pifithrin has been researched along with Status Epilepticus in 1 studies
pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source
Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Engel, T | 1 |
| Murphy, BM | 1 |
| Hatazaki, S | 1 |
| Jimenez-Mateos, EM | 1 |
| Concannon, CG | 1 |
| Woods, I | 1 |
| Prehn, JH | 1 |
| Henshall, DC | 1 |
1 other study available for pifithrin and Status Epilepticus
| Article | Year |
|---|---|
Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma.
Topics: Animals; Apoptosis Regulatory Proteins; Benzothiazoles; Blotting, Western; Epilepsy; Genotype; Hippo | 2010 |