pilocarpine has been researched along with Adie Syndrome in 23 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Adie Syndrome: A syndrome characterized by a TONIC PUPIL that occurs in combination with decreased lower extremity reflexes. The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction. Pathologic features include degeneration of the ciliary ganglion and postganglionic parasympathetic fibers that innervate the pupillary constrictor muscle. (From Adams et al., Principles of Neurology, 6th ed, p279)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated pupillary responses to parasympathetic (pilocarpine) and sympathetic agents (tyramine, cocaine, and phenylephrine) in a 51-year-old woman with tonic pupils, loss of muscle stretch reflexes in the limbs, and hemifacial loss of sweating and flushing (Ross' syndrome)." | 3.68 | Loss of facial sweating and flushing in Holmes-Adie syndrome. ( Drummond, PD; Edis, RH, 1990) |
| "The benign syndrome of pupillotonia and absence of deep reflexes is not uncommon." | 1.38 | [Tonic pupil, pupil Adie syndrome Adie Holmes: current reassessment of terminology -- a clinical case]. ( Popescu, LA; Rusu, A; Szabo, B, 2012) |
| "A total of 61 patients with Adie's syndrome or Adie's-like denervation of the iris sphincter (from surgery, trauma, or radiation) and 10 normal subjects were studied." | 1.30 | Segmental denervation and reinnervation of the iris sphincter as shown by infrared videographic transillumination. ( Corbett, JJ; Kardon, RH; Thompson, HS, 1998) |
| "A symptomatic patient with Adie's syndrome is described as successfully managed with pilocarpine 0." | 1.27 | Adie's syndrome: a medical treatment for symptomatic patients. ( Dolan, BJ; Flach, AJ, 1984) |
| "Our study suggests those patients with Adie's Syndrome who lack stereoacuity may benefit from long term therapy with dilute pilocarpine if their stereoacuity may benefit from long term therapy with dilute pilocarpine if their stereoacuity improves following a single drop of 0." | 1.27 | The therapy of Adie's syndrome with dilute pilocarpine hydrochloride solutions. ( Dolan, BJ; Flach, AJ, 1985) |
| "In this paper two cases of Adie's syndrome are discussed." | 1.26 | [Observations in two cases of Adie's syndrome (author's transl)]. ( Pasco, M, 1980) |
| "Most of the patients with Adie's syndrome had a moderate accomodative paresis, but there was a strong tendency for the ciliary muscle to recover with time." | 1.26 | Ciliary muscle dysfunction in Adie's syndrome. ( Bell, RA; Thompson, HS, 1978) |
| "In patients with unilateral Adie's syndrome, we compared the relative supersensitivity of the tonic pupil to methacholine hydrochloride (Mecholyl 2." | 1.26 | Cholinergic supersensitivity of the iris sphincter in Adie's tonic pupil. ( Bourgon, P; Pilley, FJ; Thompson, HS, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (69.57) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (8.70) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Batawi, H | 1 |
| Micieli, JA | 1 |
| Yoo, YJ | 1 |
| Hwang, JM | 1 |
| Yang, HK | 1 |
| Rivero Rodríguez, D | 1 |
| Scherle Matamoros, C | 1 |
| Pernas Sánchez, Y | 1 |
| Szabo, B | 1 |
| Popescu, LA | 1 |
| Rusu, A | 1 |
| Selhorst, JB | 1 |
| Flach, AJ | 2 |
| Dolan, BJ | 2 |
| Pasco, M | 1 |
| Kardon, RH | 1 |
| Corbett, JJ | 1 |
| Thompson, HS | 4 |
| Jacobson, DM | 1 |
| Vierkant, RA | 1 |
| Bell, RA | 1 |
| Bourgon, P | 1 |
| Pilley, FJ | 1 |
| Younge, BR | 1 |
| Buski, ZJ | 1 |
| Karlov, VA | 1 |
| Savitskaia, ON | 1 |
| Cohen, DN | 1 |
| Zakov, ZN | 1 |
| Drummond, PD | 1 |
| Edis, RH | 1 |
| Ramsay, DA | 1 |
| Borgmann, H | 1 |
| Thies, O | 1 |
| Brüning, E | 1 |
| Schäfer, WD | 1 |
| Richter, G | 1 |
| Szubinska-Marlicz, M | 1 |
| Markiewicz-Jablonska, E | 1 |
| Yokota, M | 1 |
| Takeda, M | 1 |
| Newsome, DA | 1 |
| Loewenfeld, IE | 1 |
| Goldsmith, MO | 1 |
1 review available for pilocarpine and Adie Syndrome
| Article | Year |
|---|---|
The pupil and its disorders.
Topics: Adie Syndrome; Autonomic Nervous System Diseases; Cranial Nerve Diseases; Horner Syndrome; Humans; I | 1983 |
22 other studies available for pilocarpine and Adie Syndrome
| Article | Year |
|---|---|
Adie's tonic pupil presenting with unilateral photophobia successfully treated with dilute pilocarpine.
