pifithrin has been researched along with Pulmonary Hypertension in 1 studies
pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| " We therefore explored the involvement of p53 in the monocrotaline (MCT) rat model of pulmonary hypertension (PH) and the pathophysiological consequences of p53 inactivation in response to animal treatment with pifithrin-α (PFT, an inhibitor of p53 activity)." | 3.81 | Inactivation of p53 Is Sufficient to Induce Development of Pulmonary Hypertension in Rats. ( Eddahibi, S; Fadel, E; Humbert, M; Jacquin, S; Londoño-Vallejo, A; Mercier, O; Mignotte, B; Richard, S; Rincheval, V, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacquin, S | 1 |
| Rincheval, V | 1 |
| Mignotte, B | 1 |
| Richard, S | 1 |
| Humbert, M | 1 |
| Mercier, O | 1 |
| Londoño-Vallejo, A | 1 |
| Fadel, E | 1 |
| Eddahibi, S | 1 |
1 other study available for pifithrin and Pulmonary Hypertension
| Article | Year |
|---|---|
Inactivation of p53 Is Sufficient to Induce Development of Pulmonary Hypertension in Rats.
Topics: Animals; Apoptosis; Benzothiazoles; Cell Proliferation; Humans; Hypertension, Pulmonary; Hypertrophy | 2015 |