; Behavior, Animal; Epilepsy; Geography; Limbic System; Lithium; Magnetics; Male; | 1998 |
Metabolism of biogenic amines in rat brain during pilocarpine-induced aggression.
Topics: Aggression; Animals; Behavior, Animal; Biogenic Amines; Brain; Darkness; Hippocampus; Hypothalamus; | 2001 |
Spontaneous recurrent seizures and neuropathology in the chronic phase of the pilocarpine and picrotoxin model epilepsy.
Topics: Acetylcholine; Action Potentials; Aggression; Animals; Behavior, Animal; Brain; Chronic Disease; Dis | 2002 |
Interspecies aggressiveness of rats towards mice after the application of p-chlorophenylalanine.
Topics: Aggression; Animals; Atropine; Behavior, Animal; Cyproheptadine; Female; Fenclonine; Humans; Imipram | 1975 |
Modification of apomorphine induced aggression by changing central cholinergic activity in rats.
Topics: Aggression; Animals; Apomorphine; Atropine; Dexetimide; Humans; Iodides; Male; Parasympathetic Nervo | 1977 |
A behavioral analysis of aggressive behaviors induced and modulated by delta9-tetrahydrocannabinol, pilocarpine, d-amphetamine and l-dopa [proceedings].
Topics: Aggression; Animals; Behavior, Animal; Dextroamphetamine; Dominance-Subordination; Dronabinol; Human | 1977 |
Effects of combining pilocarpine, d-amphetamine, and either a free feeding schedule or cyclic food deprivation on mouse killing by rats.
Topics: Aggression; Animals; Dextroamphetamine; Drug Antagonism; Feeding Behavior; Food Deprivation; Humans; | 1978 |
Pilocarpine, food deprivation, and induction of mouse killing by cats.
Topics: Aggression; Animals; Atropine; Cats; Chlordiazepoxide; Female; Food Deprivation; Humans; Male; Mice; | 1978 |
Interactions of amygdala lesions with effects of pilocarpine and d-amphetamine on mouse killing, feeding, and drinking in rats.
Topics: Aggression; Amygdala; Animals; Behavior, Animal; Body Weight; Dextroamphetamine; Dose-Response Relat | 1976 |
Mouse-killing and motor activity: effects of chronic delta9-tetrahydrocannabinol and pilocarpine.
Topics: Aggression; Animals; Cannabis; Crowding; Dose-Response Relationship, Drug; Dronabinol; Drug Toleranc | 1976 |
Blockade of apomorphine-induced aggression by morphine or neuroleptics: differential alteration by antimuscarinics and naloxone.
Topics: Aggression; Animals; Apomorphine; Drug Interactions; Humans; Male; Morphine; Naloxone; Parasympathol | 1976 |
Chlordiazepoxide and diazepam induced mouse killing by rats.
Topics: Aggression; Amphetamine; Animals; Behavior, Animal; Chlordiazepoxide; Diazepam; Dose-Response Relati | 1975 |
Spontaneous recurrent seizures in rats: an experimental model of partial epilepsy.
Topics: Aggression; Amygdala; Animals; Behavior, Animal; Cerebral Cortex; Disease Models, Animal; Electroenc | 1990 |
Cholinergic agonists suppress play fighting in juvenile rats.
Topics: Aggression; Animals; Arecoline; Male; Parasympathomimetics; Pilocarpine; Rats; Rats, Inbred Strains | 1986 |
Initiation of mouse killing in non-killer rats by repeated pilocarpine treatment.
Topics: Aggression; Animals; Behavior, Animal; Brain Chemistry; Female; Fenclonine; Humans; Injections, Intr | 1972 |
Effects of cholinergic drugs on prey-killing by rodents.
Topics: Aggression; Animals; Appetitive Behavior; Arecoline; Atropine; Dose-Response Relationship, Drug; Hum | 1973 |
[Zootechnical considerations on the role of the parasympathetic nervous system in the aggressive behavior of capra hircus: experimental research with pilocarpine].
Topics: Aggression; Animals; Behavior, Animal; Goats; Humans; Parasympathetic Nervous System; Pilocarpine | 1968 |
[The role of the parasympathetic nervous system in the effects of aggressive behavior. Experimental research with pilocarpine in Capra hircusi].
Topics: Aggression; Animals; Behavior, Animal; Catecholamines; Goats; Hematocrit; Humans; Parasympathetic Ne | 1968 |