Page last updated: 2024-11-08

pilocarpine and Ache

pilocarpine has been researched along with Ache in 23 studies

Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.

Research Excerpts

ExcerptRelevanceReference
"This study aimed to compare the safety and effect on intraocular pressure (IOP) of latanoprost given every evening versus pilocarpine/timolol maleate fixed combination (PTFC) given twice daily in patients with primary open-angle glaucoma (POAG) or ocular hypertension (OH)."9.13Efficacy and safety of latanoprost versus pilocarpine/timolol maleate fixed combination in patients with primary open-angle glaucoma or ocular hypertension. ( Czechowicz-Janicka, K; Kałuzny, BJ; Kałuzny, J; Kecik, D; Sobecki, R; Stewart, JA; Stewart, WC, 2008)
"This study aimed to compare the safety and effect on intraocular pressure (IOP) of latanoprost given every evening versus pilocarpine/timolol maleate fixed combination (PTFC) given twice daily in patients with primary open-angle glaucoma (POAG) or ocular hypertension (OH)."5.13Efficacy and safety of latanoprost versus pilocarpine/timolol maleate fixed combination in patients with primary open-angle glaucoma or ocular hypertension. ( Czechowicz-Janicka, K; Kałuzny, BJ; Kałuzny, J; Kecik, D; Sobecki, R; Stewart, JA; Stewart, WC, 2008)
" This article presents a case of painful sialoadenomegaly associated with hyperamylasemia in a bulimic patient successfully managed with pilocarpine."3.75Painful parotid hypertrophy with bulimia: a report of medical management. ( de Luzuriaga, AR; Park, KK; Tung, RC, 2009)
"The present study examines the effect of acetylcholine (ACh), muscarinic acetylcholine receptors (mAChRs) agonist pilocarpine and mAChRs antagonist atropine on the pain-evoked response of pain-excited neurons (PEN) and pain-inhibited neurons (PIN) in the hippocampal CA1 of rats."3.74Both endogenous and exogenous ACh plays antinociceptive role in the hippocampus CA1 of rats. ( Xiao, Y; Xu, MY; Yang, XF, 2008)
"To quantify the variability in thermal pain perception of rats with chemically induced brain injury following subcutaneous lithium and pilocarpine administration, 9 female Wistar rats were subjected to a nociceptive (hotplate) paradigm."3.72Elevated nociceptive thresholds in rats with multifocal brain damage induced with single subcutaneous injections of lithium and pilocarpine. ( Galic, MA, 2004)
"Intra-arterial injection of increasing doses of acetylcholine, nicotine, carbachol and pilocarpine into the pain reflex ear of the rabbit dose-dependently caused a reflex fall in mean arterial blood pressure."3.66Nicotinic nociceptors on perivascular sensory nerve endings. ( Juan, H, 1982)
"D."2.71Mutans streptococci in xerostomic cancer patients after pilocarpine therapy: a pilot study. ( Chambers, MS; Gallagher, SC; Keene, HJ; Lemon, JC; Martin, CG; Martin, JW; Toth, BB, 2005)
"Carbachol has the strongest side effects (maximal change of the anterior chamber 0."1.26Ultrasonographic study of the effect of different miotics on the eye components. ( François, J; Goes, F, 1977)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199011 (47.83)18.7374
1990's1 (4.35)18.2507
2000's8 (34.78)29.6817
2010's2 (8.70)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Coggon, D1
Ntani, G1
Walker-Bone, K1
Felli, VE1
Harari, R1
Barrero, LH1
Felknor, SA1
Rojas, M1
Cattrell, A1
Serra, C1
Bonzini, M1
Solidaki, E1
Merisalu, E1
Habib, RR1
Sadeghian, F1
Kadir, MM1
Wickremasinghe, AR1
Matsudaira, K1
Nyantumbu-Mkhize, B1
Kelsall, HL1
Harcombe, H1
Rapacz, A1
Rybka, S1
Obniska, J1
Sałat, K1
Powroźnik, B1
Pękala, E1
Filipek, B1
Kałuzny, J1
Sobecki, R1
Czechowicz-Janicka, K1
Kecik, D1
Kałuzny, BJ1
Stewart, JA1
Stewart, WC1
Jiao, R1
Yang, C1
Zhang, Y1
Xu, M1
Yang, X1
Park, KK1
Tung, RC1
de Luzuriaga, AR1
Bosdotter Enroth, S1
Rystedt, A1
Covaciu, L1
Hymnelius, K1
Rystedt, E1
Nyberg, R1
Naver, H1
Swartling, C1
Galic, MA1
Chambers, MS1
Keene, HJ1
Toth, BB1
Lemon, JC1
Gallagher, SC1
Martin, CG1
Martin, JW1
Yang, XF1
Xiao, Y1
Xu, MY1
Hitchings, RA1
Juan, H1
Womer, DE1
Shannon, HE1
Mercadante, S1
Calderone, L1
Villari, P1
Serretta, R1
Sapio, M1
Casuccio, A1
Fulfaro, F1
François, J1
Goes, F1
Meyer, HJ1
Khayutin, VM1
Baraz, LA1
Lukoshkova, EV1
Sonina, RS1
Chernilovskaya, PE1
Lubin, E1
Kest, B1
Bodnar, RJ1
Sun, DY1
Guo, Y1
Wang, WQ1
Jiang, EK1
Gao, DM1
Li, XQ1
Sjaastad, O1
Lowe, RF1
Allen, JA1
Armstrong, JE1
Roddie, IC1
Schwarz, V1
Sutcliffe, CH1
Style, PP1
Kanski, JJ1