Topics: Adie Syndrome; Adult; Diagnosis, Differential; Humans; Male; Photophobia; Pilocarpine; Tonic Pupil | 2020 |
Dilute pilocarpine test for diagnosis of Adie's tonic pupil.
Topics: Adie Syndrome; Adult; Aged; Case-Control Studies; Female; Humans; Male; Middle Aged; Pilocarpine; Re | 2021 |
Adie pupil. Pilocarpine test.
Topics: Adie Syndrome; Female; Humans; Miotics; Photography; Pilocarpine; Young Adult | 2018 |
[Tonic pupil, pupil Adie syndrome Adie Holmes: current reassessment of terminology -- a clinical case].
Topics: Adie Syndrome; Adult; Diagnosis, Differential; Humans; Male; Miotics; Pilocarpine; Predictive Value | 2012 |
Adie's syndrome: a medical treatment for symptomatic patients.
Topics: Accommodation, Ocular; Adie Syndrome; Adult; Eyeglasses; Female; Humans; Pilocarpine | 1984 |
[Observations in two cases of Adie's syndrome (author's transl)].
Topics: Accommodation, Ocular; Adie Syndrome; Adult; Chronic Disease; Diagnosis, Differential; Female; Human | 1980 |
Segmental denervation and reinnervation of the iris sphincter as shown by infrared videographic transillumination.
Topics: Adie Syndrome; Adult; Aged; Denervation; Humans; Infrared Rays; Iris; Light; Middle Aged; Nerve Rege | 1998 |
Comparison of cholinergic supersensitivity in third nerve palsy and Adie's syndrome.
Topics: Adie Syndrome; Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinergic Fibe | 1998 |
Ciliary muscle dysfunction in Adie's syndrome.
Topics: Accommodation, Ocular; Adie Syndrome; Adolescent; Adult; Astigmatism; Child; Ciliary Body; Female; H | 1978 |
Cholinergic supersensitivity of the iris sphincter in Adie's tonic pupil.
Topics: Adie Syndrome; Cholinergic Fibers; Drug Evaluation; Humans; Methacholine Compounds; Muscle, Smooth; | 1978 |
Tonic pupil: a simple screening test.
Topics: Adie Syndrome; Adult; False Positive Reactions; Female; Humans; Male; Pilocarpine | 1976 |
[The clinical picture and therapy of patients with Adie's syndrome].
Topics: Adie Syndrome; Adult; Female; Humans; Pilocarpine | 1975 |
The diagnosis of Adie's pupil using 0.0625% pilocarpine solution.
Topics: Adie Syndrome; Adult; Humans; Male; Ophthalmic Solutions; Pilocarpine | 1975 |
Loss of facial sweating and flushing in Holmes-Adie syndrome.
Topics: Adie Syndrome; Body Temperature Regulation; Cocaine; Female; Flushing; Humans; Middle Aged; Phenylep | 1990 |
Dilute solutions of phenylephrine and pilocarpine in the diagnosis of disordered autonomic innervation of the iris. Observations in normal subjects, and in the syndromes of Horner and Holmes-Adie.
Topics: Adie Syndrome; Adult; Autonomic Nervous System; Female; Horner Syndrome; Humans; Iris; Male; Middle | 1986 |
The therapy of Adie's syndrome with dilute pilocarpine hydrochloride solutions.
Topics: Adie Syndrome; Dose-Response Relationship, Drug; Humans; Ophthalmic Solutions; Pilocarpine; Reflex, | 1985 |
[Pharmacodynamic studies in pupillotonia].
Topics: Adie Syndrome; Carbachol; Humans; Methacholine Compounds; Pilocarpine; Pupil | 1974 |
[Importance of the mecholyl test for the diagnosis of pupillotonia].
Topics: Adie Syndrome; Cocaine; Humans; Methacholine Compounds; Pilocarpine; Syndrome | 1972 |
[Remarks on Adie's syndrome].
Topics: Adie Syndrome; Cocaine; Female; Humans; Methacholine Compounds; Pilocarpine; Pupil | 1974 |
[Case of Adie's syndrome].
Topics: Adie Syndrome; Adult; Female; Humans; Methacholine Compounds; Phenylephrine; Pilocarpine; Pupil; Tro | 1971 |
The fixed dilated pupil. Sudden iridoplegia or mydriatic drops? A simple diagnostic test.
Topics: Adie Syndrome; Adolescent; Adult; Aneurysm; Atropine; Carotid Artery Diseases; Chlorides; Diagnosis, | 1971 |
Tonic pupil following varicella.
Topics: Accommodation, Ocular; Adie Syndrome; Chickenpox; Child; Dexamethasone; Humans; Iritis; Light; Male; | 1968 |