pilocarpine has been researched along with Abdominal Epilepsy in 14 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Excerpt | Relevance | Reference |
---|---|---|
"Limbic seizures were evoked in freely moving rats by intrahippocampal administration of pilocarpine via a microdialysis probe." | 7.73 | Substantia nigra is an anticonvulsant site of action of topiramate in the focal pilocarpine model of limbic seizures. ( Clinckers, R; Ebinger, G; Meurs, A; Michotte, Y; Smolders, I, 2006) |
"Pilocarpine-treated animals, which did not develop status epilepticus, showed no change in growth-associated phosphoprotein levels, indicating that status epilepticus is important to induce growth-associated phosphoprotein overexpression." | 5.30 | Growth-associated phosphoprotein expression is increased in the supragranular regions of the dentate gyrus following pilocarpine-induced seizures in rats. ( Cavalheiro, EA; Funke, MG; Naffah-Mazzacoratti, MG; Sanabria, ER, 1999) |
"Limbic seizures were evoked in freely moving rats by intrahippocampal administration of pilocarpine via a microdialysis probe." | 3.73 | Substantia nigra is an anticonvulsant site of action of topiramate in the focal pilocarpine model of limbic seizures. ( Clinckers, R; Ebinger, G; Meurs, A; Michotte, Y; Smolders, I, 2006) |
"In the present study glutamate decarboxylase immunoreactivity (GAD-IR) was used to quantify GABAergic neurons in the hippocampus of rats exhibiting spontaneous recurrent seizures following pilocarpine-induced status epilepticus." | 3.68 | GAD-immunoreactive neurons are preserved in the hippocampus of rats with spontaneous recurrent seizures. ( Cavalheiro, EA, 1990) |
"Interictal activity and seizures are the hallmarks of focal epileptic disorders (which include mesial temporal lobe epilepsy, MTLE) in humans and in animal models." | 3.01 | Evolution of interictal activity in models of mesial temporal lobe epilepsy. ( Avoli, M; Lévesque, M; Macey-Dare, ADB; Salami, P; Wang, S, 2023) |
" hM4Di has no effect in the absence of its selective, normally inactive and orally bioavailable agonist clozapine-N-oxide (CNO)." | 1.40 | Chemical-genetic attenuation of focal neocortical seizures. ( Kätzel, D; Kullmann, DM; Nicholson, E; Schorge, S; Walker, MC, 2014) |
"Pilocarpine-treated animals, which did not develop status epilepticus, showed no change in growth-associated phosphoprotein levels, indicating that status epilepticus is important to induce growth-associated phosphoprotein overexpression." | 1.30 | Growth-associated phosphoprotein expression is increased in the supragranular regions of the dentate gyrus following pilocarpine-induced seizures in rats. ( Cavalheiro, EA; Funke, MG; Naffah-Mazzacoratti, MG; Sanabria, ER, 1999) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (28.57) | 18.2507 |
2000's | 6 (42.86) | 29.6817 |
2010's | 3 (21.43) | 24.3611 |
2020's | 1 (7.14) | 2.80 |
Authors | Studies |
---|---|
Lévesque, M | 1 |
Wang, S | 1 |
Macey-Dare, ADB | 1 |
Salami, P | 1 |
Avoli, M | 1 |
Yi, PL | 2 |
Lu, CY | 2 |
Cheng, CH | 1 |
Tsai, YF | 1 |
Lin, CT | 1 |
Chang, FC | 2 |
Kätzel, D | 1 |
Nicholson, E | 1 |
Schorge, S | 1 |
Walker, MC | 1 |
Kullmann, DM | 1 |
Jou, SB | 1 |
Trindade-Filho, EM | 1 |
de Castro-Neto, EF | 1 |
de A Carvalho, R | 1 |
Lima, E | 1 |
Scorza, FA | 1 |
Amado, D | 1 |
Naffah-Mazzacoratti, Mda G | 1 |
Cavalheiro, EA | 4 |
Xia, Y | 1 |
Lai, Y | 1 |
Lei, L | 1 |
Liu, Y | 1 |
Yao, D | 1 |
Kohane, DS | 1 |
Holmes, GL | 1 |
Chau, Y | 1 |
Zurakowski, D | 1 |
Langer, R | 1 |
Cha, BH | 1 |
Meurs, A | 1 |
Clinckers, R | 1 |
Ebinger, G | 2 |
Michotte, Y | 2 |
Smolders, I | 2 |
Milh, M | 1 |
Becq, H | 1 |
Villeneuve, N | 1 |
Ben-Ari, Y | 1 |
Aniksztejn, L | 1 |
Naffah-Mazzacoratti, MG | 1 |
Funke, MG | 1 |
Sanabria, ER | 1 |
Lindekens, H | 1 |
Khan, GM | 1 |
Bialer, M | 1 |
Fernandes, MJ | 1 |
Turski, L | 1 |
Mazzacoratti, MG | 1 |
Fine, A | 1 |
Meldrum, BS | 1 |
Patel, S | 1 |
1 review available for pilocarpine and Abdominal Epilepsy
Article | Year |
---|---|
Evolution of interictal activity in models of mesial temporal lobe epilepsy.