Trials

2 trials available for pilocarpine and Ache

ArticleYear
Efficacy and safety of latanoprost versus pilocarpine/timolol maleate fixed combination in patients with primary open-angle glaucoma or ocular hypertension.
    Acta ophthalmologica, 2008, Volume: 86, Issue:8

    Topics: Aged; Drug Administration Schedule; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; In

2008
Mutans streptococci in xerostomic cancer patients after pilocarpine therapy: a pilot study.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2005, Volume: 99, Issue:2

    Topics: Analgesics, Opioid; Colony Count, Microbial; Female; Follow-Up Studies; Humans; Longitudinal Studies

2005

Other Studies

21 other studies available for pilocarpine and Ache

ArticleYear
Associations of sickness absence for pain in the low back, neck and shoulders with wider propensity to pain.
    Occupational and environmental medicine, 2020, Volume: 77, Issue:5

    Topics: Absenteeism; Adult; Female; Global Health; Humans; Logistic Models; Low Back Pain; Male; Middle Aged

2020
Evaluation of anticonvulsant and antinociceptive properties of new N-Mannich bases derived from pyrrolidine-2,5-dione and 3-methylpyrrolidine-2,5-dione.
    Naunyn-Schmiedeberg's archives of pharmacology, 2016, Volume: 389, Issue:3

    Topics: Analgesics; Animals; Anticonvulsants; Calcium Channels, L-Type; Formaldehyde; Hot Temperature; Male;

2016
Cholinergic mechanism involved in the nociceptive modulation of dentate gyrus.
    Biochemical and biophysical research communications, 2009, Feb-20, Volume: 379, Issue:4

    Topics: Acetylcholine; Animals; Atropine; Cells, Cultured; Dentate Gyrus; Muscarinic Antagonists; Nociceptor

2009
Painful parotid hypertrophy with bulimia: a report of medical management.
    Journal of drugs in dermatology : JDD, 2009, Volume: 8, Issue:6

    Topics: Adult; Bulimia; Female; Humans; Hyperamylasemia; Hypertrophy; Pain; Parotid Gland; Pilocarpine; Subl

2009
Bilateral forearm intravenous regional anesthesia with prilocaine for botulinum toxin treatment of palmar hyperhidrosis.
    Journal of the American Academy of Dermatology, 2010, Volume: 63, Issue:3

    Topics: Adolescent; Adult; Anesthesia, Conduction; Anesthesia, Intravenous; Botulinum Toxins; Cohort Studies

2010
Elevated nociceptive thresholds in rats with multifocal brain damage induced with single subcutaneous injections of lithium and pilocarpine.
    Perceptual and motor skills, 2004, Volume: 98, Issue:3 Pt 1

    Topics: Acepromazine; Animals; Antipsychotic Agents; Brain Injuries; Epilepsy, Temporal Lobe; Female; Inject

