pifithrin has been researched along with Rett Syndrome in 1 studies
pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source
Rett Syndrome: An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Samarasinghe, RA | 1 |
| Miranda, OA | 1 |
| Buth, JE | 1 |
| Mitchell, S | 1 |
| Ferando, I | 1 |
| Watanabe, M | 1 |
| Allison, TF | 1 |
| Kurdian, A | 1 |
| Fotion, NN | 1 |
| Gandal, MJ | 1 |
| Golshani, P | 1 |
| Plath, K | 1 |
| Lowry, WE | 1 |
| Parent, JM | 1 |
| Mody, I | 1 |
| Novitch, BG | 1 |
1 other study available for pifithrin and Rett Syndrome
| Article | Year |
|---|---|
Identification of neural oscillations and epileptiform changes in human brain organoids.
Topics: Adult; Benzothiazoles; Brain; Calcium Signaling; Child, Preschool; Epilepsy; Female; Humans; Induced | 2021 |