Topics: Animals; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Humans; Pil | 2023 |
13 other studies available for pilocarpine and Abdominal Epilepsy
Article | Year |
---|---|
Amygdala opioid receptors mediate the electroacupuncture-induced deterioration of sleep disruptions in epilepsy rats.
Topics: Amygdala; Animals; Electroacupuncture; Epilepsies, Partial; Male; Naloxone; Narcotic Antagonists; Pi | 2013 |
Chemical-genetic attenuation of focal neocortical seizures.
Topics: Acute Disease; Animals; Clozapine; Epilepsies, Partial; Gene Silencing; Genetic Therapy; Humans; Mal | 2014 |
Low-frequency electroacupuncture suppresses focal epilepsy and improves epilepsy-induced sleep disruptions.
Topics: Animals; Electroacupuncture; Electroencephalography; Epilepsies, Partial; Humans; Naloxone; Pilocarp | 2015 |
Serotonin depletion effects on the pilocarpine model of epilepsy.
Topics: 5,7-Dihydroxytryptamine; Acute Disease; Animals; Behavior, Animal; Chronic Disease; Disease Models, | 2008 |
Left hemisphere predominance of pilocarpine-induced rat epileptiform discharges.
Topics: Animals; Azides; Cerebral Cortex; Disease Models, Animal; Epilepsies, Partial; Functional Laterality | 2009 |
Effectiveness of muscimol-containing microparticles against pilocarpine-induced focal seizures.
Topics: Animals; Anticonvulsants; Drug Carriers; Drug Implants; Epilepsies, Partial; GABA-A Receptor Agonist | 2002 |
Substantia nigra is an anticonvulsant site of action of topiramate in the focal pilocarpine model of limbic seizures.
Topics: Animals; Anticonvulsants; Area Under Curve; Behavior, Animal; Disease Models, Animal; Dose-Response | 2006 |
Inhibition of glutamate transporters results in a "suppression-burst" pattern and partial seizures in the newborn rat.
Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Cerebral Cortex; Disease | 2007 |
Growth-associated phosphoprotein expression is increased in the supragranular regions of the dentate gyrus following pilocarpine-induced seizures in rats.
Topics: Animals; Dentate Gyrus; Epilepsies, Partial; GAP-43 Protein; Immunohistochemistry; Male; Phosphoprot | 1999 |
In vivo study of the effect of valpromide and valnoctamide in the pilocarpine rat model of focal epilepsy.
Topics: Amides; Animals; Anti-Anxiety Agents; Anticonvulsants; Epilepsies, Partial; gamma-Aminobutyric Acid; | 2000 |
Neurochemical changes in the hippocampus of rats with spontaneous recurrent seizures.
Topics: Amino Acids; Animals; Dopamine; Electroencephalography; Epilepsies, Partial; Hippocampus; Male; Moto | 1992 |
GAD-immunoreactive neurons are preserved in the hippocampus of rats with spontaneous recurrent seizures.
Topics: Animals; Epilepsies, Partial; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Male; N | 1990 |
Modulation of experimentally induced epilepsy by intracerebral grafts of fetal GABAergic neurons.
Topics: Animals; Brain Mapping; Caudate Nucleus; Epilepsies, Partial; Fetus; Kindling, Neurologic; Male; Ner | 1990 |