2004
Both endogenous and exogenous ACh plays antinociceptive role in the hippocampus CA1 of rats.
    Journal of neural transmission (Vienna, Austria : 1996), 2008, Volume: 115, Issue:1

    Topics: Acetylcholine; Animals; Atropine; Electric Stimulation; Evoked Potentials; Female; Hippocampus; Inje

2008
The symptom of ocular pain.
    Transactions of the ophthalmological societies of the United Kingdom, 1980, Volume: 100, Issue:Pt 2

    Topics: Eye; Eye Diseases; Glaucoma; Humans; Iritis; Light; Light Coagulation; Pain; Pain, Postoperative; Pi

1980
Nicotinic nociceptors on perivascular sensory nerve endings.
    Pain, 1982, Volume: 12, Issue:3

    Topics: Acetylcholine; Analgesics; Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Morphine;

1982
Reversal of pertussis toxin-induced thermal allodynia by muscarinic cholinergic agonists in mice.
    Neuropharmacology, 2000, Volume: 39, Issue:12

    Topics: Animals; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Hot Temperature; Injections, S

2000
The use of pilocarpine in opioid-induced xerostomia.
    Palliative medicine, 2000, Volume: 14, Issue:6

    Topics: Administration, Oral; Aged; Female; Humans; Male; Middle Aged; Muscarinic Agonists; Narcotics; Neopl

2000
Ultrasonographic study of the effect of different miotics on the eye components.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1977, Volume: 175, Issue:6

    Topics: Administration, Topical; Adult; Anterior Chamber; Carbachol; Epinephrine; Eye; Humans; Lens, Crystal

1977
[Dangers of ocusert therapy (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1977, Volume: 171, Issue:4

    Topics: Aged; Delayed-Action Preparations; Ethylenes; Glaucoma; Humans; Male; Pain; Pharmaceutical Vehicles;

1977
Chemosensitive spinal afferents: thresholds of specific and nociceptive reflexes as compared with thresholds of excitation for receptors and axons.
    Progress in brain research, 1976, Volume: 43

    Topics: Acetylcholine; Animals; Blood Pressure; Bradykinin; Carbachol; Cats; Chemoreceptor Cells; Histamine;

1976
Differential actions of central alloxan upon opioid and nonopioid antinociception in rats: a further examination.
    Brain research bulletin, 1991, Volume: 27, Issue:1

    Topics: Alloxan; Animals; Deoxyglucose; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Pain; Pi

1991
[The reverse effect of intracaudate injection of pilocarpine on antielectroacupuncture analgesia induced by the intracaudate injection of dopamine].
    Zhen ci yan jiu = Acupuncture research, 1987, Volume: 12, Issue:2

    Topics: Acupuncture Therapy; Animals; Caudate Nucleus; Dopamine Antagonists; Electric Stimulation; Female; M

1987
Cluster headache and its variants.
    Headache, 1988, Volume: 28, Issue:10

    Topics: Age Factors; Chronic Disease; Cluster Headache; Diagnosis, Differential; Female; Humans; Middle Aged

1988
Persistent symptoms after peripheral iridectomy for angle-closure glaucoma.
    Australian and New Zealand journal of ophthalmology, 1987, Volume: 15, Issue:1

    Topics: Acute Disease; Adult; Aged; Female; Glaucoma; Humans; Intraocular Pressure; Iris; Middle Aged; Pain;

1987
Sweat responses of a hyperhidrotic subject.
    The British journal of dermatology, 1974, Volume: 90, Issue:3

    Topics: Adult; Blood Flow Velocity; Body Weight; Epinephrine; Hand; Humans; Male; Mathematics; Pain; Physica

1974
Some hazards of the sweat test.
    Archives of disease in childhood, 1968, Volume: 43, Issue:232

    Topics: Blister; Burns, Chemical; Burns, Electric; Child; Cystic Fibrosis; Electrodiagnosis; Humans; Hydroch

1968
Miotics.
    The British journal of ophthalmology, 1968, Volume: 52, Issue:12

    Topics: Acetylcholine; Anterior Chamber; Carbachol; Cataract; Cholinesterase Inhibitors; Cysts; Echothiophat

1968