pifithrin has been researched along with Pregnancy in 8 studies
pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Ueharu, H | 1 |
| Pan, H | 1 |
| Hayano, S | 1 |
| Zapien-Guerra, K | 1 |
| Yang, J | 1 |
| Mishina, Y | 2 |
| Chen, YH | 1 |
| Bae, E | 1 |
| Chen, H | 1 |
| Yu, SJ | 1 |
| Harvey, BK | 1 |
| Greig, NH | 1 |
| Wang, Y | 1 |
| Dong, Y | 1 |
| Ito, T | 1 |
| Velayo, C | 1 |
| Sato, T | 1 |
| Iida, K | 1 |
| Endo, M | 1 |
| Funamoto, K | 1 |
| Sato, N | 1 |
| Yaegashi, N | 1 |
| Kimura, Y | 1 |
| Li, X | 1 |
| Gu, S | 1 |
| Ling, Y | 1 |
| Shen, C | 1 |
| Cao, X | 1 |
| Xie, R | 1 |
| Cohen, M | 1 |
| Wuillemin, C | 1 |
| Irion, O | 1 |
| Bischof, P | 1 |
| Castranio, T | 1 |
| Chen, B | 1 |
| Longtine, MS | 1 |
| Sadovsky, Y | 1 |
| Nelson, DM | 1 |
| Plesnila, N | 1 |
| von Baumgarten, L | 1 |
| Retiounskaia, M | 1 |
| Engel, D | 1 |
| Ardeshiri, A | 1 |
| Zimmermann, R | 1 |
| Hoffmann, F | 1 |
| Landshamer, S | 1 |
| Wagner, E | 1 |
| Culmsee, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Fish Oil or Probiotic Intake on Maternal Obesity and Molecular Biomarkers in the Placenta[NCT03215784] | 80 participants (Anticipated) | Interventional | 2015-03-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 other studies available for pifithrin and Pregnancy
| Article | Year |
|---|---|
Augmentation of bone morphogenetic protein signaling in cranial neural crest cells in mice deforms skull base due to premature fusion of intersphenoidal synchondrosis.
Topics: Animals; Animals, Newborn; Apoptosis; Bone Morphogenetic Proteins; Cell Proliferation; Chondrocytes; | 2023 |
Pifithrin-Alpha Reduces Methamphetamine Neurotoxicity in Cultured Dopaminergic Neurons.
Topics: Animals; Benzothiazoles; Cell Line, Tumor; Cells, Cultured; Central Nervous System Stimulants; Dopam | 2019 |
Intrauterine ischemic reperfusion switches the fetal transcriptional pattern from HIF-1α- to P53-dependent regulation in the murine brain.
Topics: Animals; Benzothiazoles; Brain Injuries; Female; Fetus; Gene Expression Regulation; Hypoxia-Inducibl | 2014 |
p53 inhibition provides a pivotal protective effect against ischemia-reperfusion injury in vitro via mTOR signaling.
Topics: Animals; Benzothiazoles; Cells, Cultured; Female; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective | 2015 |
Regulation of MMP-9 by p53 in first trimester cytotrophoblastic cells.
Topics: Benzothiazoles; Blotting, Western; Etoposide; Female; Gene Expression Regulation, Developmental; Hum | 2008 |
Bmp2 is required for cephalic neural tube closure in the mouse.
Topics: Animals; Apoptosis; Benzothiazoles; Body Patterning; Bone Morphogenetic Protein 2; Chimera; Female; | 2009 |
Hypoxia downregulates p53 but induces apoptosis and enhances expression of BAD in cultures of human syncytiotrophoblasts.
Topics: Animals; Apoptosis; bcl-Associated Death Protein; Benzothiazoles; Cells, Cultured; Down-Regulation; | 2010 |
Delayed neuronal death after brain trauma involves p53-dependent inhibition of NF-kappaB transcriptional activity.
Topics: Animals; Apoptosis; Benzothiazoles; Brain Injuries; Disease Models, Animal; Female; Humans; Male; Mi | 2007 |