pifithrin has been researched along with Pancreatic Neoplasms in 2 studies
pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pancreatic cancer is an exceedingly lethal disease with a five-year survival that ranks among the lowest of gastrointestinal malignancies." | 1.38 | Evidence for activation of mutated p53 by apigenin in human pancreatic cancer. ( Chen, M; Eibl, G; Go, VL; Hines, OJ; King, JC; Li, G; Lu, QY; Moro, A; Reber, HA; Takahashi, H, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bu, HQ | 1 |
| Liu, DL | 1 |
| Wei, WT | 1 |
| Chen, L | 1 |
| Huang, H | 1 |
| Li, Y | 1 |
| Cui, JH | 1 |
| King, JC | 1 |
| Lu, QY | 1 |
| Li, G | 1 |
| Moro, A | 1 |
| Takahashi, H | 1 |
| Chen, M | 1 |
| Go, VL | 1 |
| Reber, HA | 1 |
| Eibl, G | 1 |
| Hines, OJ | 1 |
2 other studies available for pifithrin and Pancreatic Neoplasms
| Article | Year |
|---|---|
Oridonin induces apoptosis in SW1990 pancreatic cancer cells via p53- and caspase-dependent induction of p38 MAPK.
Topics: Anthracenes; Apoptosis; Benzothiazoles; Caspase 3; Caspase 9; Cell Line, Tumor; Cyclin-Dependent Kin | 2014 |
Evidence for activation of mutated p53 by apigenin in human pancreatic cancer.
Topics: Animals; Apigenin; Apoptosis; Apoptosis Regulatory Proteins; bcl-X Protein; Benzothiazoles; Cell Lin | 2012 |